| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 930,100 | 1,325,700 | +395,600 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 60,166 | 253,283 | +193,117 | 0.00 | 0.00 | +0.00 | buy |
| Congress Park Capital LLC | 112,450 | 239,300 | +126,850 | 0.08 | 0.18 | +0.10 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 104,162 | +104,162 | 0.00 | 0.01 | +0.01 | buy |
| TANG CAPITAL MANAGEMENT LLC | 6,450,000 | 6,550,000 | +100,000 | 1.17 | 0.94 | -0.24 | buy |
| MILLENNIUM MANAGEMENT LLC | 698,906 | 794,047 | +95,141 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 71,300 | +71,300 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 372,124 | 434,524 | +62,400 | 0.01 | 0.01 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 145,934 | 196,520 | +50,586 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 676,343 | 702,654 | +26,311 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 20,273 | +20,273 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 119,919 | 135,302 | +15,383 | 0.00 | 0.00 | +0.00 | buy |
| IPG Investment Advisors LLC | 0 | 12,500 | +12,500 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 105,392 | 110,265 | +4,873 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 15,637 | 19,679 | +4,042 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 1,415 | 3,485 | +2,070 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 1,251 | +1,251 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 274 | +274 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 4,902,943 | 4,902,943 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BVF INC/IL | 6,595,801 | 6,595,801 | 0 | 0.23 | 0.26 | +0.03 | hold |
| CORNERCAP INVESTMENT COUNSEL INC | 81,352 | 81,352 | 0 | 0.02 | 0.02 | +0.00 | hold |
| RHUMBLINE ADVISERS | 1,291 | 1,291 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRUDENTIAL FINANCIAL INC | 16,300 | 16,300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| WHITTIER TRUST CO | 6,604 | 6,604 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bank of New York Mellon Corp | 266,836 | 266,836 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Private Advisor Group, LLC | 73,179 | 73,179 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Vontobel Holding Ltd. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Clearline Capital LP | 196,583 | 196,583 | 0 | 0.03 | 0.03 | +0.01 | hold |
| Qube Research & Technologies Ltd | 259 | 259 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WestHill Financial Advisors, Inc. | 17,082 | 17,082 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Byrne Asset Management LLC | 8,000 | 8,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Raleigh Capital Management Inc. | 250 | 250 | 0 | 0.00 | 0.00 | +0.00 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 53,243 | 53,243 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FRANKLIN RESOURCES INC | 26,838 | 26,838 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 24,817 | 24,817 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 2,646,190 | 2,646,190 | 0 | 0.01 | 0.02 | +0.00 | hold |
| TUDOR INVESTMENT CORP ET AL | 44,730 | 44,730 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GROUP ONE TRADING LLC | 637 | 637 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 267,476 | 267,476 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 236 | 78 | -158 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 8,231 | 7,184 | -1,047 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 45,626 | 41,725 | -3,901 | 0.00 | 0.00 | -0.00 | sell |
| Bronte Capital Management Pty Ltd. | 925,245 | 919,911 | -5,334 | 0.12 | 0.13 | +0.01 | sell |
| Ground Swell Capital, LLC | 10,966 | 0 | -10,966 | 0.02 | 0.00 | -0.02 | sell |
| Formidable Asset Management, LLC | 318,111 | 306,107 | -12,004 | 0.09 | 0.10 | +0.01 | sell |
| Tidal Investments LLC | 318,111 | 306,107 | -12,004 | 0.01 | 0.01 | -0.00 | sell |
| MARSHALL WACE, LLP | 377,593 | 363,276 | -14,317 | 0.00 | 0.00 | +0.00 | sell |
| Forefront Analytics, LLC | 49,421 | 30,846 | -18,575 | 0.04 | 0.02 | -0.01 | sell |
| Assenagon Asset Management S.A. | 425,921 | 404,674 | -21,247 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 22,071 | 0 | -22,071 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 173,625 | 150,533 | -23,092 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 50,092 | 14,141 | -35,951 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 73,494 | 11,577 | -61,917 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 107,900 | 41,200 | -66,700 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 88,570 | 0 | -88,570 | 0.00 | 0.00 | -0.00 | sell |
| Laurion Capital Management LP | 1,188,225 | 1,093,921 | -94,304 | 0.04 | 0.06 | +0.02 | sell |
| FMR LLC | 707,968 | 565,324 | -142,644 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 259,965 | 0 | -259,965 | 0.01 | 0.00 | -0.01 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,052,105 | 791,421 | -260,684 | 0.01 | 0.01 | -0.00 | sell |