| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ALLIANCEBERNSTEIN L.P. | 560,325 | 2,531,528 | +1,971,203 | 0.01 | 0.02 | +0.02 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,209,566 | 2,265,195 | +55,629 | 0.06 | 0.05 | -0.01 | buy |
| VANGUARD GROUP INC | 2,055,033 | 2,069,423 | +14,390 | 0.00 | 0.00 | -0.00 | buy |
| LORD, ABBETT & CO. LLC | 1,430,277 | 1,757,153 | +326,876 | 0.14 | 0.13 | -0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 1,202,408 | 1,173,918 | -28,490 | 0.45 | 0.35 | -0.11 | sell |
| Portolan Capital Management, LLC | 1,297,090 | 1,162,829 | -134,261 | 3.10 | 2.09 | -1.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 974,111 | 996,636 | +22,525 | 0.01 | 0.01 | -0.00 | buy |
| ASHFORD CAPITAL MANAGEMENT INC | 831,885 | 831,535 | -350 | 3.05 | 2.65 | -0.40 | sell |
| AMERIPRISE FINANCIAL INC | 670,710 | 824,712 | +154,002 | 0.01 | 0.01 | -0.00 | buy |
| STATE STREET CORP | 809,046 | 815,487 | +6,441 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 870,026 | 810,532 | -59,494 | 0.01 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 763,846 | 798,968 | +35,122 | 0.00 | 0.00 | -0.00 | buy |
| EMERALD ADVISERS, LLC | 574,454 | 705,447 | +130,993 | 0.67 | 0.67 | -0.00 | buy |
| Granahan Investment Management, LLC | 666,859 | 671,779 | +4,920 | 0.60 | 0.56 | -0.05 | buy |
| BAILLIE GIFFORD & CO | 631,573 | 623,355 | -8,218 | 0.01 | 0.01 | -0.00 | sell |
| Tikvah Management LLC | 571,619 | 571,619 | 0 | 5.36 | 4.22 | -1.14 | hold |
| EMERALD MUTUAL FUND ADVISERS TRUST | 473,753 | 558,841 | +85,088 | 0.69 | 0.69 | -0.00 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 184,000 | 471,000 | +287,000 | 0.03 | 0.07 | +0.03 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 474,700 | 425,386 | -49,314 | 0.02 | 0.02 | -0.00 | sell |
| PURA VIDA INVESTMENTS, LLC | 651,332 | 375,985 | -275,347 | 4.25 | 6.03 | +1.78 | sell |
| NORTHERN TRUST CORP | 366,073 | 358,405 | -7,668 | 0.00 | 0.00 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 255,139 | 340,726 | +85,587 | 0.00 | 0.00 | +0.00 | buy |
| BOONE CAPITAL MANAGEMENT LLC | 568,544 | 330,151 | -238,393 | 3.63 | 1.57 | -2.05 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 295,811 | 315,383 | +19,572 | 0.00 | 0.00 | -0.00 | buy |
| Blue Water Life Science Advisors, LP | 288,196 | 309,093 | +20,897 | 6.90 | 6.85 | -0.05 | buy |
| D. E. Shaw & Co., Inc. | 619,173 | 299,746 | -319,427 | 0.02 | 0.01 | -0.02 | sell |
| RWA WEALTH PARTNERS, LLC | 193,203 | 293,203 | +100,000 | 0.08 | 0.09 | +0.02 | buy |
| PRUDENTIAL FINANCIAL INC | 390,193 | 286,513 | -103,680 | 0.02 | 0.01 | -0.01 | sell |
| Pier Capital, LLC | 210,636 | 278,491 | +67,855 | 0.82 | 0.90 | +0.08 | buy |
| GOLDMAN SACHS GROUP INC | 291,090 | 236,731 | -54,359 | 0.00 | 0.00 | -0.00 | sell |
| PLATINUM INVESTMENT MANAGEMENT LTD | 510,753 | 217,442 | -293,311 | 0.57 | 0.21 | -0.36 | sell |
| ROYCE & ASSOCIATES LP | 215,948 | 215,948 | 0 | 0.05 | 0.05 | -0.01 | hold |
| MORGAN STANLEY | 349,883 | 215,832 | -134,051 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 225,000 | 181,651 | -43,349 | 0.21 | 0.12 | -0.09 | sell |
| Parkman Healthcare Partners LLC | 146,366 | 176,112 | +29,746 | 0.57 | 0.51 | -0.06 | buy |
| TWO SIGMA ADVISERS, LP | 236,248 | 172,548 | -63,700 | 0.02 | 0.01 | -0.01 | sell |
| FULLER & THALER ASSET MANAGEMENT, INC. | 163,230 | 158,305 | -4,925 | 0.02 | 0.02 | -0.01 | sell |
| BRIDGER MANAGEMENT, LLC | 154,900 | 154,900 | 0 | 1.62 | 1.65 | +0.02 | hold |
| AQR CAPITAL MANAGEMENT LLC | 140,607 | 147,501 | +6,894 | 0.01 | 0.01 | -0.00 | buy |
| CWM, LLC | 175,826 | 135,789 | -40,037 | 0.03 | 0.02 | -0.01 | sell |
| MARATHON CAPITAL MANAGEMENT | 105,745 | 119,135 | +13,390 | 0.73 | 0.67 | -0.06 | buy |
| Bank of New York Mellon Corp | 125,353 | 115,705 | -9,648 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 54,832 | 105,793 | +50,961 | 0.00 | 0.00 | +0.00 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 87,800 | 99,700 | +11,900 | 0.22 | 0.17 | -0.05 | buy |
| JPMORGAN CHASE & CO | 90,073 | 93,263 | +3,190 | 0.00 | 0.00 | -0.00 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 176,969 | 93,211 | -83,758 | 0.05 | 0.02 | -0.03 | sell |
| PICTON MAHONEY ASSET MANAGEMENT | 5,070 | 86,092 | +81,022 | 0.01 | 0.09 | +0.08 | buy |
| China Universal Asset Management Co., Ltd. | 85,019 | 85,019 | 0 | 0.45 | 0.25 | -0.20 | hold |
| Valmark Advisers, Inc. | 69,736 | 82,913 | +13,177 | 0.04 | 0.03 | -0.00 | buy |
| EASTERLY INVESTMENT PARTNERS LLC | 12,092 | 78,734 | +66,642 | 0.04 | 0.14 | +0.11 | buy |
| Schonfeld Strategic Advisors LLC | 49,700 | 78,200 | +28,500 | 0.01 | 0.01 | +0.00 | buy |
| Swiss National Bank | 70,300 | 70,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Squarepoint Ops LLC | 73,782 | 68,281 | -5,501 | 0.01 | 0.01 | -0.00 | sell |
| RHUMBLINE ADVISERS | 68,598 | 67,556 | -1,042 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 73,896 | 62,472 | -11,424 | 0.02 | 0.02 | -0.01 | sell |
| Clarius Group, LLC | 62,060 | 62,060 | 0 | 0.14 | 0.10 | -0.04 | hold |
| CITADEL ADVISORS LLC | 29,644 | 61,789 | +32,145 | 0.00 | 0.00 | +0.00 | buy |
| Exome Asset Management LLC | 0 | 59,650 | +59,650 | 0.00 | 1.20 | +1.20 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 50,003 | 56,633 | +6,630 | 0.00 | 0.00 | -0.00 | buy |
| Williams Jones Wealth Management, LLC. | 0 | 56,337 | +56,337 | 0.00 | 0.02 | +0.02 | buy |
| FRANKLIN RESOURCES INC | 24,273 | 54,351 | +30,078 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 33,483 | 51,736 | +18,253 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 38,753 | 49,027 | +10,274 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 61,184 | 48,541 | -12,643 | 0.00 | 0.00 | -0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 49,745 | 48,155 | -1,590 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 49,533 | 47,394 | -2,139 | 0.00 | 0.00 | -0.00 | sell |
| JUPITER ASSET MANAGEMENT LTD | 46,889 | 46,889 | 0 | 0.01 | 0.01 | -0.00 | hold |
| JANE STREET GROUP, LLC | 29,071 | 44,096 | +15,025 | 0.00 | 0.00 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 42,006 | 41,098 | -908 | 0.01 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 38,730 | 39,916 | +1,186 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 40,073 | 39,148 | -925 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 38,901 | 38,359 | -542 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 51,838 | 37,713 | -14,125 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 37,417 | 37,406 | -11 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37,576 | 35,906 | -1,670 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 35,132 | 33,491 | -1,641 | 0.01 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 69,809 | 31,931 | -37,878 | 0.00 | 0.00 | -0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 10,915 | 26,824 | +15,909 | 0.00 | 0.00 | +0.00 | buy |
| Alpha DNA Investment Management LLC | 0 | 22,193 | +22,193 | 0.00 | 0.29 | +0.29 | buy |
| Point72 Asset Management, L.P. | 276,923 | 20,321 | -256,602 | 0.02 | 0.00 | -0.02 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 10,427 | 20,191 | +9,764 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 24,830 | 20,189 | -4,641 | 0.00 | 0.00 | -0.00 | sell |
| Ashton Thomas Private Wealth, LLC | 0 | 20,100 | +20,100 | 0.00 | 0.03 | +0.03 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 18,521 | 19,497 | +976 | 0.04 | 0.03 | -0.01 | buy |
| Aberdeen Group plc | 0 | 18,837 | +18,837 | 0.00 | 0.00 | +0.00 | buy |
| Empire Financial Management Company, LLC | 18,000 | 18,750 | +750 | 0.19 | 0.15 | -0.05 | buy |
| STRS OHIO | 18,400 | 18,700 | +300 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 20,046 | 18,569 | -1,477 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 17,799 | 17,799 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMERICAN INTERNATIONAL GROUP, INC. | 17,513 | 17,572 | +59 | 0.00 | 0.00 | -0.00 | buy |
| Graham Capital Management, L.P. | 15,006 | 17,179 | +2,173 | 0.01 | 0.01 | -0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 16,794 | 16,794 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Mirae Asset Global Investments Co., Ltd. | 16,471 | 16,471 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CANADA LIFE ASSURANCE Co | 23,463 | 15,501 | -7,962 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 2,841 | 15,196 | +12,355 | 0.00 | 0.00 | +0.00 | buy |
| TRUIST FINANCIAL CORP | 15,316 | 15,157 | -159 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 0 | 14,483 | +14,483 | 0.00 | 0.03 | +0.03 | buy |
| Nebula Research & Development LLC | 8,342 | 14,421 | +6,079 | 0.07 | 0.07 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 14,410 | 14,411 | +1 | 0.00 | 0.00 | -0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 10,091 | 14,341 | +4,250 | 0.00 | 0.00 | -0.00 | buy |