| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ALLIANCEBERNSTEIN L.P. | 2,531,528 | 3,414,794 | +883,266 | 0.02 | 0.02 | -0.01 | buy |
| VANGUARD GROUP INC | 2,069,423 | 2,043,947 | -25,476 | 0.00 | 0.00 | -0.00 | sell |
| Portolan Capital Management, LLC | 1,162,829 | 1,918,030 | +755,201 | 2.09 | 2.09 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 824,712 | 1,309,221 | +484,509 | 0.01 | 0.00 | -0.00 | buy |
| Granahan Investment Management, LLC | 671,779 | 1,129,491 | +457,712 | 0.56 | 0.60 | +0.04 | buy |
| GILDER GAGNON HOWE & CO LLC | 1,173,918 | 932,799 | -241,119 | 0.35 | 0.15 | -0.19 | sell |
| DIMENSIONAL FUND ADVISORS LP | 996,636 | 907,494 | -89,142 | 0.01 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 798,968 | 840,436 | +41,468 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,265,195 | 834,847 | -1,430,348 | 0.05 | 0.01 | -0.04 | sell |
| STATE STREET CORP | 815,487 | 818,393 | +2,906 | 0.00 | 0.00 | -0.00 | buy |
| ASHFORD CAPITAL MANAGEMENT INC | 831,535 | 771,305 | -60,230 | 2.65 | 1.38 | -1.27 | sell |
| Invesco Ltd. | 810,532 | 737,222 | -73,310 | 0.00 | 0.00 | -0.00 | sell |
| EASTERLY INVESTMENT PARTNERS LLC | 78,734 | 692,746 | +614,012 | 0.14 | 0.80 | +0.66 | buy |
| EMERALD ADVISERS, LLC | 705,447 | 680,987 | -24,460 | 0.67 | 0.38 | -0.29 | sell |
| BAILLIE GIFFORD & CO | 623,355 | 633,460 | +10,105 | 0.01 | 0.01 | -0.00 | buy |
| Tikvah Management LLC | 571,619 | 571,619 | 0 | 4.22 | 2.46 | -1.76 | hold |
| EMERALD MUTUAL FUND ADVISERS TRUST | 558,841 | 558,841 | 0 | 0.69 | 0.39 | -0.30 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 340,726 | 520,270 | +179,544 | 0.00 | 0.00 | -0.00 | buy |
| Pier Capital, LLC | 278,491 | 414,542 | +136,051 | 0.90 | 0.81 | -0.09 | buy |
| PURA VIDA INVESTMENTS, LLC | 375,985 | 409,334 | +33,349 | 6.03 | 6.54 | +0.51 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 425,386 | 384,600 | -40,786 | 0.02 | 0.01 | -0.01 | sell |
| NORTHERN TRUST CORP | 358,405 | 346,848 | -11,557 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 315,383 | 328,519 | +13,136 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 236,731 | 312,022 | +75,291 | 0.00 | 0.00 | -0.00 | buy |
| RWA WEALTH PARTNERS, LLC | 293,203 | 293,203 | 0 | 0.09 | 0.05 | -0.04 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 181,651 | 280,000 | +98,349 | 0.12 | 0.11 | -0.01 | buy |
| Blue Water Life Science Advisors, LP | 309,093 | 278,393 | -30,700 | 6.85 | 3.58 | -3.27 | sell |
| PLATINUM INVESTMENT MANAGEMENT LTD | 217,442 | 277,636 | +60,194 | 0.21 | 0.15 | -0.06 | buy |
| Russell Investments Group, Ltd. | 18,569 | 276,890 | +258,321 | 0.00 | 0.01 | +0.01 | buy |
| Assenagon Asset Management S.A. | 0 | 256,567 | +256,567 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 61,789 | 234,751 | +172,962 | 0.00 | 0.00 | +0.00 | buy |
| Williams Jones Wealth Management, LLC. | 56,337 | 222,145 | +165,808 | 0.02 | 0.04 | +0.02 | buy |
| ROYCE & ASSOCIATES LP | 215,948 | 215,948 | 0 | 0.05 | 0.03 | -0.02 | hold |
| ENVESTNET ASSET MANAGEMENT INC | 8,880 | 209,731 | +200,851 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 299,746 | 194,747 | -104,999 | 0.01 | 0.00 | -0.01 | sell |
| MORGAN STANLEY | 215,832 | 186,486 | -29,346 | 0.00 | 0.00 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 176,112 | 176,377 | +265 | 0.51 | 0.32 | -0.19 | buy |
| JPMORGAN CHASE & CO | 93,263 | 170,084 | +76,821 | 0.00 | 0.00 | -0.00 | buy |
| PICTON MAHONEY ASSET MANAGEMENT | 86,092 | 165,076 | +78,984 | 0.09 | 0.09 | +0.01 | buy |
| BRIDGER MANAGEMENT, LLC | 154,900 | 154,900 | 0 | 1.65 | 1.05 | -0.59 | hold |
| FULLER & THALER ASSET MANAGEMENT, INC. | 158,305 | 152,405 | -5,900 | 0.02 | 0.01 | -0.01 | sell |
| AQR CAPITAL MANAGEMENT LLC | 147,501 | 147,990 | +489 | 0.01 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 31,931 | 142,317 | +110,386 | 0.00 | 0.00 | +0.00 | buy |
| MARATHON CAPITAL MANAGEMENT | 119,135 | 137,560 | +18,425 | 0.67 | 0.46 | -0.21 | buy |
| Bank of New York Mellon Corp | 115,705 | 132,100 | +16,395 | 0.00 | 0.00 | -0.00 | buy |
| Valmark Advisers, Inc. | 82,913 | 113,023 | +30,110 | 0.03 | 0.03 | -0.01 | buy |
| PRUDENTIAL FINANCIAL INC | 286,513 | 105,288 | -181,225 | 0.01 | 0.00 | -0.01 | sell |
| BANK OF AMERICA CORP /DE/ | 105,793 | 103,014 | -2,779 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 48,541 | 102,801 | +54,260 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 51,736 | 89,537 | +37,801 | 0.00 | 0.00 | -0.00 | buy |
| ROYAL BANK OF CANADA | 20,189 | 86,048 | +65,859 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 85,019 | 85,019 | 0 | 0.25 | 0.16 | -0.10 | hold |
| HARBOR CAPITAL ADVISORS, INC. | 9,623 | 83,941 | +74,318 | 0.03 | 0.08 | +0.05 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 471,000 | 80,000 | -391,000 | 0.07 | 0.01 | -0.06 | sell |
| ALGERT GLOBAL LLC | 0 | 78,337 | +78,337 | 0.00 | 0.03 | +0.03 | buy |
| Swiss National Bank | 70,300 | 71,500 | +1,200 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 172,548 | 70,248 | -102,300 | 0.01 | 0.00 | -0.01 | sell |
| Aberdeen Group plc | 18,837 | 63,117 | +44,280 | 0.00 | 0.00 | +0.00 | buy |
| Clarius Group, LLC | 62,060 | 62,060 | 0 | 0.10 | 0.06 | -0.04 | hold |
| RHUMBLINE ADVISERS | 67,556 | 60,444 | -7,112 | 0.00 | 0.00 | -0.00 | sell |
| Exome Asset Management LLC | 59,650 | 59,650 | 0 | 1.20 | 0.70 | -0.50 | hold |
| Bulltick Wealth Management, LLC | 0 | 59,500 | +59,500 | 0.00 | 0.22 | +0.22 | buy |
| FRANKLIN RESOURCES INC | 54,351 | 56,394 | +2,043 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 49,027 | 56,145 | +7,118 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 44,096 | 55,205 | +11,109 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 0 | 49,795 | +49,795 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 47,394 | 48,617 | +1,223 | 0.00 | 0.00 | -0.00 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 93,211 | 46,898 | -46,313 | 0.02 | 0.01 | -0.01 | sell |
| Resona Asset Management Co.,Ltd. | 46,839 | 45,182 | -1,657 | 0.01 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 39,916 | 44,143 | +4,227 | 0.00 | 0.00 | -0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 41,098 | 40,495 | -603 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 37,406 | 37,406 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Schonfeld Strategic Advisors LLC | 78,200 | 37,400 | -40,800 | 0.01 | 0.00 | -0.01 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 35,906 | 35,420 | -486 | 0.00 | 0.00 | -0.00 | sell |
| JUPITER ASSET MANAGEMENT LTD | 46,889 | 33,721 | -13,168 | 0.01 | 0.00 | -0.01 | sell |
| Nebula Research & Development LLC | 14,421 | 33,666 | +19,245 | 0.07 | 0.07 | -0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 48,155 | 33,512 | -14,643 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 27,649 | +27,649 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 25,800 | +25,800 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 37,713 | 25,118 | -12,595 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 68,281 | 24,853 | -43,428 | 0.01 | 0.00 | -0.01 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 26,824 | 24,397 | -2,427 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 0 | 23,233 | +23,233 | 0.00 | 0.03 | +0.03 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 21,461 | +21,461 | 0.00 | 0.00 | +0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 10,788 | 21,428 | +10,640 | 0.05 | 0.05 | +0.00 | buy |
| UBS Group AG | 38,359 | 21,169 | -17,190 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 11,711 | 20,329 | +8,618 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 9,112 | 20,263 | +11,151 | 0.01 | 0.01 | +0.00 | buy |
| Ashton Thomas Private Wealth, LLC | 20,100 | 20,100 | 0 | 0.03 | 0.01 | -0.01 | hold |
| MetLife Investment Management, LLC | 17,799 | 19,680 | +1,881 | 0.00 | 0.00 | -0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 19,497 | 19,105 | -392 | 0.03 | 0.02 | -0.01 | sell |
| Empire Financial Management Company, LLC | 18,750 | 18,750 | 0 | 0.15 | 0.08 | -0.06 | hold |
| STRS OHIO | 18,700 | 18,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Graham Capital Management, L.P. | 17,179 | 18,401 | +1,222 | 0.01 | 0.01 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 39,148 | 17,911 | -21,237 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 0 | 17,761 | +17,761 | 0.00 | 0.00 | +0.00 | buy |
| Janney Capital Management LLC | 11,001 | 17,623 | +6,622 | 0.02 | 0.02 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 20,191 | 16,941 | -3,250 | 0.00 | 0.00 | -0.00 | sell |
| CIBC Asset Management Inc | 0 | 15,876 | +15,876 | 0.00 | 0.00 | +0.00 | buy |
| Moors & Cabot, Inc. | 11,823 | 14,881 | +3,058 | 0.02 | 0.01 | -0.00 | buy |