| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| AMERIPRISE FINANCIAL INC | 3,715,238 | 4,236,877 | +521,639 | 0.01 | 0.01 | +0.00 | buy |
| Portolan Capital Management, LLC | 2,963,397 | 3,633,622 | +670,225 | 1.47 | 1.52 | +0.05 | buy |
| BlackRock, Inc. | 3,070,115 | 2,924,699 | -145,416 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,525,679 | 2,528,950 | +3,271 | 0.00 | 0.00 | -0.00 | buy |
| Kent Lake PR LLC | 2,924,903 | 2,301,000 | -623,903 | 8.79 | 6.75 | -2.04 | sell |
| Invenomic Capital Management LP | 902,043 | 1,144,904 | +242,861 | 0.30 | 0.43 | +0.13 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,106,063 | 1,127,981 | +21,918 | 0.02 | 0.02 | -0.00 | buy |
| EASTERLY INVESTMENT PARTNERS LLC | 1,325,620 | 1,083,635 | -241,985 | 0.72 | 0.52 | -0.20 | sell |
| Blue Water Life Science Advisors, LP | 372,175 | 957,747 | +585,572 | 2.40 | 5.04 | +2.64 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 865,870 | 887,080 | +21,210 | 0.00 | 0.00 | -0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 841,333 | 803,735 | -37,598 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 596,049 | 771,440 | +175,391 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 44,506 | 767,801 | +723,295 | 0.00 | 0.01 | +0.01 | buy |
| STATE STREET CORP | 761,308 | 764,855 | +3,547 | 0.00 | 0.00 | -0.00 | buy |
| Williams Jones Wealth Management, LLC. | 513,489 | 676,014 | +162,525 | 0.04 | 0.05 | +0.01 | buy |
| BAILLIE GIFFORD & CO | 600,812 | 600,812 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Trium Capital LLP | 559,500 | 586,425 | +26,925 | 1.48 | 0.97 | -0.51 | buy |
| Parkman Healthcare Partners LLC | 0 | 515,992 | +515,992 | 0.00 | 0.40 | +0.40 | buy |
| MARSHALL WACE, LLP | 0 | 444,191 | +444,191 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 606,787 | 424,659 | -182,128 | 0.01 | 0.00 | -0.00 | sell |
| Aberdeen Group plc | 268,717 | 420,856 | +152,139 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 1,114,978 | 384,951 | -730,027 | 0.00 | 0.00 | -0.00 | sell |
| SCS Capital Management LLC | 354,339 | 354,339 | 0 | 0.03 | 0.03 | -0.00 | hold |
| Schonfeld Strategic Advisors LLC | 0 | 325,677 | +325,677 | 0.00 | 0.02 | +0.02 | buy |
| NORTHERN TRUST CORP | 323,111 | 321,030 | -2,081 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 292,805 | 298,989 | +6,184 | 0.00 | 0.00 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 128,008 | 289,759 | +161,751 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 26,496 | 280,578 | +254,082 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 288,081 | 260,501 | -27,580 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 349,696 | 253,820 | -95,876 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 136,015 | 242,689 | +106,674 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 500,398 | 231,601 | -268,797 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 170,745 | 221,694 | +50,949 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 158,532 | +158,532 | 0.00 | 0.02 | +0.02 | buy |
| JANE STREET GROUP, LLC | 58,313 | 139,964 | +81,651 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 44,380 | 138,737 | +94,357 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 13,448 | 136,448 | +123,000 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 105,457 | 126,641 | +21,184 | 0.01 | 0.01 | -0.00 | buy |
| FMR LLC | 97,940 | 126,632 | +28,692 | 0.00 | 0.00 | +0.00 | buy |
| Empire Financial Management Company, LLC | 50,000 | 123,980 | +73,980 | 0.10 | 0.24 | +0.14 | buy |
| Cubist Systematic Strategies, LLC | 287,231 | 118,043 | -169,188 | 0.02 | 0.01 | -0.02 | sell |
| Bank of New York Mellon Corp | 103,746 | 111,953 | +8,207 | 0.00 | 0.00 | +0.00 | buy |
| Valmark Advisers, Inc. | 244,854 | 105,382 | -139,472 | 0.02 | 0.01 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 202,921 | 103,200 | -99,721 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 98,990 | 88,259 | -10,731 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 79,130 | 86,215 | +7,085 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 54,861 | 78,980 | +24,119 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 54,194 | 75,196 | +21,002 | 0.00 | 0.00 | +0.00 | buy |
| Boussard & Gavaudan Investment Management LLP | 71,671 | 71,671 | 0 | 0.07 | 0.05 | -0.03 | hold |
| Nuveen, LLC | 415,378 | 71,455 | -343,923 | 0.00 | 0.00 | -0.00 | sell |
| Graypoint LLC | 65,000 | 65,000 | 0 | 0.03 | 0.02 | -0.00 | hold |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 56,267 | 64,326 | +8,059 | 0.00 | 0.00 | +0.00 | buy |
| Clarius Group, LLC | 62,060 | 62,060 | 0 | 0.03 | 0.02 | -0.00 | hold |
| BANK OF AMERICA CORP /DE/ | 137,395 | 61,801 | -75,594 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 56,535 | 60,629 | +4,094 | 0.00 | 0.00 | +0.00 | buy |
| Mount Lucas Management LP | 43,837 | 60,000 | +16,163 | 0.13 | 0.19 | +0.06 | buy |
| XTX Topco Ltd | 23,017 | 56,024 | +33,007 | 0.01 | 0.02 | +0.01 | buy |
| PDT Partners, LLC | 0 | 47,668 | +47,668 | 0.00 | 0.02 | +0.02 | buy |
| ALLIANCEBERNSTEIN L.P. | 36,980 | 44,480 | +7,500 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 10,300 | 41,964 | +31,664 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 37,934 | 39,599 | +1,665 | 0.00 | 0.00 | -0.00 | buy |
| CREDIT INDUSTRIEL ET COMMERCIAL | 35,000 | 35,000 | 0 | 0.04 | 0.04 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 186,886 | 34,410 | -152,476 | 0.00 | 0.00 | -0.00 | sell |
| Janney Capital Management LLC | 35,120 | 32,360 | -2,760 | 0.02 | 0.01 | -0.00 | sell |
| Quantbot Technologies LP | 11,272 | 31,864 | +20,592 | 0.00 | 0.01 | +0.00 | buy |
| HSBC HOLDINGS PLC | 31,133 | 29,949 | -1,184 | 0.00 | 0.00 | -0.00 | sell |
| Nebula Research & Development LLC | 35,965 | 29,145 | -6,820 | 0.02 | 0.02 | -0.01 | sell |
| DEUTSCHE BANK AG\ | 30,851 | 24,321 | -6,530 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 23,983 | 23,830 | -153 | 0.00 | 0.00 | +0.00 | sell |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 0 | 21,297 | +21,297 | 0.00 | 0.07 | +0.07 | buy |
| OSAIC HOLDINGS, INC. | 19,103 | 20,499 | +1,396 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 21,380 | 20,444 | -936 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 18,015 | 17,915 | -100 | 0.00 | 0.00 | -0.00 | sell |
| PEDDOCK CAPITAL ADVISORS, LLC | 0 | 17,602 | +17,602 | 0.00 | 0.03 | +0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 23,478 | 16,893 | -6,585 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 21,010 | 16,884 | -4,126 | 0.01 | 0.01 | -0.00 | sell |
| Squarepoint Ops LLC | 16,522 | 15,372 | -1,150 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 10,694 | 15,024 | +4,330 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 7,215 | 14,814 | +7,599 | 0.01 | 0.01 | +0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 14,505 | +14,505 | 0.00 | 0.00 | +0.00 | buy |
| Moors & Cabot, Inc. | 32,453 | 14,452 | -18,001 | 0.01 | 0.00 | -0.01 | sell |
| Allspring Global Investments Holdings, LLC | 15,074 | 14,242 | -832 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 13,534 | 13,571 | +37 | 0.00 | 0.00 | -0.00 | buy |
| Post Resch Tallon Group Inc. | 12,950 | 12,175 | -775 | 0.09 | 0.08 | -0.01 | sell |
| HUB Investment Partners, LLC | 0 | 12,161 | +12,161 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 55,713 | 12,116 | -43,597 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 10,154 | 10,154 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 0 | 10,109 | +10,109 | 0.00 | 0.00 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 10,091 | 10,091 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 10,062 | 10,062 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Versant Capital Management, Inc | 1,317 | 8,397 | +7,080 | 0.00 | 0.01 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 6,501 | 6,501 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Tower Research Capital LLC (TRC) | 1,984 | 5,273 | +3,289 | 0.00 | 0.00 | +0.00 | buy |
| DekaBank Deutsche Girozentrale | 4,566 | 4,566 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aquatic Capital Management LLC | 31,019 | 4,276 | -26,743 | 0.01 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 3,475 | 3,475 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NISA INVESTMENT ADVISORS, LLC | 897 | 3,349 | +2,452 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 6,688 | 3,307 | -3,381 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 0 | 3,152 | +3,152 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 10,200 | 3,000 | -7,200 | 0.00 | 0.00 | -0.00 | sell |