| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 3,277,595 | 3,635,411 | +357,816 | 0.00 | 0.00 | +0.00 | buy |
| Blue Water Life Science Advisors, LP | 2,142,147 | 3,474,202 | +1,332,055 | 6.05 | 9.45 | +3.41 | buy |
| First Eagle Investment Management, LLC | 1,300,087 | 2,753,165 | +1,453,078 | 0.01 | 0.02 | +0.01 | buy |
| Portolan Capital Management, LLC | 2,945,823 | 1,899,308 | -1,046,515 | 0.55 | 0.31 | -0.24 | sell |
| AQR CAPITAL MANAGEMENT LLC | 84,132 | 1,343,005 | +1,258,873 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 994,764 | 1,131,377 | +136,613 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 3,542,374 | 987,424 | -2,554,950 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 622,380 | 973,872 | +351,492 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 898,277 | 932,307 | +34,030 | 0.00 | 0.00 | +0.00 | buy |
| Tikvah Management LLC | 571,619 | 571,555 | -64 | 0.62 | 0.75 | +0.13 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 487,600 | +487,600 | 0.00 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 607,856 | 447,688 | -160,168 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 155,655 | 419,050 | +263,395 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 95,528 | 410,252 | +314,724 | 0.02 | 0.11 | +0.09 | buy |
| TUDOR INVESTMENT CORP ET AL | 316,001 | 400,402 | +84,401 | 0.01 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 443,118 | 397,833 | -45,285 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 349,658 | 337,227 | -12,431 | 0.00 | 0.00 | +0.00 | sell |
| Sixth Street Partners Management Company, L.P. | 0 | 310,701 | +310,701 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 345,913 | 310,701 | -35,212 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 376,982 | 281,978 | -95,004 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 71,842 | 232,592 | +160,750 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 229,736 | +229,736 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 111,660 | 228,035 | +116,375 | 0.01 | 0.01 | +0.01 | buy |
| Point72 Asset Management, L.P. | 93,253 | 225,653 | +132,400 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 270,187 | 212,056 | -58,131 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 183,356 | 210,634 | +27,278 | 0.00 | 0.00 | +0.00 | buy |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 169,825 | 170,555 | +730 | 0.25 | 0.25 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 168,620 | +168,620 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 116,216 | 160,887 | +44,671 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 129,024 | 149,158 | +20,134 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 148,618 | +148,618 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 134,403 | 136,876 | +2,473 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 126,363 | 131,900 | +5,537 | 0.00 | 0.00 | +0.00 | buy |
| SCS Capital Management LLC | 120,035 | 120,035 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMERICAN CENTURY COMPANIES INC | 101,810 | 100,463 | -1,347 | 0.00 | 0.00 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 68,372 | 95,626 | +27,254 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 80,200 | +80,200 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 78,083 | +78,083 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 68,226 | 68,226 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Clearstead Advisors, LLC | 124,120 | 62,261 | -61,859 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 0 | 57,319 | +57,319 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 44,480 | 56,780 | +12,300 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 55,217 | +55,217 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 52,065 | 53,557 | +1,492 | 0.00 | 0.00 | +0.00 | buy |
| PEDDOCK CAPITAL ADVISORS, LLC | 52,105 | 52,105 | 0 | 0.04 | 0.04 | +0.00 | hold |
| MILLENNIUM MANAGEMENT LLC | 689,167 | 40,662 | -648,505 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 38,961 | +38,961 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 38,100 | +38,100 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 35,460 | 36,678 | +1,218 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 641,981 | 35,557 | -606,424 | 0.00 | 0.00 | -0.00 | sell |
| IEQ CAPITAL, LLC | 0 | 35,507 | +35,507 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 26,914 | +26,914 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 10,875 | 25,731 | +14,856 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 24,354 | 25,599 | +1,245 | 0.01 | 0.01 | +0.00 | buy |
| MetLife Investment Management, LLC | 22,576 | 24,801 | +2,225 | 0.00 | 0.00 | +0.00 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 24,328 | +24,328 | 0.00 | 0.03 | +0.03 | buy |
| OSAIC HOLDINGS, INC. | 22,816 | 24,176 | +1,360 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 77,871 | 20,816 | -57,055 | 0.04 | 0.02 | -0.02 | sell |
| CITIGROUP INC | 1,962 | 19,713 | +17,751 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 19,580 | 19,655 | +75 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 18,538 | +18,538 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 17,672 | +17,672 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 17,356 | +17,356 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 16,746 | 15,805 | -941 | 0.00 | 0.00 | +0.00 | sell |
| HUB Investment Partners, LLC | 13,661 | 15,734 | +2,073 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 15,471 | +15,471 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 23,800 | 14,807 | -8,993 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 28,430 | 14,700 | -13,730 | 0.00 | 0.00 | -0.00 | sell |
| CAPTRUST FINANCIAL ADVISORS | 0 | 14,301 | +14,301 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 11,412 | 13,788 | +2,376 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 0 | 13,660 | +13,660 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 13,239 | +13,239 | 0.00 | 0.00 | +0.00 | buy |
| PharVision Advisers, LLC | 0 | 13,039 | +13,039 | 0.00 | 1.06 | +1.06 | buy |
| Schonfeld Strategic Advisors LLC | 42,786 | 12,663 | -30,123 | 0.00 | 0.00 | -0.00 | sell |
| Post Resch Tallon Group Inc. | 12,500 | 12,500 | 0 | 0.04 | 0.04 | +0.00 | hold |
| Qube Research & Technologies Ltd | 0 | 11,987 | +11,987 | 0.00 | 0.00 | +0.00 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 0 | 11,294 | +11,294 | 0.00 | 0.00 | +0.00 | buy |
| IMC-Chicago, LLC | 0 | 10,214 | +10,214 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 10,062 | 10,062 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Cresset Asset Management, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 7,558 | +7,558 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 7,224 | +7,224 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 7,127 | +7,127 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 0 | 7,123 | +7,123 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 6,501 | 6,501 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 3,993 | 3,993 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ameritas Investment Partners, Inc. | 3,475 | 3,475 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Tower Research Capital LLC (TRC) | 3,987 | 3,108 | -879 | 0.00 | 0.00 | -0.00 | sell |
| Sachetta, LLC | 0 | 3,000 | +3,000 | 0.00 | 0.01 | +0.01 | buy |
| Allworth Financial LP | 111 | 2,143 | +2,032 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 872 | 1,933 | +1,061 | 0.00 | 0.00 | +0.00 | buy |
| Pinnacle Wealth Planning Services, Inc. | 1,799 | 1,799 | 0 | 0.00 | 0.00 | +0.00 | hold |
| EverSource Wealth Advisors, LLC | 55 | 1,503 | +1,448 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 151 | 1,068 | +917 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Sterling Capital Management LLC | 1,275 | 860 | -415 | 0.00 | 0.00 | -0.00 | sell |
| Wilmington Savings Fund Society, FSB | 800 | 800 | 0 | 0.00 | 0.00 | +0.00 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 771 | 771 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MassMutual Private Wealth & Trust, FSB | 0 | 600 | +600 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,389 | 585 | -1,804 | 0.00 | 0.00 | -0.00 | sell |