| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Eversept Partners, LP | 0 | 5,016,320 | +5,016,320 | 0.00 | 0.57 | +0.57 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,663,300 | 3,500,000 | +1,836,700 | 0.00 | 0.01 | +0.01 | buy |
| MARSHALL WACE, LLP | 1,926,782 | 2,595,599 | +668,817 | 0.00 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 617,216 | 962,825 | +345,609 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,053,773 | 2,285,788 | +232,015 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,296,593 | 1,508,262 | +211,669 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,181,120 | 1,377,584 | +196,464 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 49,122 | 242,841 | +193,719 | 0.01 | 0.05 | +0.04 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 157,915 | +157,915 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,382,428 | 2,520,105 | +137,677 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 137,012 | +137,012 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 380,000 | 500,000 | +120,000 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 115,864 | 212,638 | +96,774 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 76,599 | +76,599 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 60,551 | +60,551 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Wealth | 0 | 45,930 | +45,930 | 0.00 | 0.00 | +0.00 | buy |
| Simplicity Wealth,LLC | 0 | 44,011 | +44,011 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 40,000 | +40,000 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 35,868 | +35,868 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 21,001 | 55,985 | +34,984 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 33,898 | +33,898 | 0.00 | 0.00 | +0.00 | buy |
| Freedom Investment Management, Inc. | 0 | 29,197 | +29,197 | 0.00 | 0.00 | +0.00 | buy |
| Atom Investors LP | 216,690 | 244,397 | +27,707 | 0.03 | 0.05 | +0.01 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | 25,406 | +25,406 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 23,500 | +23,500 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 28,431 | 47,307 | +18,876 | 0.00 | 0.01 | +0.01 | buy |
| Woodline Partners LP | 116,718 | 134,112 | +17,394 | 0.00 | 0.00 | +0.00 | buy |
| Winthrop Advisory Group LLC | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 81,736 | 91,091 | +9,355 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 400,000 | 409,355 | +9,355 | 0.09 | 0.17 | +0.07 | buy |
| HSBC HOLDINGS PLC | 45,290 | 53,563 | +8,273 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 87,113 | 95,091 | +7,978 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 13,800 | 20,800 | +7,000 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 30,473 | 37,132 | +6,659 | 0.00 | 0.00 | +0.00 | buy |
| METROPOLITAN LIFE INSURANCE CO/NY | 0 | 6,231 | +6,231 | 0.00 | 0.00 | +0.00 | buy |
| Bleakley Financial Group, LLC | 37,938 | 44,011 | +6,073 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 138,107 | 144,028 | +5,921 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 268,286 | 273,808 | +5,522 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 71,224 | 76,317 | +5,093 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,769,184 | 1,773,758 | +4,574 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 3,101,399 | 3,105,069 | +3,670 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 16,432 | 18,924 | +2,492 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 227,445 | 229,924 | +2,479 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 19,373 | 21,150 | +1,777 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 31,442 | 33,165 | +1,723 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 18,746 | 20,348 | +1,602 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 0 | 1,479 | +1,479 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 1,242 | +1,242 | 0.00 | 0.00 | +0.00 | buy |
| Providence Capital Advisors, LLC | 0 | 312 | +312 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 202 | +202 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| Avior Wealth Management, LLC | 0 | 22 | +22 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 3 | 12 | +9 | 0.00 | 0.00 | 0.00 | buy |
| Ameritas Investment Partners, Inc. | 6,194 | 6,194 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 192,810 | 192,810 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Palo Alto Investors LP | 5,102,193 | 5,102,193 | 0 | 0.40 | 0.87 | +0.47 | hold |
| Janney Montgomery Scott LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6 | 6 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DAFNA Capital Management LLC | 192,678 | 192,678 | 0 | 0.04 | 0.07 | +0.03 | hold |
| Diversified Trust Co | 18,580 | 18,580 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allworth Financial LP | 500 | 500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Birchview Capital, LP | 469,832 | 469,832 | 0 | 0.32 | 0.58 | +0.26 | hold |
| Engineers Gate Manager LP | 28,700 | 28,700 | 0 | 0.00 | 0.00 | +0.00 | hold |
| C WorldWide Group Holding A/S | 1,500,000 | 1,500,000 | 0 | 0.02 | 0.03 | +0.01 | hold |
| Founders Capital Management | 2,000 | 2,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| West Branch Capital LLC | 48 | 48 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Altium Capital Management LLC | 740,000 | 740,000 | 0 | 0.44 | 0.50 | +0.06 | hold |
| Avidity Partners Management LP | 8,298,570 | 8,298,570 | 0 | 0.27 | 0.45 | +0.17 | hold |
| Banque Cantonale Vaudoise | 25,000 | 25,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Snowden Capital Advisors LLC | 11,000 | 11,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| KENNEDY INVESTMENT GROUP | 35,000 | 35,000 | 0 | 0.02 | 0.03 | +0.01 | hold |
| Bruce G. Allen Investments, LLC | 507 | 507 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Kelly Financial Services LLC | 250 | 250 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MB, LEVIS & ASSOCIATES, LLC | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 13,735 | 13,735 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HARBOUR INVESTMENTS, INC. | 1,300 | 1,300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 309,909 | 309,909 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Corient Private Wealth LLC | 14,000 | 13,900 | -100 | 0.00 | 0.00 | +0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 56,295 | 55,816 | -479 | 0.00 | 0.00 | +0.00 | sell |
| AdvisorNet Financial, Inc | 700 | 200 | -500 | 0.00 | 0.00 | -0.00 | sell |
| Advisory Services Network, LLC | 500 | 0 | -500 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 28,471 | 27,969 | -502 | 0.00 | 0.00 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 1,327,008 | 1,324,977 | -2,031 | 0.00 | 0.00 | +0.00 | sell |
| TD Waterhouse Canada Inc. | 2,060 | 0 | -2,060 | 0.00 | 0.00 | -0.00 | sell |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 29,422 | 27,015 | -2,407 | 0.00 | 0.00 | +0.00 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 561,955 | 558,466 | -3,489 | 0.15 | 0.24 | +0.09 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 391,540 | 387,520 | -4,020 | 0.00 | 0.00 | +0.00 | sell |
| Cubist Systematic Strategies, LLC | 4,684 | 0 | -4,684 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 24,815 | 19,615 | -5,200 | 0.00 | 0.00 | +0.00 | sell |
| Russell Investments Group, Ltd. | 6,519 | 0 | -6,519 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 45,471 | 38,802 | -6,669 | 0.00 | 0.00 | +0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 18,642 | 11,387 | -7,255 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 19,586 | 10,208 | -9,378 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 10,007 | 0 | -10,007 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 497,202 | 487,060 | -10,142 | 0.00 | 0.00 | +0.00 | sell |
| Orion Porfolio Solutions, LLC | 10,965 | 0 | -10,965 | 0.00 | 0.00 | -0.00 | sell |
| Bayesian Capital Management, LP | 11,100 | 0 | -11,100 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 11,600 | 0 | -11,600 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 11,616 | 0 | -11,616 | 0.00 | 0.00 | -0.00 | sell |