KARYOPHARM THERAPEUTICS INC
| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 421,322 | 1,806,322 | +1,385,000 | 0.00 | 0.02 | +0.01 | buy |
| Catalio Capital Management, LP | 142,984 | 897,709 | +754,725 | 0.19 | 1.04 | +0.86 | buy |
| Avidity Partners Management LP | 134,566 | 463,741 | +329,175 | 0.29 | 0.52 | +0.24 | buy |
| Ikarian Capital, LLC | 544,554 | 733,435 | +188,881 | 0.52 | 0.58 | +0.07 | buy |
| ADAR1 Capital Management, LLC | 50,000 | 136,736 | +86,736 | 0.03 | 0.05 | +0.02 | buy |
| T. Rowe Price Investment Management, Inc. | 1,491,409 | 1,542,090 | +50,681 | 0.01 | 0.01 | -0.00 | buy |
| Boxer Capital Management, LLC | 252,536 | 302,536 | +50,000 | 0.41 | 0.22 | -0.19 | buy |
| SILVERBACK ASSET MANAGEMENT LLC | 40,000 | 65,000 | +25,000 | 0.04 | 0.07 | +0.03 | buy |
| DAFNA Capital Management LLC | 51,000 | 45,800 | -5,200 | 0.09 | 0.06 | -0.03 | sell |
| Affinity Asset Advisors, LLC | 889,575 | 500,000 | -389,575 | 0.47 | 0.16 | -0.31 | sell |