| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 8,338,401 | 7,654,482 | -683,919 | 0.00 | 0.00 | -0.00 | sell |
| Palo Alto Investors LP | 5,102,193 | 5,102,193 | 0 | 0.87 | 0.51 | -0.36 | hold |
| Eversept Partners, LP | 5,016,320 | 4,987,180 | -29,140 | 0.57 | 0.33 | -0.23 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,500,000 | 4,319,842 | +819,842 | 0.01 | 0.01 | -0.00 | buy |
| CITADEL ADVISORS LLC | 3,105,069 | 3,101,399 | -3,670 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 2,595,599 | 2,580,863 | -14,736 | 0.01 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 1,508,262 | 2,290,434 | +782,172 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,773,758 | 2,274,195 | +500,437 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,185,879 | 2,092,426 | +906,547 | 0.00 | 0.00 | -0.00 | buy |
| Avidity Partners Management LP | 8,298,570 | 2,018,500 | -6,280,070 | 0.45 | 0.07 | -0.37 | sell |
| JANE STREET GROUP, LLC | 171,650 | 1,549,976 | +1,378,326 | 0.00 | 0.00 | +0.00 | buy |
| C WorldWide Group Holding A/S | 1,500,000 | 1,500,000 | 0 | 0.03 | 0.01 | -0.01 | hold |
| Opaleye Management Inc. | 0 | 1,425,000 | +1,425,000 | 0.00 | 0.28 | +0.28 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,520,105 | 1,311,536 | -1,208,569 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 1,377,584 | 1,275,859 | -101,725 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 1,324,977 | 1,268,777 | -56,200 | 0.00 | 0.00 | -0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 0 | 1,196,792 | +1,196,792 | 0.00 | 0.02 | +0.02 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 722,327 | 1,102,391 | +380,064 | 0.03 | 0.03 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 1,299,151 | 983,417 | -315,734 | 0.16 | 0.06 | -0.10 | sell |
| BARCLAYS PLC | 892,815 | 873,274 | -19,541 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 958,805 | 870,167 | -88,638 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 962,825 | 844,112 | -118,713 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 906,800 | 756,227 | -150,573 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 125,826 | 748,020 | +622,194 | 0.00 | 0.00 | +0.00 | buy |
| Altium Capital Management LLC | 740,000 | 740,000 | 0 | 0.50 | 0.27 | -0.23 | hold |
| Cubist Systematic Strategies, LLC | 0 | 568,975 | +568,975 | 0.00 | 0.01 | +0.01 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 558,466 | 558,466 | 0 | 0.24 | 0.12 | -0.12 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 534,485 | +534,485 | 0.00 | 0.58 | +0.58 | buy |
| MACQUARIE GROUP LTD | 500,000 | 505,684 | +5,684 | 0.00 | 0.00 | -0.00 | buy |
| Birchview Capital, LP | 469,832 | 469,832 | 0 | 0.58 | 0.38 | -0.20 | hold |
| STATE STREET CORP | 2,285,788 | 453,810 | -1,831,978 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 76,599 | 443,474 | +366,875 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 410,954 | +410,954 | 0.00 | 0.02 | +0.02 | buy |
| Ikarian Capital, LLC | 409,355 | 409,355 | 0 | 0.17 | 0.11 | -0.06 | hold |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 387,520 | 354,020 | -33,500 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 157,915 | 298,685 | +140,770 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 273,808 | 293,213 | +19,405 | 0.00 | 0.00 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 189,500 | 264,500 | +75,000 | 0.01 | 0.01 | -0.00 | buy |
| Atom Investors LP | 244,397 | 261,847 | +17,450 | 0.05 | 0.02 | -0.02 | buy |
| Centiva Capital, LP | 0 | 203,600 | +203,600 | 0.00 | 0.01 | +0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 194,168 | +194,168 | 0.00 | 0.00 | +0.00 | buy |
| DAFNA Capital Management LLC | 192,678 | 192,678 | 0 | 0.07 | 0.04 | -0.03 | hold |
| Bank of New York Mellon Corp | 487,060 | 166,315 | -320,745 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 165,318 | +165,318 | 0.00 | 0.03 | +0.03 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 212,638 | 162,178 | -50,460 | 0.01 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 18,924 | 162,027 | +143,103 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 147,536 | +147,536 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 254,933 | 140,678 | -114,255 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 242,841 | 140,576 | -102,265 | 0.05 | 0.01 | -0.04 | sell |
| Woodline Partners LP | 134,112 | 134,112 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Qube Research & Technologies Ltd | 0 | 106,470 | +106,470 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 95,091 | 97,100 | +2,009 | 0.00 | 0.00 | -0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 91,091 | 91,091 | 0 | 0.00 | 0.00 | -0.00 | hold |
| State of Wyoming | 47,307 | 82,685 | +35,378 | 0.01 | 0.01 | -0.00 | buy |
| Verition Fund Management LLC | 0 | 68,932 | +68,932 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 57,600 | +57,600 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 53,563 | 53,091 | -472 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 309,909 | 51,000 | -258,909 | 0.00 | 0.00 | -0.00 | sell |
| Simplicity Wealth,LLC | 44,011 | 49,160 | +5,149 | 0.00 | 0.00 | -0.00 | buy |
| Bleakley Financial Group, LLC | 44,011 | 49,160 | +5,149 | 0.00 | 0.00 | -0.00 | buy |
| Focus Partners Wealth | 45,930 | 45,930 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Invesco Ltd. | 27,969 | 40,511 | +12,542 | 0.00 | 0.00 | -0.00 | buy |
| SEI INVESTMENTS CO | 40,000 | 40,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Freedom Investment Management, Inc. | 29,197 | 38,326 | +9,129 | 0.00 | 0.00 | -0.00 | buy |
| Baird Financial Group, Inc. | 20,800 | 36,800 | +16,000 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 35,939 | +35,939 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 35,184 | +35,184 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY INVESTMENT GROUP | 35,000 | 35,000 | 0 | 0.03 | 0.02 | -0.01 | hold |
| Redwood Wealth Management Group, LLC | 0 | 34,030 | +34,030 | 0.00 | 0.02 | +0.02 | buy |
| Engineers Gate Manager LP | 28,700 | 28,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Catalyst Funds Management Pty Ltd | 0 | 28,600 | +28,600 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 0 | 26,798 | +26,798 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 25,406 | 25,206 | -200 | 0.00 | 0.00 | -0.00 | sell |
| Banque Cantonale Vaudoise | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Neuberger Berman Group LLC | 0 | 22,951 | +22,951 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 22,562 | +22,562 | 0.00 | 0.00 | +0.00 | buy |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 0 | 21,941 | +21,941 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 144,028 | 16,431 | -127,597 | 0.00 | 0.00 | -0.00 | sell |
| Paloma Partners Management Co | 0 | 15,435 | +15,435 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 20,348 | 15,170 | -5,178 | 0.00 | 0.00 | -0.00 | sell |
| Winthrop Advisory Group LLC | 15,000 | 15,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 13,993 | +13,993 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 13,691 | 13,866 | +175 | 0.00 | 0.00 | -0.00 | buy |
| Corient Private Wealth LLC | 13,900 | 13,600 | -300 | 0.00 | 0.00 | -0.00 | sell |
| BLB&B Advisors, LLC | 0 | 11,150 | +11,150 | 0.00 | 0.00 | +0.00 | buy |
| Snowden Capital Advisors LLC | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Scientech Research LLC | 0 | 10,950 | +10,950 | 0.00 | 0.00 | +0.00 | buy |
| Janney Montgomery Scott LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CWM, LLC | 12 | 6,248 | +6,236 | 0.00 | 0.00 | +0.00 | buy |
| Quent Capital, LLC | 0 | 3,489 | +3,489 | 0.00 | 0.00 | +0.00 | buy |
| Founders Capital Management | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MB, LEVIS & ASSOCIATES, LLC | 1,500 | 1,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HARBOUR INVESTMENTS, INC. | 1,300 | 1,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Activest Wealth Management | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 21,150 | 955 | -20,195 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 0 | 538 | +538 | 0.00 | 0.00 | +0.00 | buy |
| Bruce G. Allen Investments, LLC | 507 | 507 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Allworth Financial LP | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Providence Capital Advisors, LLC | 312 | 312 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Kelly Financial Services LLC | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |