| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 0 | 1,425,000 | +1,425,000 | 0.00 | 0.28 | +0.28 | buy |
| JANE STREET GROUP, LLC | 171,650 | 1,549,976 | +1,378,326 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 0 | 1,196,792 | +1,196,792 | 0.00 | 0.02 | +0.02 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,185,879 | 2,092,426 | +906,547 | 0.00 | 0.00 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,500,000 | 4,319,842 | +819,842 | 0.01 | 0.01 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,508,262 | 2,290,434 | +782,172 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 125,826 | 748,020 | +622,194 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 568,975 | +568,975 | 0.00 | 0.01 | +0.01 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 534,485 | +534,485 | 0.00 | 0.58 | +0.58 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,773,758 | 2,274,195 | +500,437 | 0.00 | 0.00 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 410,954 | +410,954 | 0.00 | 0.02 | +0.02 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 722,327 | 1,102,391 | +380,064 | 0.03 | 0.03 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 76,599 | 443,474 | +366,875 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 203,600 | +203,600 | 0.00 | 0.01 | +0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 194,168 | +194,168 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 165,318 | +165,318 | 0.00 | 0.03 | +0.03 | buy |
| HRT FINANCIAL LP | 0 | 147,536 | +147,536 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 18,924 | 162,027 | +143,103 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 157,915 | 298,685 | +140,770 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 106,470 | +106,470 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 189,500 | 264,500 | +75,000 | 0.01 | 0.01 | -0.00 | buy |
| Verition Fund Management LLC | 0 | 68,932 | +68,932 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 57,600 | +57,600 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 35,939 | +35,939 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 47,307 | 82,685 | +35,378 | 0.01 | 0.01 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 35,184 | +35,184 | 0.00 | 0.00 | +0.00 | buy |
| Redwood Wealth Management Group, LLC | 0 | 34,030 | +34,030 | 0.00 | 0.02 | +0.02 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 28,600 | +28,600 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 0 | 26,798 | +26,798 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 0 | 22,951 | +22,951 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 22,562 | +22,562 | 0.00 | 0.00 | +0.00 | buy |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 0 | 21,941 | +21,941 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 273,808 | 293,213 | +19,405 | 0.00 | 0.00 | -0.00 | buy |
| Atom Investors LP | 244,397 | 261,847 | +17,450 | 0.05 | 0.02 | -0.02 | buy |
| Baird Financial Group, Inc. | 20,800 | 36,800 | +16,000 | 0.00 | 0.00 | +0.00 | buy |
| Paloma Partners Management Co | 0 | 15,435 | +15,435 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 13,993 | +13,993 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 27,969 | 40,511 | +12,542 | 0.00 | 0.00 | -0.00 | buy |
| BLB&B Advisors, LLC | 0 | 11,150 | +11,150 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 0 | 10,950 | +10,950 | 0.00 | 0.00 | +0.00 | buy |
| Freedom Investment Management, Inc. | 29,197 | 38,326 | +9,129 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 12 | 6,248 | +6,236 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 500,000 | 505,684 | +5,684 | 0.00 | 0.00 | -0.00 | buy |
| Simplicity Wealth,LLC | 44,011 | 49,160 | +5,149 | 0.00 | 0.00 | -0.00 | buy |
| Bleakley Financial Group, LLC | 44,011 | 49,160 | +5,149 | 0.00 | 0.00 | -0.00 | buy |
| Quent Capital, LLC | 0 | 3,489 | +3,489 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 95,091 | 97,100 | +2,009 | 0.00 | 0.00 | -0.00 | buy |
| Activest Wealth Management | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 538 | +538 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 13,691 | 13,866 | +175 | 0.00 | 0.00 | -0.00 | buy |
| CIBC Private Wealth Group LLC | 50 | 50 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Palo Alto Investors LP | 5,102,193 | 5,102,193 | 0 | 0.87 | 0.51 | -0.36 | hold |
| Janney Montgomery Scott LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DAFNA Capital Management LLC | 192,678 | 192,678 | 0 | 0.07 | 0.04 | -0.03 | hold |
| AdvisorNet Financial, Inc | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Focus Partners Wealth | 45,930 | 45,930 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 91,091 | 91,091 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Allworth Financial LP | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Birchview Capital, LP | 469,832 | 469,832 | 0 | 0.58 | 0.38 | -0.20 | hold |
| Engineers Gate Manager LP | 28,700 | 28,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| C WorldWide Group Holding A/S | 1,500,000 | 1,500,000 | 0 | 0.03 | 0.01 | -0.01 | hold |
| Founders Capital Management | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Providence Capital Advisors, LLC | 312 | 312 | 0 | 0.00 | 0.00 | -0.00 | hold |
| West Branch Capital LLC | 48 | 48 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Winthrop Advisory Group LLC | 15,000 | 15,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Altium Capital Management LLC | 740,000 | 740,000 | 0 | 0.50 | 0.27 | -0.23 | hold |
| Ikarian Capital, LLC | 409,355 | 409,355 | 0 | 0.17 | 0.11 | -0.06 | hold |
| Woodline Partners LP | 134,112 | 134,112 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Banque Cantonale Vaudoise | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SILVERARC CAPITAL MANAGEMENT, LLC | 558,466 | 558,466 | 0 | 0.24 | 0.12 | -0.12 | hold |
| Snowden Capital Advisors LLC | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KENNEDY INVESTMENT GROUP | 35,000 | 35,000 | 0 | 0.03 | 0.02 | -0.01 | hold |
| Bruce G. Allen Investments, LLC | 507 | 507 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Kelly Financial Services LLC | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MB, LEVIS & ASSOCIATES, LLC | 1,500 | 1,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SEI INVESTMENTS CO | 40,000 | 40,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HARBOUR INVESTMENTS, INC. | 1,300 | 1,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6 | 0 | -6 | 0.00 | 0.00 | -0.00 | sell |
| Farther Finance Advisors, LLC | 13 | 0 | -13 | 0.00 | 0.00 | -0.00 | sell |
| Avior Wealth Management, LLC | 22 | 0 | -22 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 202 | 50 | -152 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 25,406 | 25,206 | -200 | 0.00 | 0.00 | -0.00 | sell |
| Corient Private Wealth LLC | 13,900 | 13,600 | -300 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 53,563 | 53,091 | -472 | 0.00 | 0.00 | -0.00 | sell |
| Headlands Technologies LLC | 1,242 | 0 | -1,242 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 1,479 | 0 | -1,479 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 2,478 | 0 | -2,478 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 3,105,069 | 3,101,399 | -3,670 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 20,348 | 15,170 | -5,178 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 6,194 | 0 | -6,194 | 0.00 | 0.00 | -0.00 | sell |
| METROPOLITAN LIFE INSURANCE CO/NY | 6,231 | 0 | -6,231 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 10,208 | 0 | -10,208 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 11,387 | 0 | -11,387 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 13,735 | 0 | -13,735 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 2,595,599 | 2,580,863 | -14,736 | 0.01 | 0.00 | -0.00 | sell |
| Diversified Trust Co | 18,580 | 0 | -18,580 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 892,815 | 873,274 | -19,541 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 19,615 | 0 | -19,615 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 21,150 | 955 | -20,195 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 23,500 | 0 | -23,500 | 0.00 | 0.00 | -0.00 | sell |