| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 315,845 | 2,525,883 | +2,210,038 | 0.00 | 0.02 | +0.02 | buy |
| Woodline Partners LP | 37,343 | 1,089,345 | +1,052,002 | 0.00 | 0.04 | +0.03 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 105,252 | 893,601 | +788,349 | 0.00 | 0.01 | +0.01 | buy |
| GREAT POINT PARTNERS LLC | 0 | 621,894 | +621,894 | 0.00 | 1.44 | +1.44 | buy |
| Walleye Capital LLC | 0 | 491,466 | +491,466 | 0.00 | 0.02 | +0.02 | buy |
| VANGUARD GROUP INC | 1,932,057 | 2,321,006 | +388,949 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 331,799 | +331,799 | 0.00 | 0.00 | +0.00 | buy |
| Nantahala Capital Management, LLC | 2,577,121 | 2,857,982 | +280,861 | 1.05 | 0.98 | -0.07 | buy |
| Integral Health Asset Management, LLC | 250,000 | 500,000 | +250,000 | 0.14 | 0.22 | +0.07 | buy |
| J. Goldman & Co LP | 0 | 232,627 | +232,627 | 0.00 | 0.04 | +0.04 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 343,672 | 554,879 | +211,207 | 0.01 | 0.01 | +0.00 | buy |
| Qube Research & Technologies Ltd | 126,965 | 307,610 | +180,645 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Europe (London) LLP | 0 | 146,932 | +146,932 | 0.00 | 0.04 | +0.04 | buy |
| JANE STREET GROUP, LLC | 0 | 135,963 | +135,963 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 128,668 | +128,668 | 0.00 | 0.06 | +0.06 | buy |
| DIMENSIONAL FUND ADVISORS LP | 57,578 | 185,768 | +128,190 | 0.00 | 0.00 | +0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 123,184 | +123,184 | 0.00 | 0.53 | +0.53 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 439,233 | 526,223 | +86,990 | 0.05 | 0.06 | +0.01 | buy |
| Man Group plc | 0 | 86,640 | +86,640 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 76,000 | +76,000 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 69,724 | +69,724 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 64,133 | +64,133 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 56,573 | +56,573 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 125,472 | 178,572 | +53,100 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 0 | 47,307 | +47,307 | 0.00 | 0.01 | +0.01 | buy |
| ALPS ADVISORS INC | 0 | 46,850 | +46,850 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 34,311 | +34,311 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 398,454 | 432,056 | +33,602 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 31,411 | +31,411 | 0.00 | 0.07 | +0.07 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 491,601 | 517,014 | +25,413 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 39,849 | 64,591 | +24,742 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 49,322 | 69,989 | +20,667 | 0.00 | 0.00 | +0.00 | buy |
| Pale Fire Capital SE | 24,289 | 43,187 | +18,898 | 0.02 | 0.05 | +0.03 | buy |
| Alpine Global Management, LLC | 0 | 11,057 | +11,057 | 0.00 | 0.02 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 13,757 | 22,757 | +9,000 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 13,329 | 19,799 | +6,470 | 0.01 | 0.03 | +0.01 | buy |
| Point72 (DIFC) Ltd | 0 | 3,035 | +3,035 | 0.00 | 0.00 | +0.00 | buy |
| BFSG, LLC | 1,220 | 3,220 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| MML INVESTORS SERVICES, LLC | 11,660 | 13,410 | +1,750 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 1,645 | +1,645 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 10,058 | 10,831 | +773 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,117 | 4,761 | +644 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 11,279,327 | 11,279,327 | 0 | 0.12 | 0.12 | +0.00 | hold |
| CAXTON CORP | 1,318,967 | 1,318,967 | 0 | 26.47 | 38.85 | +12.37 | hold |
| Blackstone Inc. | 1,744,740 | 1,744,740 | 0 | 0.04 | 0.04 | +0.00 | hold |
| NewEdge Advisors, LLC | 3,750 | 3,750 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Vivo Capital, LLC | 2,797,704 | 2,797,704 | 0 | 1.12 | 1.54 | +0.41 | hold |
| Velan Capital Investment Management LP | 800,000 | 800,000 | 0 | 4.21 | 3.38 | -0.83 | hold |
| Aster Capital Management (DIFC) Ltd | 25,078 | 25,078 | 0 | 0.03 | 0.05 | +0.02 | hold |
| Opaleye Management Inc. | 466,563 | 465,000 | -1,563 | 0.38 | 0.40 | +0.02 | sell |
| NORTHERN TRUST CORP | 96,957 | 94,961 | -1,996 | 0.00 | 0.00 | -0.00 | sell |
| nVerses Capital, LLC | 2,800 | 0 | -2,800 | 0.01 | 0.00 | -0.01 | sell |
| Squarepoint Ops LLC | 22,982 | 19,002 | -3,980 | 0.00 | 0.00 | -0.00 | sell |
| Altium Capital Management LLC | 1,700,000 | 1,694,000 | -6,000 | 2.46 | 2.59 | +0.13 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 256,090 | 247,431 | -8,659 | 0.04 | 0.04 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 221,451 | 210,068 | -11,383 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 71,581 | 59,463 | -12,118 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 12,900 | 0 | -12,900 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 104,165 | 85,431 | -18,734 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 26,026 | 0 | -26,026 | 0.01 | 0.00 | -0.01 | sell |
| Jump Financial, LLC | 27,000 | 0 | -27,000 | 0.00 | 0.00 | -0.00 | sell |
| Ikarian Capital, LLC | 887,230 | 857,230 | -30,000 | 1.34 | 1.20 | -0.14 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 1,196,938 | 1,165,895 | -31,043 | 0.95 | 1.06 | +0.11 | sell |
| XTX Topco Ltd | 56,375 | 0 | -56,375 | 0.02 | 0.00 | -0.02 | sell |
| CITADEL ADVISORS LLC | 376,252 | 319,632 | -56,620 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 140,533 | 48,365 | -92,168 | 0.01 | 0.00 | -0.01 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 109,508 | 0 | -109,508 | 0.04 | 0.00 | -0.04 | sell |
| Affinity Asset Advisors, LLC | 1,700,000 | 1,575,000 | -125,000 | 1.28 | 1.21 | -0.07 | sell |
| Informed Momentum Co LLC | 129,858 | 0 | -129,858 | 0.09 | 0.00 | -0.09 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 278,300 | 89,700 | -188,600 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 1,571,705 | 1,359,208 | -212,497 | 1.28 | 1.37 | +0.09 | sell |
| BANK OF AMERICA CORP /DE/ | 362,259 | 90,465 | -271,794 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 344,300 | 71,932 | -272,368 | 0.01 | 0.00 | -0.01 | sell |
| MARSHALL WACE, LLP | 1,128,553 | 843,144 | -285,409 | 0.01 | 0.01 | -0.00 | sell |
| Exome Asset Management LLC | 352,056 | 0 | -352,056 | 1.15 | 0.00 | -1.15 | sell |