| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 0 | 9,180,000 | +9,180,000 | 0.00 | 0.22 | +0.22 | buy |
| Opaleye Management Inc. | 903,442 | 6,287,156 | +5,383,714 | 1.20 | 1.96 | +0.76 | buy |
| BANK OF AMERICA CORP /DE/ | 1,284,962 | 4,325,248 | +3,040,286 | 0.00 | 0.00 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 1,822,728 | 4,506,861 | +2,684,133 | 0.03 | 0.02 | -0.01 | buy |
| FEDERATED HERMES, INC. | 14,034,712 | 16,534,712 | +2,500,000 | 0.23 | 0.07 | -0.17 | buy |
| STATE STREET CORP | 2,091,476 | 3,981,708 | +1,890,232 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 5,004,436 | 6,768,206 | +1,763,770 | 0.00 | 0.00 | -0.00 | buy |
| Vestal Point Capital, LP | 0 | 1,686,000 | +1,686,000 | 0.00 | 0.15 | +0.15 | buy |
| BARCLAYS PLC | 309,696 | 1,911,066 | +1,601,370 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 179,272 | 1,711,194 | +1,531,922 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 109,813 | 1,407,699 | +1,297,886 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 337,920 | 1,516,435 | +1,178,515 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 251,629 | 1,093,925 | +842,296 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 541,487 | 1,304,782 | +763,295 | 0.00 | 0.00 | -0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 29,180 | 697,855 | +668,675 | 0.01 | 0.03 | +0.03 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 513,765 | +513,765 | 0.00 | 0.65 | +0.65 | buy |
| Bank of New York Mellon Corp | 191,261 | 671,692 | +480,431 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 24,345 | 481,949 | +457,604 | 0.01 | 0.03 | +0.02 | buy |
| VANGUARD GROUP INC | 4,410,082 | 4,788,511 | +378,429 | 0.00 | 0.00 | -0.00 | buy |
| HRT FINANCIAL LP | 0 | 374,068 | +374,068 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 0 | 296,843 | +296,843 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 271,073 | +271,073 | 0.00 | 0.00 | +0.00 | buy |
| Affinity Asset Advisors, LLC | 2,100,000 | 2,351,144 | +251,144 | 1.84 | 0.40 | -1.44 | buy |
| D. E. Shaw & Co., Inc. | 0 | 249,390 | +249,390 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 209,179 | +209,179 | 0.00 | 0.12 | +0.12 | buy |
| Virtu Financial LLC | 0 | 150,586 | +150,586 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 0 | 149,952 | +149,952 | 0.00 | 0.01 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 0 | 147,795 | +147,795 | 0.00 | 0.09 | +0.09 | buy |
| UBS Group AG | 2,695,978 | 2,816,291 | +120,313 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,847,384 | 1,954,733 | +107,349 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 0 | 93,518 | +93,518 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 91,461 | +91,461 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 52,887 | 139,394 | +86,507 | 0.00 | 0.00 | -0.00 | buy |
| Rangeley Capital, LLC | 0 | 78,200 | +78,200 | 0.00 | 0.16 | +0.16 | buy |
| Scientech Research LLC | 0 | 77,848 | +77,848 | 0.00 | 0.12 | +0.12 | buy |
| State of Alaska, Department of Revenue | 0 | 77,000 | +77,000 | 0.00 | 0.00 | +0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 72,641 | +72,641 | 0.00 | 0.08 | +0.08 | buy |
| Knott David M Jr | 275,000 | 340,000 | +65,000 | 1.08 | 0.37 | -0.71 | buy |
| SG Americas Securities, LLC | 0 | 63,622 | +63,622 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 46,413 | +46,413 | 0.00 | 0.01 | +0.01 | buy |
| Qube Research & Technologies Ltd | 0 | 45,187 | +45,187 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 98,490 | 141,883 | +43,393 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 49,136 | 89,649 | +40,513 | 0.00 | 0.00 | -0.00 | buy |
| PROFUND ADVISORS LLC | 12,334 | 51,821 | +39,487 | 0.00 | 0.00 | -0.00 | buy |
| SEI INVESTMENTS CO | 0 | 37,897 | +37,897 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 35,301 | +35,301 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 42,896 | 76,143 | +33,247 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 3,361 | 32,769 | +29,408 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 1,204 | 27,676 | +26,472 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 227,537 | 248,679 | +21,142 | 0.00 | 0.00 | -0.00 | buy |
| WINTON GROUP Ltd | 0 | 18,500 | +18,500 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 26,223 | 43,819 | +17,596 | 0.00 | 0.00 | -0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 17,515 | +17,515 | 0.00 | 0.01 | +0.01 | buy |
| Ikarian Capital, LLC | 0 | 16,479 | +16,479 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 0 | 15,271 | +15,271 | 0.00 | 0.00 | +0.00 | buy |
| PFG Investments, LLC | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 652,139 | 665,158 | +13,019 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 12,762 | +12,762 | 0.00 | 0.00 | +0.00 | buy |
| Fifth Third Wealth Advisors LLC | 0 | 12,135 | +12,135 | 0.00 | 0.00 | +0.00 | buy |
| HB Wealth Management, LLC | 0 | 11,073 | +11,073 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 10,588 | +10,588 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 10,510 | +10,510 | 0.00 | 0.00 | +0.00 | buy |
| Auxano Advisors, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,469 | 9,209 | +6,740 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 38,659 | 45,084 | +6,425 | 0.00 | 0.00 | -0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 5,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 10,790 | 14,630 | +3,840 | 0.00 | 0.00 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 41,458 | 45,088 | +3,630 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 60,794 | 63,723 | +2,929 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 13,228 | 14,757 | +1,529 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 49 | 952 | +903 | 0.00 | 0.00 | +0.00 | buy |
| MML INVESTORS SERVICES, LLC | 13,911 | 14,625 | +714 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 2,075 | 2,649 | +574 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 25 | 586 | +561 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 390 | +390 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 893 | 1,188 | +295 | 0.00 | 0.00 | -0.00 | buy |
| AMALGAMATED BANK | 2,286 | 2,537 | +251 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 6,520 | 6,553 | +33 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| SJS Investment Consulting Inc. | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 6,834 | 6,834 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 12,776 | 12,776 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 43,870 | 43,870 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MetLife Investment Management, LLC | 42,229 | 42,229 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NewEdge Advisors, LLC | 3,750 | 3,750 | 0 | 0.00 | 0.00 | -0.00 | hold |
| QUADRANT CAPITAL GROUP LLC | 248 | 248 | 0 | 0.00 | 0.00 | -0.00 | hold |
| 22NW, LP | 820,653 | 820,653 | 0 | 3.63 | 0.82 | -2.82 | hold |
| Integral Health Asset Management, LLC | 2,000,000 | 2,000,000 | 0 | 1.37 | 0.24 | -1.13 | hold |
| Velan Capital Investment Management LP | 750,000 | 750,000 | 0 | 6.62 | 1.03 | -5.59 | hold |
| Decheng Capital LLC | 59,900 | 59,900 | 0 | 0.10 | 0.02 | -0.08 | hold |
| Police & Firemen's Retirement System of New Jersey | 21,800 | 21,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 24,600 | 24,600 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EverSource Wealth Advisors, LLC | 58 | 8 | -50 | 0.00 | 0.00 | -0.00 | sell |
| FNY Investment Advisers, LLC | 100 | 0 | -100 | 0.00 | 0.00 | 0.00 | sell |
| Legal & General Group Plc | 8,216 | 8,115 | -101 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 129 | 9 | -120 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 328 | 132 | -196 | 0.00 | 0.00 | -0.00 | sell |
| J.Safra Asset Management Corp | 363 | 0 | -363 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 26,413 | 25,831 | -582 | 0.00 | 0.00 | -0.00 | sell |