| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Schonfeld Strategic Advisors LLC | 1,422,741 | 1,617,124 | +194,383 | 0.03 | 0.02 | -0.01 | buy |
| VANGUARD GROUP INC | 860,827 | 953,372 | +92,545 | 0.00 | 0.00 | -0.00 | buy |
| LPL Financial LLC | 0 | 79,502 | +79,502 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 405,694 | 440,794 | +35,100 | 0.00 | 0.00 | -0.00 | buy |
| Capital Advisors Wealth Management, LLC | 0 | 20,900 | +20,900 | 0.00 | 0.01 | +0.01 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 18,278 | +18,278 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 16,607 | +16,607 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 13,328 | +13,328 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 12,458 | +12,458 | 0.00 | 0.00 | +0.00 | buy |
| Diametric Capital, LP | 0 | 11,723 | +11,723 | 0.00 | 0.02 | +0.02 | buy |
| Caption Management, LLC | 0 | 3,500 | +3,500 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 40,835 | 44,287 | +3,452 | 0.00 | 0.00 | -0.00 | buy |
| Virtu Financial LLC | 10,142 | 13,006 | +2,864 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 135,712 | 137,567 | +1,855 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 3,231 | 4,938 | +1,707 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 13,546 | 15,158 | +1,612 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 847 | 1,910 | +1,063 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 2,151 | 3,064 | +913 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 21,560 | 21,878 | +318 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 44,908 | 45,095 | +187 | 0.00 | 0.00 | -0.00 | buy |
| Dunhill Financial, LLC | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 14 | +14 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| TSFG, LLC | 0 | 4 | +4 | 0.00 | 0.00 | 0.00 | buy |
| MAI Capital Management | 32 | 32 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 1,687 | 1,687 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,248 | 1,248 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 110,927 | 110,927 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRINCIPAL SECURITIES, INC. | 2 | 2 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 1,450,638 | 1,450,638 | 0 | 0.04 | 0.03 | -0.02 | hold |
| Plante Moran Financial Advisors, LLC | 3 | 3 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alyeska Investment Group, L.P. | 456,163 | 456,163 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 767,287 | 767,287 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Versant Venture Management, LLC | 2,007,704 | 2,007,704 | 0 | 6.55 | 5.30 | -1.25 | hold |
| NewEdge Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| 5AM Venture Management, LLC | 9,913,168 | 9,913,168 | 0 | 6.69 | 5.96 | -0.73 | hold |
| Newbridge Financial Services Group, Inc. | 18 | 18 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BRAIDWELL LP | 825,732 | 825,732 | 0 | 0.07 | 0.05 | -0.02 | hold |
| Beacon Capital Management, LLC | 8 | 8 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD Waterhouse Canada Inc. | 25 | 25 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PFS Partners, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 51 | 51 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 3,462 | 3,462 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 1,486 | 1,486 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HARBOUR INVESTMENTS, INC. | 7 | 7 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,800 | 13,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 62,363 | 62,363 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 596 | 596 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Golden State Wealth Management, LLC | 2 | 0 | -2 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 3 | 0 | -3 | 0.00 | 0.00 | 0.00 | sell |
| IFP Advisors, Inc | 3 | 0 | -3 | 0.00 | 0.00 | -0.00 | sell |
| Coppell Advisory Solutions LLC | 4 | 0 | -4 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 17 | 0 | -17 | 0.00 | 0.00 | 0.00 | sell |
| Corebridge Financial, Inc. | 9,786 | 9,642 | -144 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 492 | 292 | -200 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 510 | 0 | -510 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 15,262 | 13,985 | -1,277 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 17,505 | 14,423 | -3,082 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 374,504 | 369,914 | -4,590 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 21,653 | 11,251 | -10,402 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 11,200 | 0 | -11,200 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 326,241 | 310,013 | -16,228 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 1,220,186 | 1,201,692 | -18,494 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 71,079 | 43,491 | -27,588 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 72,000 | 42,000 | -30,000 | 0.00 | 0.00 | -0.00 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 650,758 | 620,395 | -30,363 | 0.02 | 0.01 | -0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 31,637 | 1,018 | -30,619 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 69,620 | 20,006 | -49,614 | 0.00 | 0.00 | -0.00 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 1,564,628 | 1,476,353 | -88,275 | 0.82 | 0.58 | -0.24 | sell |
| AdvisorShares Investments LLC | 88,391 | 0 | -88,391 | 0.05 | 0.00 | -0.05 | sell |
| PLATINUM INVESTMENT MANAGEMENT LTD | 434,046 | 293,320 | -140,726 | 0.07 | 0.03 | -0.05 | sell |
| Altium Capital Management LLC | 1,139,000 | 904,865 | -234,135 | 1.00 | 4.18 | +3.17 | sell |
| CITADEL ADVISORS LLC | 250,014 | 0 | -250,014 | 0.00 | 0.00 | -0.00 | sell |