| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| NEA Management Company, LLC | 281,929 | 2,922,774 | +2,640,845 | 0.05 | 0.75 | +0.70 | buy |
| ARMISTICE CAPITAL, LLC | 599,874 | 1,055,000 | +455,126 | 0.05 | 0.11 | +0.06 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 54,630 | +54,630 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 149,571 | 188,433 | +38,862 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 30,326 | 44,423 | +14,097 | 0.00 | 0.00 | +0.00 | buy |
| ABG Innovation Capital Partners III GP Ltd | 0 | 13,727 | +13,727 | 0.00 | 5.87 | +5.87 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 21,403 | 30,685 | +9,282 | 0.01 | 0.02 | +0.01 | buy |
| Tower Research Capital LLC (TRC) | 0 | 2,888 | +2,888 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 45 | 45 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ensign Peak Advisors, Inc | 2,207 | 2,207 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ikarian Capital, LLC | 20,448 | 20,448 | 0 | 0.02 | 0.02 | +0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 475 | 475 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 10,282 | 10,282 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FIDUCIARY TRUST CO | 22,353 | 22,352 | -1 | 0.00 | 0.00 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 11,012 | 0 | -11,012 | 0.00 | 0.00 | -0.00 | sell |
| WINTON GROUP Ltd | 12,401 | 0 | -12,401 | 0.00 | 0.00 | -0.00 | sell |
| Sofinnova Investments, Inc. | 38,331 | 0 | -38,331 | 0.01 | 0.00 | -0.01 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 40,548 | 0 | -40,548 | 0.00 | 0.00 | -0.00 | sell |
| Alyeska Investment Group, L.P. | 168,034 | 55,872 | -112,162 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 646,846 | 258,644 | -388,202 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 401,998 | 0 | -401,998 | 0.02 | 0.00 | -0.02 | sell |