ANNEXON INC
| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) | Type |
|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 10,050,644 | 14,549,768 | +4,499,124 | 3.72 | 5.34 | +1.62 | buy |
| MAK CAPITAL ONE LLC | 2,958,527 | 4,724,043 | +1,765,516 | 2.00 | 4.33 | +2.33 | buy |
| Palo Alto Investors LP | 2,384,192 | 2,948,090 | +563,898 | 1.67 | 2.50 | +0.83 | buy |
| Ikarian Capital, LLC | 230,244 | 580,244 | +350,000 | 0.15 | 0.46 | +0.31 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 639,902 | 912,323 | +272,421 | 0.07 | 0.11 | +0.04 | buy |
| Parkman Healthcare Partners LLC | 601,202 | 674,013 | +72,811 | 0.29 | 0.39 | +0.10 | buy |
| AXQ CAPITAL, LP | 29,108 | 58,185 | +29,077 | 0.03 | 0.04 | +0.01 | buy |
| China Universal Asset Management Co., Ltd. | 36,084 | 57,683 | +21,599 | 0.01 | 0.02 | +0.01 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 10,016 | 21,512 | +11,496 | 0.00 | 0.01 | +0.00 | buy |
| EntryPoint Capital, LLC | 42,774 | 51,421 | +8,647 | 0.08 | 0.08 | -0.00 | buy |
| ADAR1 Capital Management, LLC | 48,000 | 55,000 | +7,000 | 0.02 | 0.02 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 356,619 | 360,319 | +3,700 | 0.03 | 0.03 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 53,527 | 54,866 | +1,339 | 0.07 | 0.08 | +0.01 | buy |
| Forefront Analytics, LLC | 13,226 | 14,240 | +1,014 | 0.06 | 0.07 | +0.01 | buy |
| GF FUND MANAGEMENT CO. LTD. | 2,843 | 3,234 | +391 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 17,216 | 17,316 | +100 | 0.05 | 0.08 | +0.03 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 903,439 | 903,368 | -71 | 0.00 | 0.00 | +0.00 | sell |
| Hennion & Walsh Asset Management, Inc. | 534,986 | 509,689 | -25,297 | 0.09 | 0.10 | +0.00 | sell |
| J. Safra Sarasin Holding AG | 117,768 | 90,487 | -27,281 | 0.01 | 0.01 | -0.00 | sell |
| Bain Capital Life Sciences Investors, LLC | 5,249,069 | 5,212,674 | -36,395 | 2.02 | 2.60 | +0.59 | sell |
| Persistent Asset Partners Ltd | 93,657 | 33,625 | -60,032 | 0.23 | 0.07 | -0.15 | sell |
| Cinctive Capital Management LP | 358,986 | 268,640 | -90,346 | 0.10 | 0.10 | -0.01 | sell |
| SIRIOS CAPITAL MANAGEMENT L P | 710,256 | 575,063 | -135,193 | 0.44 | 0.39 | -0.06 | sell |
| DAFNA Capital Management LLC | 272,812 | 117,812 | -155,000 | 0.32 | 0.15 | -0.17 | sell |
| DIADEMA PARTNERS LP | 350,000 | 132,916 | -217,084 | 1.05 | 0.30 | -0.74 | sell |
| Opaleye Management Inc. | 2,600,000 | 2,331,761 | -268,239 | 1.72 | 1.70 | -0.02 | sell |
| BVF INC/IL | 9,128,080 | 8,698,173 | -429,907 | 1.54 | 1.54 | -0.01 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 683,879 | 148,941 | -534,938 | 0.01 | 0.00 | -0.01 | sell |
| TFG Asset Management GP Ltd | 2,032,455 | 1,292,455 | -740,000 | 2.15 | 1.41 | -0.74 | sell |
| J. Goldman & Co LP | 993,795 | 170,817 | -822,978 | 0.19 | 0.04 | -0.15 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,500,000 | 4,300,000 | -1,200,000 | 0.04 | 0.04 | -0.01 | sell |
| Longaeva Partners L.P. | 3,100,000 | 620,401 | -2,479,599 | 1.85 | 0.17 | -1.69 | sell |