| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 4,003,967 | 3,406,335 | -597,632 | 0.97 | 0.51 | -0.46 | sell |
| MORGAN STANLEY | 2,483,983 | 2,471,142 | -12,841 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 2,433,168 | 2,433,168 | 0 | 2.82 | 1.62 | -1.20 | hold |
| VANGUARD GROUP INC | 488,618 | 967,716 | +479,098 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 605,713 | 686,037 | +80,324 | 0.01 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 653,685 | +653,685 | 0.00 | 0.00 | +0.00 | buy |
| Nantahala Capital Management, LLC | 778,260 | 616,823 | -161,437 | 1.01 | 0.47 | -0.54 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 116,960 | 291,862 | +174,902 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 302,803 | 249,394 | -53,409 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 37,251 | 142,578 | +105,327 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 119,971 | 81,200 | -38,771 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 47,215 | 68,918 | +21,703 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 29,594 | 42,165 | +12,571 | 0.00 | 0.00 | -0.00 | buy |
| Man Group plc | 37,942 | 38,470 | +528 | 0.00 | 0.00 | -0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 37,112 | +37,112 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | 36,537 | +36,537 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 34,059 | +34,059 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 33,200 | 33,200 | 0 | 0.01 | 0.01 | -0.00 | hold |
| TWO SIGMA INVESTMENTS, LP | 0 | 33,094 | +33,094 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 32,223 | +32,223 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 58,358 | 32,045 | -26,313 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 15,412 | 24,055 | +8,643 | 0.03 | 0.02 | -0.01 | buy |
| GOLDMAN SACHS GROUP INC | 139,843 | 23,948 | -115,895 | 0.00 | 0.00 | -0.00 | sell |
| Financial Advocates Investment Management | 10,000 | 15,000 | +5,000 | 0.01 | 0.01 | -0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 14,664 | +14,664 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 14,300 | +14,300 | 0.00 | 0.00 | +0.00 | buy |
| Alpine Global Management, LLC | 0 | 12,923 | +12,923 | 0.00 | 0.02 | +0.02 | buy |
| Cubist Systematic Strategies, LLC | 50,725 | 11,519 | -39,206 | 0.01 | 0.00 | -0.01 | sell |
| Jump Financial, LLC | 25,538 | 11,431 | -14,107 | 0.01 | 0.00 | -0.01 | sell |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0 | 9,108 | +9,108 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 45,218 | 8,833 | -36,385 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 0 | 6,370 | +6,370 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 13,870 | 4,626 | -9,244 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 3,763 | 4,411 | +648 | 0.00 | 0.00 | -0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 3,541 | 3,426 | -115 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 75,688 | 2,969 | -72,719 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 0 | 1,508 | +1,508 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 1,337 | +1,337 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 989 | +989 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 472 | +472 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 370 | +370 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 166 | 166 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FEDERATED HERMES, INC. | 226 | 0 | -226 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 26,950 | 0 | -26,950 | 0.00 | 0.00 | -0.00 | sell |
| Hillsdale Investment Management Inc. | 11,750 | 0 | -11,750 | 0.01 | 0.00 | -0.01 | sell |
| Laurion Capital Management LP | 20,699 | 0 | -20,699 | 0.01 | 0.00 | -0.01 | sell |
| MACQUARIE GROUP LTD | 1,198 | 0 | -1,198 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 203,776 | 0 | -203,776 | 0.00 | 0.00 | -0.00 | sell |
| Petrus Trust Company, LTA | 23,904 | 0 | -23,904 | 0.03 | 0.00 | -0.03 | sell |
| HRT FINANCIAL LP | 31,921 | 0 | -31,921 | 0.00 | 0.00 | -0.00 | sell |
| Informed Momentum Co LLC | 75,625 | 0 | -75,625 | 0.16 | 0.00 | -0.16 | sell |
| Brevan Howard Capital Management LP | 15,034 | 0 | -15,034 | 0.02 | 0.00 | -0.02 | sell |
| Marathon Trading Investment Management LLC | 28,000 | 0 | -28,000 | 0.15 | 0.00 | -0.15 | sell |
| JANE STREET GROUP, LLC | 72,013 | 0 | -72,013 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 13,316 | 0 | -13,316 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 14,426 | 0 | -14,426 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 10,379 | 0 | -10,379 | 0.04 | 0.00 | -0.04 | sell |
| ExodusPoint Capital Management, LP | 19,431 | 0 | -19,431 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 19,698 | 0 | -19,698 | 0.00 | 0.00 | -0.00 | sell |
| Y-Intercept (Hong Kong) Ltd | 10,491 | 0 | -10,491 | 0.01 | 0.00 | -0.01 | sell |
| BOSUN ASSET MANAGEMENT, LLC | 18,499 | 0 | -18,499 | 0.14 | 0.00 | -0.14 | sell |
| JPMORGAN CHASE & CO | 32,115 | 0 | -32,115 | 0.00 | 0.00 | -0.00 | sell |
| EntryPoint Capital, LLC | 1,632 | 0 | -1,632 | 0.02 | 0.00 | -0.02 | sell |
| Jefferies Financial Group Inc. | 10,900 | 0 | -10,900 | 0.00 | 0.00 | -0.00 | sell |