| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 0 | 900,000 | +900,000 | 0.00 | 0.60 | +0.60 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 520,000 | +520,000 | 0.00 | 0.15 | +0.15 | buy |
| RWA WEALTH PARTNERS, LLC | 0 | 312,779 | +312,779 | 0.00 | 0.03 | +0.03 | buy |
| Affinity Asset Advisors, LLC | 550,765 | 657,154 | +106,389 | 0.64 | 0.82 | +0.18 | buy |
| Allostery Investments LP | 73,314 | 107,141 | +33,827 | 1.07 | 1.24 | +0.17 | buy |
| ADAR1 Capital Management, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.02 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 104,853 | 107,812 | +2,959 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 109,972 | 111,972 | +2,000 | 0.71 | 0.92 | +0.22 | buy |
| VANGUARD GROUP INC | 165,801 | 166,941 | +1,140 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 19,477 | 20,223 | +746 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 133,235 | 133,726 | +491 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 98,519 | 98,951 | +432 | 0.00 | 0.00 | +0.00 | buy |
| Avion Wealth | 0 | 5 | +5 | 0.00 | 0.00 | 0.00 | buy |
| ORBIMED ADVISORS LLC | 967,000 | 967,000 | 0 | 0.15 | 0.19 | +0.04 | hold |
| BVF INC/IL | 1,036,679 | 1,036,679 | 0 | 0.26 | 0.34 | +0.08 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 4 | 4 | 0 | 0.00 | 0.00 | +0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 967,000 | 967,000 | 0 | 0.10 | 0.13 | +0.03 | hold |
| Sio Capital Management, LLC | 71,458 | 71,458 | 0 | 0.15 | 0.17 | +0.02 | hold |
| Parallel Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Key FInancial Inc | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Commodore Capital LP | 483,000 | 483,000 | 0 | 0.26 | 0.29 | +0.02 | hold |
| TCG Crossover Management, LLC | 483,000 | 483,000 | 0 | 0.35 | 0.53 | +0.18 | hold |
| SBI Securities Co., Ltd. | 22 | 22 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Activest Wealth Management | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHERN TRUST CORP | 22,673 | 22,673 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| GROUP ONE TRADING LLC | 2 | 2 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Tower Research Capital LLC (TRC) | 4,130 | 0 | -4,130 | 0.00 | 0.00 | -0.00 | sell |
| Deep Track Capital, LP | 867,000 | 859,876 | -7,124 | 0.24 | 0.22 | -0.02 | sell |
| MARSHALL WACE, LLP | 15,323 | 0 | -15,323 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 40,000 | 10,289 | -29,711 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 60,000 | 0 | -60,000 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 117,356 | 0 | -117,356 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 163,992 | 0 | -163,992 | 0.04 | 0.00 | -0.04 | sell |
| Ikarian Capital, LLC | 970,259 | 200,000 | -770,259 | 2.06 | 0.52 | -1.54 | sell |