| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 0 | 967,000 | +967,000 | 0.00 | 0.17 | +0.17 | buy |
| BVF INC/IL | 0 | 967,000 | +967,000 | 0.00 | 0.27 | +0.27 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 0 | 967,000 | +967,000 | 0.00 | 0.11 | +0.11 | buy |
| Deep Track Capital, LP | 0 | 967,000 | +967,000 | 0.00 | 0.29 | +0.29 | buy |
| Ikarian Capital, LLC | 54,730 | 970,359 | +915,629 | 0.21 | 2.86 | +2.65 | buy |
| TCG Crossover Management, LLC | 0 | 483,000 | +483,000 | 0.00 | 0.39 | +0.39 | buy |
| Commodore Capital LP | 40,000 | 483,000 | +443,000 | 0.03 | 0.29 | +0.25 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 164,092 | +164,092 | 0.00 | 0.05 | +0.05 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 10,111 | +10,111 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 376 | +376 | 0.00 | 0.00 | +0.00 | buy |
| Avion Wealth | 0 | 5 | +5 | 0.00 | 0.00 | 0.00 | buy |
| Jaffetilchin Investment Partners, LLC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 10,368 | 10,368 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 4 | 4 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sio Capital Management, LLC | 71,458 | 71,458 | 0 | 0.34 | 0.30 | -0.03 | hold |
| Parallel Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Affinity Asset Advisors, LLC | 45,000 | 45,000 | 0 | 0.09 | 0.07 | -0.02 | hold |
| Logos Global Management LP | 539,079 | 539,079 | 0 | 0.77 | 0.57 | -0.20 | hold |
| Key FInancial Inc | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Activest Wealth Management | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| GROUP ONE TRADING LLC | 2 | 2 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Banque Cantonale Vaudoise | 338 | 0 | -338 | 0.00 | 0.00 | -0.00 | sell |