| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,000,000 | 1,000,000 | 0 | 0.07 | 0.07 | -0.01 | hold |
| Soleus Capital Management, L.P. | 783,904 | 783,904 | 0 | 0.29 | 0.27 | -0.01 | hold |
| Aisling Capital Management LP | 521,114 | 521,114 | 0 | 0.73 | 0.89 | +0.16 | hold |
| VANGUARD GROUP INC | 13,359 | 252,801 | +239,442 | 0.00 | 0.00 | +0.00 | buy |
| BML Capital Management, LLC | 160,424 | 160,424 | 0 | 0.45 | 0.47 | +0.02 | hold |
| MILLENNIUM MANAGEMENT LLC | 66,134 | 61,587 | -4,547 | 0.00 | 0.00 | -0.00 | sell |
| MERITAGE PORTFOLIO MANAGEMENT | 46,000 | 46,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 44,686 | 44,028 | -658 | 0.00 | 0.00 | -0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 22,256 | +22,256 | 0.00 | 0.00 | +0.00 | buy |
| J. Goldman & Co LP | 0 | 18,900 | +18,900 | 0.00 | 0.00 | +0.00 | buy |
| TRITONPOINT WEALTH, LLC | 0 | 15,119 | +15,119 | 0.00 | 0.01 | +0.01 | buy |
| FIRST MANHATTAN CO. LLC. | 13,226 | 13,226 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Atria Investments, Inc | 0 | 11,207 | +11,207 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,181 | 921 | -1,260 | 0.00 | 0.00 | -0.00 | sell |
| BROWN BROTHERS HARRIMAN & CO | 0 | 308 | +308 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 1,229 | 1 | -1,228 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 297,380 | 0 | -297,380 | 0.02 | 0.00 | -0.02 | sell |
| Stonepine Capital Management, LLC | 522,602 | 0 | -522,602 | 1.72 | 0.00 | -1.72 | sell |
| Alyeska Investment Group, L.P. | 75,082 | 0 | -75,082 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 781 | 0 | -781 | 0.00 | 0.00 | -0.00 | sell |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |