| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,300,000 | 1,300,000 | 0 | 0.05 | 0.04 | -0.01 | hold |
| Soleus Capital Management, L.P. | 783,904 | 783,904 | 0 | 0.12 | 0.09 | -0.03 | hold |
| Aisling Capital Management LP | 521,114 | 521,114 | 0 | 0.35 | 0.23 | -0.11 | hold |
| VANGUARD GROUP INC | 339,148 | 339,148 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 96,382 | 97,032 | +650 | 0.00 | 0.00 | -0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 59,047 | 93,433 | +34,386 | 0.00 | 0.00 | +0.00 | buy |
| WEALTHEDGE INVESTMENT ADVISORS, LLC | 108,291 | 87,468 | -20,823 | 0.09 | 0.06 | -0.03 | sell |
| Stonepine Capital Management, LLC | 367,371 | 85,000 | -282,371 | 0.60 | 0.13 | -0.46 | sell |
| MILLENNIUM MANAGEMENT LLC | 59,388 | 52,870 | -6,518 | 0.00 | 0.00 | -0.00 | sell |
| 180 WEALTH ADVISORS, LLC | 16,400 | 50,450 | +34,050 | 0.00 | 0.01 | +0.01 | buy |
| MERITAGE PORTFOLIO MANAGEMENT | 46,000 | 46,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Atria Investments, Inc | 37,264 | 44,700 | +7,436 | 0.00 | 0.00 | -0.00 | buy |
| Corient Private Wealth LLC | 38,000 | 38,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cetera Investment Advisers | 27,340 | 36,385 | +9,045 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 35,416 | 36,000 | +584 | 0.00 | 0.00 | -0.00 | buy |
| Sound View Wealth Advisors Group, LLC | 0 | 20,100 | +20,100 | 0.00 | 0.00 | +0.00 | buy |
| J. Goldman & Co LP | 18,900 | 18,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TRITONPOINT WEALTH, LLC | 15,119 | 15,119 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Weaver Consulting Group | 0 | 13,393 | +13,393 | 0.00 | 0.01 | +0.01 | buy |
| FIRST MANHATTAN CO. LLC. | 13,226 | 13,226 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Tower Research Capital LLC (TRC) | 2,982 | 2,993 | +11 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 0 | 536 | +536 | 0.00 | 0.00 | +0.00 | buy |
| BROWN BROTHERS HARRIMAN & CO | 308 | 308 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 121 | 121 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 19 | +19 | 0.00 | 0.00 | +0.00 | buy |
| Cambridge Investment Research Advisors, Inc. | 23,539 | 0 | -23,539 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 15,407 | 0 | -15,407 | 0.00 | 0.00 | -0.00 | sell |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| PVG ASSET MANAGEMENT CORP | 30,385 | 0 | -30,385 | 0.25 | 0.00 | -0.25 | sell |