| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,300,000 | 1,300,000 | 0 | 0.04 | 0.06 | +0.02 | hold |
| Soleus Capital Management, L.P. | 783,904 | 683,904 | -100,000 | 0.09 | 0.11 | +0.03 | sell |
| Aisling Capital Management LP | 521,114 | 521,114 | 0 | 0.23 | 0.35 | +0.12 | hold |
| VANGUARD GROUP INC | 339,148 | 376,624 | +37,476 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 97,032 | 98,852 | +1,820 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 93,433 | 76,705 | -16,728 | 0.00 | 0.00 | +0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 36,000 | 70,000 | +34,000 | 0.00 | 0.00 | +0.00 | buy |
| MERITAGE PORTFOLIO MANAGEMENT | 46,000 | 61,539 | +15,539 | 0.00 | 0.01 | +0.01 | buy |
| Stonehage Fleming Financial Services Holdings Ltd | 0 | 53,703 | +53,703 | 0.00 | 0.00 | +0.00 | buy |
| 180 WEALTH ADVISORS, LLC | 50,450 | 42,700 | -7,750 | 0.01 | 0.02 | +0.00 | sell |
| Atria Investments, Inc | 44,700 | 38,086 | -6,614 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 52,870 | 34,388 | -18,482 | 0.00 | 0.00 | +0.00 | sell |
| Cetera Investment Advisers | 36,385 | 25,365 | -11,020 | 0.00 | 0.00 | -0.00 | sell |
| Summit Financial, LLC | 0 | 25,092 | +25,092 | 0.00 | 0.00 | +0.00 | buy |
| Sound View Wealth Advisors Group, LLC | 20,100 | 20,100 | 0 | 0.00 | 0.00 | +0.00 | hold |
| J. Goldman & Co LP | 18,900 | 18,900 | 0 | 0.00 | 0.00 | +0.00 | hold |
| XTX Topco Ltd | 0 | 15,345 | +15,345 | 0.00 | 0.00 | +0.00 | buy |
| TRITONPOINT WEALTH, LLC | 15,119 | 15,119 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FIRST MANHATTAN CO. LLC. | 13,226 | 13,226 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rockefeller Capital Management L.P. | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 4,927 | +4,927 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,993 | 666 | -2,327 | 0.00 | 0.00 | -0.00 | sell |
| BROWN BROTHERS HARRIMAN & CO | 308 | 308 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SBI Securities Co., Ltd. | 121 | 122 | +1 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 57 | +57 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 19 | 19 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Stonepine Capital Management, LLC | 85,000 | 0 | -85,000 | 0.13 | 0.00 | -0.13 | sell |
| Weaver Consulting Group | 13,393 | 0 | -13,393 | 0.01 | 0.00 | -0.01 | sell |
| Corient Private Wealth LLC | 38,000 | 0 | -38,000 | 0.00 | 0.00 | -0.00 | sell |
| Federation des caisses Desjardins du Quebec | 200 | 0 | -200 | 0.00 | 0.00 | -0.00 | sell |
| WEALTHEDGE INVESTMENT ADVISORS, LLC | 87,468 | 0 | -87,468 | 0.06 | 0.00 | -0.06 | sell |
| FMR LLC | 536 | 0 | -536 | 0.00 | 0.00 | -0.00 | sell |