| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 2,024,221 | 3,032,808 | +1,008,587 | 0.23 | 0.24 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 207,778 | 538,868 | +331,090 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 75,092 | 390,614 | +315,522 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 896,163 | 1,106,703 | +210,540 | 0.00 | 0.00 | -0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 109,157 | +109,157 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 156,037 | 249,102 | +93,065 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 75,267 | 150,708 | +75,441 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 12,000 | 77,113 | +65,113 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 412,687 | 477,204 | +64,517 | 0.01 | 0.01 | -0.00 | buy |
| Ballentine Partners, LLC | 0 | 49,664 | +49,664 | 0.00 | 0.01 | +0.01 | buy |
| Twelve Points Wealth Management LLC | 0 | 43,388 | +43,388 | 0.00 | 0.09 | +0.09 | buy |
| RHUMBLINE ADVISERS | 0 | 32,166 | +32,166 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Wealth | 0 | 28,656 | +28,656 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 27,683 | +27,683 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 27,400 | +27,400 | 0.00 | 0.00 | +0.00 | buy |
| Alpine Global Management, LLC | 0 | 26,105 | +26,105 | 0.00 | 0.03 | +0.03 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 20,867 | +20,867 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 30,000 | 47,500 | +17,500 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 17,500 | +17,500 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 33,010 | 49,303 | +16,293 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 0 | 15,876 | +15,876 | 0.00 | 0.00 | +0.00 | buy |
| SANDERS MORRIS HARRIS LLC | 19,100 | 34,800 | +15,700 | 0.03 | 0.03 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 11,427 | +11,427 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 0 | 10,232 | +10,232 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 9,357 | +9,357 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 8,837 | +8,837 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 7,532 | +7,532 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 20,657 | 24,352 | +3,695 | 0.00 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 0 | 3,069 | +3,069 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 22,791 | 25,682 | +2,891 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 2,704 | +2,704 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 0 | 2,554 | +2,554 | 0.00 | 0.01 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 2,000 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 0 | 1,015 | +1,015 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 955 | +955 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 44,512 | 45,431 | +919 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 730 | +730 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 181 | 231 | +50 | 0.00 | 0.00 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 86,105 | 86,105 | 0 | 0.02 | 0.01 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 5,434,399 | 5,434,399 | 0 | 0.62 | 0.41 | -0.21 | hold |
| CWM, LLC | 40,524 | 40,524 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Perigon Wealth Management, LLC | 85,185 | 85,185 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Vivo Capital, LLC | 1,650,440 | 1,650,440 | 0 | 1.18 | 0.90 | -0.28 | hold |
| Requisite Capital Management, LLC | 55,648 | 55,648 | 0 | 0.11 | 0.07 | -0.04 | hold |
| MACQUARIE GROUP LTD | 882 | 0 | -882 | 0.00 | 0.00 | -0.00 | sell |
| HighTower Advisors, LLC | 43,234 | 42,234 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 3,608 | 0 | -3,608 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 19,959 | 15,232 | -4,727 | 0.00 | 0.00 | -0.00 | sell |
| Marquette Asset Management, LLC | 12,381 | 0 | -12,381 | 0.02 | 0.00 | -0.02 | sell |
| CITIGROUP INC | 19,536 | 6,005 | -13,531 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 14,119 | 0 | -14,119 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 40,214 | 23,922 | -16,292 | 0.00 | 0.00 | -0.00 | sell |
| Ensign Peak Advisors, Inc | 120,000 | 102,156 | -17,844 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 19,528 | 0 | -19,528 | 0.00 | 0.00 | -0.00 | sell |
| Brevan Howard Capital Management LP | 21,479 | 0 | -21,479 | 0.02 | 0.00 | -0.02 | sell |
| Y-Intercept (Hong Kong) Ltd | 22,259 | 0 | -22,259 | 0.02 | 0.00 | -0.02 | sell |
| Man Group plc | 81,541 | 30,731 | -50,810 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 58,123 | 0 | -58,123 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 58,794 | 0 | -58,794 | 0.00 | 0.00 | -0.00 | sell |
| AWM Investment Company, Inc. | 584,664 | 521,314 | -63,350 | 0.70 | 0.42 | -0.28 | sell |
| Acuitas Investments, LLC | 66,044 | 0 | -66,044 | 0.30 | 0.00 | -0.30 | sell |
| Qube Research & Technologies Ltd | 67,946 | 0 | -67,946 | 0.00 | 0.00 | -0.00 | sell |
| Resolute Capital Asset Partners LLC | 175,000 | 80,000 | -95,000 | 0.83 | 0.27 | -0.56 | sell |
| Informed Momentum Co LLC | 97,079 | 0 | -97,079 | 0.14 | 0.00 | -0.14 | sell |
| GOLDMAN SACHS GROUP INC | 147,382 | 43,858 | -103,524 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 124,951 | 0 | -124,951 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 156,107 | 0 | -156,107 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 289,456 | 64,906 | -224,550 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 621,834 | 13,320 | -608,514 | 0.00 | 0.00 | -0.00 | sell |