| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 0 | 561,751 | +561,751 | 0.00 | 0.00 | +0.00 | buy |
| Stonepine Capital Management, LLC | 30,000 | 456,439 | +426,439 | 0.14 | 2.43 | +2.29 | buy |
| Boxer Capital Management, LLC | 0 | 205,000 | +205,000 | 0.00 | 0.13 | +0.13 | buy |
| XTX Topco Ltd | 0 | 35,352 | +35,352 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 31,531 | +31,531 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 14,032 | +14,032 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 77,054 | 80,879 | +3,825 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 2,595 | +2,595 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 1,122 | +1,122 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 507 | 1,230 | +723 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 3,502 | 3,505 | +3 | 0.00 | 0.00 | +0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 563,239 | 563,239 | 0 | 0.06 | 0.07 | +0.01 | hold |
| Banque Cantonale Vaudoise | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Velan Capital Investment Management LP | 827,500 | 827,500 | 0 | 2.71 | 4.12 | +1.41 | hold |
| TD Waterhouse Canada Inc. | 142 | 142 | 0 | 0.00 | 0.00 | +0.00 | hold |
| LRI Investments, LLC | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHERN TRUST CORP | 14,994 | 14,994 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE STREET CORP | 37,979 | 37,979 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Dogwood Wealth Management LLC | 1 | 0 | -1 | 0.00 | 0.00 | -0.00 | sell |
| Global Retirement Partners, LLC | 86 | 0 | -86 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 27,709 | 27,495 | -214 | 0.00 | 0.00 | +0.00 | sell |
| CITIGROUP INC | 487 | 0 | -487 | 0.00 | 0.00 | -0.00 | sell |
| SCOTIA CAPITAL INC. | 15,843 | 14,393 | -1,450 | 0.00 | 0.00 | +0.00 | sell |
| Rubric Capital Management LP | 687,500 | 669,500 | -18,000 | 0.04 | 0.05 | +0.01 | sell |
| Schonfeld Strategic Advisors LLC | 19,650 | 0 | -19,650 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 26,275 | 0 | -26,275 | 0.01 | 0.00 | -0.01 | sell |
| Scientech Research LLC | 30,534 | 0 | -30,534 | 0.13 | 0.00 | -0.13 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 35,003 | 0 | -35,003 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 115,721 | 72,465 | -43,256 | 0.00 | 0.00 | -0.00 | sell |