| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Vestal Point Capital, LP | 4,690,000 | 6,500,000 | +1,810,000 | 3.26 | 2.82 | -0.45 | buy |
| STATE STREET CORP | 3,559,501 | 5,141,195 | +1,581,694 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 4,234,158 | 5,541,271 | +1,307,113 | 0.00 | 0.00 | +0.00 | buy |
| Capital World Investors | 0 | 893,327 | +893,327 | 0.00 | 0.00 | +0.00 | buy |
| Longaeva Partners L.P. | 927,729 | 1,490,202 | +562,473 | 2.09 | 1.11 | -0.98 | buy |
| UBS Group AG | 423,425 | 976,362 | +552,937 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 25,989 | 485,212 | +459,223 | 0.00 | 0.01 | +0.01 | buy |
| Integral Health Asset Management, LLC | 300,000 | 700,000 | +400,000 | 0.29 | 0.57 | +0.29 | buy |
| Fisher Asset Management, LLC | 0 | 384,831 | +384,831 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 179,759 | 546,297 | +366,538 | 0.00 | 0.01 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 353,733 | +353,733 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 430,986 | 780,696 | +349,710 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 344,203 | +344,203 | 0.00 | 0.00 | +0.00 | buy |
| STEMPOINT CAPITAL LP | 0 | 315,226 | +315,226 | 0.00 | 0.94 | +0.94 | buy |
| CITIGROUP INC | 171,102 | 477,410 | +306,308 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 261,204 | 561,250 | +300,046 | 0.10 | 0.18 | +0.08 | buy |
| Foresite Capital Management V, LLC | 0 | 265,000 | +265,000 | 0.00 | 1.52 | +1.52 | buy |
| GOLDMAN SACHS GROUP INC | 1,077,573 | 1,318,659 | +241,086 | 0.00 | 0.00 | -0.00 | buy |
| HighVista Strategies LLC | 0 | 226,546 | +226,546 | 0.00 | 0.97 | +0.97 | buy |
| Squarepoint Ops LLC | 0 | 224,535 | +224,535 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 1,152,930 | 1,343,700 | +190,770 | 0.01 | 0.01 | -0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 3,555,877 | 3,710,877 | +155,000 | 1.24 | 1.14 | -0.10 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,384,998 | 2,520,229 | +135,231 | 0.00 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 77,359 | 209,694 | +132,335 | 0.01 | 0.02 | +0.01 | buy |
| ARK Investment Management LLC | 1,602,539 | 1,721,135 | +118,596 | 0.20 | 0.21 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 118,000 | +118,000 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 132,094 | 223,363 | +91,269 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 736,558 | 802,153 | +65,595 | 0.00 | 0.00 | -0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 62,503 | +62,503 | 0.00 | 0.01 | +0.01 | buy |
| Rafferty Asset Management, LLC | 90,515 | 149,523 | +59,008 | 0.01 | 0.01 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 55,138 | +55,138 | 0.00 | 0.02 | +0.02 | buy |
| MORGAN STANLEY | 4,881,069 | 4,931,999 | +50,930 | 0.01 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 8,875,194 | 8,925,642 | +50,448 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 805,682 | 854,466 | +48,784 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 275,178 | 321,360 | +46,182 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 35,976 | 82,108 | +46,132 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | 44,976 | +44,976 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 44,200 | +44,200 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,248,361 | 3,290,233 | +41,872 | 0.01 | 0.01 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 20,520 | 61,774 | +41,254 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 42,878 | 78,057 | +35,179 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 34,580 | 66,993 | +32,413 | 0.02 | 0.04 | +0.02 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 68,019 | 99,042 | +31,023 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 50,553 | 81,455 | +30,902 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 29,537 | +29,537 | 0.00 | 0.06 | +0.06 | buy |
| XTX Topco Ltd | 11,520 | 40,386 | +28,866 | 0.01 | 0.01 | +0.01 | buy |
| Nuveen, LLC | 784,409 | 812,601 | +28,192 | 0.00 | 0.00 | -0.00 | buy |
| State of New Jersey Common Pension Fund D | 0 | 25,983 | +25,983 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 86,423 | 107,663 | +21,240 | 0.03 | 0.02 | -0.00 | buy |
| Headlands Technologies LLC | 0 | 20,145 | +20,145 | 0.00 | 0.04 | +0.04 | buy |
| E Fund Management Co., Ltd. | 0 | 18,796 | +18,796 | 0.00 | 0.01 | +0.01 | buy |
| Russell Investments Group, Ltd. | 63,482 | 81,841 | +18,359 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 16,406 | +16,406 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 65,545 | 81,760 | +16,215 | 0.09 | 0.10 | +0.01 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 14,489 | +14,489 | 0.00 | 0.04 | +0.04 | buy |
| Allspring Global Investments Holdings, LLC | 0 | 13,410 | +13,410 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 13,328 | +13,328 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 13,256 | +13,256 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 11,553 | +11,553 | 0.00 | 0.02 | +0.02 | buy |
| Tower Research Capital LLC (TRC) | 4,511 | 15,400 | +10,889 | 0.00 | 0.01 | +0.00 | buy |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 80,000 | 90,000 | +10,000 | 0.02 | 0.02 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 31,191 | 40,928 | +9,737 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 80,037 | 89,518 | +9,481 | 0.02 | 0.02 | +0.00 | buy |
| Bank of New York Mellon Corp | 288,143 | 295,345 | +7,202 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 172,364 | 179,177 | +6,813 | 0.00 | 0.00 | -0.00 | buy |
| Brevan Howard Capital Management LP | 20,680 | 26,501 | +5,821 | 0.01 | 0.00 | -0.00 | buy |
| Quantinno Capital Management LP | 16,767 | 22,133 | +5,366 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 118,598 | 123,367 | +4,769 | 0.00 | 0.00 | -0.00 | buy |
| Rockefeller Capital Management L.P. | 1,068 | 5,318 | +4,250 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 47,288 | 50,357 | +3,069 | 0.00 | 0.00 | -0.00 | buy |
| KBC Group NV | 0 | 2,192 | +2,192 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 726 | 2,556 | +1,830 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 16,518 | 18,250 | +1,732 | 0.02 | 0.02 | -0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 0 | 1,535 | +1,535 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 1,456 | +1,456 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 18,104 | 19,121 | +1,017 | 0.00 | 0.00 | -0.00 | buy |
| Federation des caisses Desjardins du Quebec | 1,590 | 2,590 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 33,515 | 34,421 | +906 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 0 | 841 | +841 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT SECURITIES GROUP LLC | 0 | 779 | +779 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 55,345 | 55,948 | +603 | 0.01 | 0.00 | -0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 4,926 | 5,364 | +438 | 0.00 | 0.00 | -0.00 | buy |
| Virtus Investment Advisers, LLC | 13,949 | 14,299 | +350 | 0.07 | 0.06 | -0.01 | buy |
| Smartleaf Asset Management LLC | 828 | 1,132 | +304 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 66 | 344 | +278 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,992 | 2,266 | +274 | 0.00 | 0.00 | -0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 4 | 275 | +271 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH THIRD BANCORP | 0 | 248 | +248 | 0.00 | 0.00 | +0.00 | buy |
| Accent Capital Management, LLC | 380 | 568 | +188 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 501 | 576 | +75 | 0.00 | 0.00 | -0.00 | buy |
| Allworth Financial LP | 94 | 145 | +51 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 202 | 249 | +47 | 0.00 | 0.00 | +0.00 | buy |
| Fortitude Family Office, LLC | 0 | 31 | +31 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 49 | 69 | +20 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 343 | 359 | +16 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| Hughes Financial Services, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| TWIN PEAKS WEALTH ADVISORS, LLC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 27,150 | 27,150 | 0 | 0.00 | 0.00 | -0.00 | hold |