| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 218,453 | 3,703,594 | +3,485,141 | 0.01 | 0.10 | +0.09 | buy |
| UBS Group AG | 673,147 | 1,589,040 | +915,893 | 0.00 | 0.00 | +0.00 | buy |
| Vestal Point Capital, LP | 1,125,552 | 2,000,000 | +874,448 | 0.95 | 1.20 | +0.24 | buy |
| PERCEPTIVE ADVISORS LLC | 297,553 | 1,096,985 | +799,432 | 0.13 | 0.47 | +0.34 | buy |
| MORGAN STANLEY | 1,466,860 | 2,167,121 | +700,261 | 0.00 | 0.00 | +0.00 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 755,970 | 1,391,638 | +635,668 | 0.01 | 0.01 | +0.00 | buy |
| Nikko Asset Management Americas, Inc. | 755,970 | 1,389,274 | +633,304 | 0.12 | 0.16 | +0.04 | buy |
| Deep Track Capital, LP | 5,500,000 | 6,064,910 | +564,910 | 2.12 | 2.22 | +0.11 | buy |
| Kynam Capital Management, LP | 800,000 | 1,173,605 | +373,605 | 0.81 | 1.44 | +0.63 | buy |
| Handelsbanken Fonder AB | 0 | 280,000 | +280,000 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 1,317,458 | 1,589,035 | +271,577 | 0.02 | 0.02 | +0.00 | buy |
| Pictet Asset Management Holding SA | 1,754,280 | 1,998,634 | +244,354 | 0.02 | 0.02 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 179,120 | 374,850 | +195,730 | 0.01 | 0.02 | +0.01 | buy |
| ExodusPoint Capital Management, LP | 19,168 | 193,494 | +174,326 | 0.00 | 0.03 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,724,368 | 1,881,960 | +157,592 | 0.00 | 0.00 | -0.00 | buy |
| Affinity Asset Advisors, LLC | 810,669 | 967,620 | +156,951 | 1.51 | 1.63 | +0.12 | buy |
| Polar Asset Management Partners Inc. | 0 | 154,400 | +154,400 | 0.00 | 0.04 | +0.04 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2,913,368 | 3,033,844 | +120,476 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 114,499 | +114,499 | 0.00 | 0.03 | +0.03 | buy |
| FMR LLC | 10,332,211 | 10,442,467 | +110,256 | 0.01 | 0.01 | -0.00 | buy |
| BARCLAYS PLC | 144,775 | 254,870 | +110,095 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 0 | 110,000 | +110,000 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 6,815 | 113,233 | +106,418 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 195,400 | 284,600 | +89,200 | 0.01 | 0.01 | +0.00 | buy |
| Cinctive Capital Management LP | 38,770 | 116,133 | +77,363 | 0.04 | 0.07 | +0.04 | buy |
| GOLDMAN SACHS GROUP INC | 507,471 | 584,519 | +77,048 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 159,530 | 232,055 | +72,525 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 62,871 | +62,871 | 0.00 | 0.01 | +0.01 | buy |
| Qube Research & Technologies Ltd | 294,747 | 356,742 | +61,995 | 0.01 | 0.01 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 10,550 | 70,670 | +60,120 | 0.05 | 0.02 | -0.04 | buy |
| MILLENNIUM MANAGEMENT LLC | 874,399 | 927,558 | +53,159 | 0.01 | 0.01 | -0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 205,100 | 257,816 | +52,716 | 0.06 | 0.07 | +0.01 | buy |
| Trexquant Investment LP | 0 | 51,533 | +51,533 | 0.00 | 0.01 | +0.01 | buy |
| VANGUARD GROUP INC | 4,415,122 | 4,465,507 | +50,385 | 0.00 | 0.00 | -0.00 | buy |
| T. Rowe Price Investment Management, Inc. | 2,428,283 | 2,473,956 | +45,673 | 0.02 | 0.02 | -0.00 | buy |
| AlphaQuest LLC | 2,572 | 46,265 | +43,693 | 0.00 | 0.05 | +0.05 | buy |
| Verition Fund Management LLC | 0 | 41,922 | +41,922 | 0.00 | 0.00 | +0.00 | buy |
| Integral Health Asset Management, LLC | 275,000 | 310,000 | +35,000 | 0.36 | 0.33 | -0.03 | buy |
| Mach-1 Financial Group, LLC | 0 | 32,087 | +32,087 | 0.00 | 0.11 | +0.11 | buy |
| Man Group plc | 0 | 28,303 | +28,303 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 582,066 | 607,127 | +25,061 | 0.00 | 0.00 | -0.00 | buy |
| NEOS Investment Management LLC | 59,146 | 81,112 | +21,966 | 0.01 | 0.01 | -0.00 | buy |
| TEMA ETFS LLC | 59,146 | 81,112 | +21,966 | 0.21 | 0.25 | +0.04 | buy |
| Invesco Ltd. | 117,635 | 137,271 | +19,636 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 205,078 | 224,125 | +19,047 | 0.00 | 0.00 | -0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 18,902 | +18,902 | 0.00 | 0.04 | +0.04 | buy |
| Creative Planning | 0 | 16,409 | +16,409 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 110,488 | 125,227 | +14,739 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 116,700 | 131,000 | +14,300 | 0.00 | 0.00 | -0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 14,249 | 26,406 | +12,157 | 0.02 | 0.03 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 30,686 | 42,186 | +11,500 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 0 | 10,000 | +10,000 | 0.00 | 0.11 | +0.11 | buy |
| ADAR1 Capital Management, LLC | 21,200 | 31,200 | +10,000 | 0.05 | 0.06 | +0.01 | buy |
| FRANKLIN RESOURCES INC | 61,509 | 70,861 | +9,352 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 42,830 | 52,131 | +9,301 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 926 | 7,041 | +6,115 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 31,567 | 37,214 | +5,647 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 45,690 | 50,482 | +4,792 | 0.00 | 0.00 | -0.00 | buy |
| KLP KAPITALFORVALTNING AS | 11,100 | 15,400 | +4,300 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 58,619 | 62,420 | +3,801 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,938 | 6,413 | +3,475 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 16,095 | 19,503 | +3,408 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 42,105 | 45,218 | +3,113 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 2,916 | +2,916 | 0.00 | 0.00 | +0.00 | buy |
| Arizona State Retirement System | 17,253 | 20,004 | +2,751 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 15,582 | 18,104 | +2,522 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 16,156 | 18,404 | +2,248 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 454 | 2,035 | +1,581 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 19,423 | 20,714 | +1,291 | 0.00 | 0.00 | -0.00 | buy |
| Point72 Hong Kong Ltd | 0 | 992 | +992 | 0.00 | 0.00 | +0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 43,006 | 43,544 | +538 | 0.00 | 0.00 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 29,660 | 30,170 | +510 | 0.00 | 0.00 | -0.00 | buy |
| Caitong International Asset Management Co., Ltd | 37 | 519 | +482 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 2,539 | 2,945 | +406 | 0.00 | 0.00 | -0.00 | buy |
| Accent Capital Management, LLC | 0 | 250 | +250 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 129 | +129 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 100 | +100 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 599 | 695 | +96 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 15,222 | 15,312 | +90 | 0.02 | 0.02 | -0.00 | buy |
| Woodline Partners LP | 100,204 | 100,271 | +67 | 0.01 | 0.01 | -0.00 | buy |
| J.Safra Asset Management Corp | 97 | 158 | +61 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 160 | 195 | +35 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 0 | 27 | +27 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 5 | 9 | +4 | 0.00 | 0.00 | 0.00 | buy |
| TWIN PEAKS WEALTH ADVISORS, LLC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 4,636 | 4,636 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BESSEMER GROUP INC | 306,003 | 306,003 | 0 | 0.01 | 0.01 | -0.00 | hold |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Ameritas Investment Partners, Inc. | 7,345 | 7,345 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD ASSET MANAGEMENT INC | 42,420 | 42,420 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 66,994 | 66,994 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 63,320 | 63,320 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 3,882,125 | 3,882,125 | 0 | 0.51 | 0.43 | -0.08 | hold |
| JANUS HENDERSON GROUP PLC | 26,200 | 26,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BBR PARTNERS, LLC | 20,988 | 20,988 | 0 | 0.02 | 0.01 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,829 | 18,829 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Jasper Ridge Partners, L.P. | 95,711 | 95,711 | 0 | 0.04 | 0.03 | -0.01 | hold |
| Ensign Peak Advisors, Inc | 230,828 | 230,828 | 0 | 0.01 | 0.00 | -0.00 | hold |