| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 1,959,047 | 4,134,148 | +2,175,101 | 0.00 | 0.01 | +0.00 | buy |
| Decheng Capital LLC | 2,266,667 | 4,041,736 | +1,775,069 | 1.21 | 1.73 | +0.53 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 1,381,741 | +1,381,741 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 1,071,784 | 2,415,584 | +1,343,800 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 1,122,081 | +1,122,081 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 615,083 | 1,350,820 | +735,737 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 4,325,263 | 4,970,254 | +644,991 | 0.00 | 0.00 | -0.00 | buy |
| CANTOR FITZGERALD, L. P. | 100,000 | 695,573 | +595,573 | 0.01 | 0.04 | +0.03 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,744,147 | 2,195,191 | +451,044 | 0.01 | 0.01 | -0.00 | buy |
| JPMORGAN CHASE & CO | 88,320 | 498,721 | +410,401 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 789,597 | 1,182,737 | +393,140 | 0.00 | 0.00 | -0.00 | buy |
| Assenagon Asset Management S.A. | 397,362 | 681,553 | +284,191 | 0.00 | 0.00 | +0.00 | buy |
| Palo Alto Investors LP | 569,832 | 776,028 | +206,196 | 0.22 | 0.23 | +0.01 | buy |
| Graham Capital Management, L.P. | 14,172 | 177,558 | +163,386 | 0.00 | 0.01 | +0.01 | buy |
| Man Group plc | 53,534 | 197,748 | +144,214 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 428,587 | 555,953 | +127,366 | 0.00 | 0.00 | -0.00 | buy |
| OMERS ADMINISTRATION Corp | 54,400 | 175,900 | +121,500 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 239,595 | 354,849 | +115,254 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 15,201 | 119,001 | +103,800 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 1,257,779 | 1,361,037 | +103,258 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 850,519 | 951,394 | +100,875 | 0.00 | 0.00 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 154,351 | 250,805 | +96,454 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 175,175 | 269,086 | +93,911 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 319,275 | 407,525 | +88,250 | 0.00 | 0.00 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 70,502 | +70,502 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 67,933 | +67,933 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 292,892 | 348,917 | +56,025 | 0.00 | 0.00 | -0.00 | buy |
| HighTower Advisors, LLC | 262,948 | 316,064 | +53,116 | 0.00 | 0.00 | -0.00 | buy |
| Quantessence Capital LLC | 0 | 51,664 | +51,664 | 0.00 | 0.02 | +0.02 | buy |
| ExodusPoint Capital Management, LP | 10,637 | 59,865 | +49,228 | 0.00 | 0.00 | +0.00 | buy |
| LMR Partners LLP | 0 | 48,360 | +48,360 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 46,861 | +46,861 | 0.00 | 0.01 | +0.01 | buy |
| Invesco Ltd. | 11,215 | 57,079 | +45,864 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 41,723 | +41,723 | 0.00 | 0.03 | +0.03 | buy |
| Jain Global LLC | 24,460 | 65,672 | +41,212 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 39,850 | +39,850 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 39,331 | +39,331 | 0.00 | 0.00 | +0.00 | buy |
| Cannon Global Investment Management, LLC | 0 | 37,400 | +37,400 | 0.00 | 0.16 | +0.16 | buy |
| Verition Fund Management LLC | 0 | 35,805 | +35,805 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 30,516 | +30,516 | 0.00 | 0.00 | +0.00 | buy |
| Diametric Capital, LP | 0 | 30,137 | +30,137 | 0.00 | 0.05 | +0.05 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 29,316 | +29,316 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 25,189 | +25,189 | 0.00 | 0.00 | +0.00 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 23,564 | +23,564 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 57,760 | 78,782 | +21,022 | 0.00 | 0.00 | -0.00 | buy |
| HRT FINANCIAL LP | 0 | 17,286 | +17,286 | 0.00 | 0.00 | +0.00 | buy |
| Capula Management Ltd | 0 | 15,593 | +15,593 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 13,573 | +13,573 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 0 | 12,200 | +12,200 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 11,373 | +11,373 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 11,009 | +11,009 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 10,220 | +10,220 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 27,000 | 35,000 | +8,000 | 0.06 | 0.06 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 281,119 | 288,719 | +7,600 | 0.02 | 0.01 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,446 | 7,479 | +6,033 | 0.00 | 0.00 | +0.00 | buy |
| Vontobel Holding Ltd. | 16,000 | 22,000 | +6,000 | 0.00 | 0.00 | -0.00 | buy |
| Catalyst Funds Management Pty Ltd | 14,000 | 16,698 | +2,698 | 0.01 | 0.01 | -0.00 | buy |
| Point72 (DIFC) Ltd | 3,708 | 6,132 | +2,424 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 37,774 | 37,969 | +195 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 66 | 67 | +1 | 0.00 | 0.00 | -0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 9,627,304 | 9,627,304 | 0 | 0.04 | 0.03 | -0.01 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 4,666,667 | 4,666,667 | 0 | 0.15 | 0.12 | -0.03 | hold |
| Cambridge Investment Research Advisors, Inc. | 41,873 | 41,873 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Neuberger Berman Group LLC | 12,656 | 12,656 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Capital Advisors, Ltd. LLC | 454 | 454 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BML Capital Management, LLC | 14,250,000 | 14,250,000 | 0 | 21.95 | 17.65 | -4.31 | hold |
| Monashee Investment Management LLC | 888,888 | 888,888 | 0 | 0.30 | 0.16 | -0.14 | hold |
| Vivo Capital, LLC | 8,888,888 | 8,888,888 | 0 | 2.47 | 1.80 | -0.67 | hold |
| Truvestments Capital LLC | 150 | 150 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aisling Capital Management LP | 434,455 | 434,455 | 0 | 0.38 | 0.23 | -0.15 | hold |
| Logos Global Management LP | 2,222,222 | 2,222,222 | 0 | 0.64 | 0.60 | -0.04 | hold |
| Farther Finance Advisors, LLC | 99 | 99 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Marex Group plc | 14,400 | 14,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 14,694 | 14,694 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 123,100 | 123,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 33,079 | 33,079 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NISA INVESTMENT ADVISORS, LLC | 318 | 318 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 923,313 | 923,313 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Jefferies Financial Group Inc. | 40,700 | 40,200 | -500 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 610 | 0 | -610 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 2,765 | 2,094 | -671 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 459,049 | 458,184 | -865 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 4,292 | 2,942 | -1,350 | 0.00 | 0.00 | -0.00 | sell |
| MAI Capital Management | 1,500 | 0 | -1,500 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 48,187 | 45,659 | -2,528 | 0.03 | 0.02 | -0.01 | sell |
| Schonfeld Strategic Advisors LLC | 131,895 | 127,592 | -4,303 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 6,695 | 0 | -6,695 | 0.00 | 0.00 | -0.00 | sell |
| Aldebaran Capital, LLC | 1,016,958 | 1,007,958 | -9,000 | 2.40 | 1.46 | -0.94 | sell |
| Tower Research Capital LLC (TRC) | 17,919 | 3,413 | -14,506 | 0.00 | 0.00 | -0.00 | sell |
| Alpine Global Management, LLC | 15,340 | 0 | -15,340 | 0.01 | 0.00 | -0.01 | sell |
| Caption Management, LLC | 17,960 | 0 | -17,960 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 839,270 | 820,264 | -19,006 | 0.00 | 0.00 | -0.00 | sell |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 27,200 | 0 | -27,200 | 0.00 | 0.00 | -0.00 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 908,819 | 865,011 | -43,808 | 0.01 | 0.01 | -0.00 | sell |
| XTX Topco Ltd | 44,685 | 0 | -44,685 | 0.01 | 0.00 | -0.01 | sell |
| Engineers Gate Manager LP | 93,547 | 40,242 | -53,305 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 59,972 | 6,149 | -53,823 | 0.00 | 0.00 | -0.00 | sell |
| Marquette Asset Management, LLC | 57,911 | 0 | -57,911 | 0.02 | 0.00 | -0.02 | sell |