| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ACADIAN ASSET MANAGEMENT LLC | 0 | 2,351,407 | +2,351,407 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 3,357,240 | 5,388,789 | +2,031,549 | 0.02 | 0.01 | -0.02 | buy |
| D. E. Shaw & Co., Inc. | 66,010 | 1,939,010 | +1,873,000 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 0 | 1,761,595 | +1,761,595 | 0.00 | 1.31 | +1.31 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 1,753,335 | +1,753,335 | 0.00 | 0.17 | +0.17 | buy |
| Qube Research & Technologies Ltd | 0 | 1,679,905 | +1,679,905 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 37,969 | 1,587,995 | +1,550,026 | 0.02 | 0.14 | +0.12 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,967,980 | 3,479,361 | +1,511,381 | 0.01 | 0.00 | -0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 25,900 | 1,463,461 | +1,437,561 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 3,363,046 | 4,722,357 | +1,359,311 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 146,000 | 1,421,000 | +1,275,000 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 647,652 | 1,746,432 | +1,098,780 | 0.01 | 0.00 | -0.00 | buy |
| Monaco Asset Management SAM | 0 | 979,399 | +979,399 | 0.00 | 0.40 | +0.40 | buy |
| DEUTSCHE BANK AG\ | 154,309 | 934,046 | +779,737 | 0.00 | 0.00 | -0.00 | buy |
| BML Capital Management, LLC | 0 | 653,107 | +653,107 | 0.00 | 0.54 | +0.54 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 175,481 | 748,775 | +573,294 | 0.01 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 11,864 | 507,508 | +495,644 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 378,300 | +378,300 | 0.00 | 0.09 | +0.09 | buy |
| GOLDMAN SACHS GROUP INC | 272,821 | 520,880 | +248,059 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 76,610 | 217,354 | +140,744 | 0.00 | 0.00 | -0.00 | buy |
| STRS OHIO | 54,100 | 193,000 | +138,900 | 0.00 | 0.00 | -0.00 | buy |
| Man Group plc | 0 | 101,280 | +101,280 | 0.00 | 0.00 | -0.00 | buy |
| Bain Capital Life Sciences Investors, LLC | 3,400,000 | 3,500,000 | +100,000 | 2.60 | 0.35 | -2.25 | buy |
| Octagon Capital Advisors LP | 0 | 100,000 | +100,000 | 0.00 | 0.02 | +0.02 | buy |
| JANE STREET GROUP, LLC | 164,060 | 259,384 | +95,324 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 43,024 | 135,295 | +92,271 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,337,082 | 1,393,548 | +56,466 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 25,470 | 79,789 | +54,319 | 0.01 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 242,770 | 282,371 | +39,601 | 0.00 | 0.00 | -0.00 | buy |
| Mariner, LLC | 0 | 36,657 | +36,657 | 0.00 | 0.00 | +0.00 | buy |
| Cambridge Investment Research Advisors, Inc. | 15,338 | 41,873 | +26,535 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,317 | 43,784 | +23,467 | 0.00 | 0.00 | -0.00 | buy |
| Chicago Partners Investment Group LLC | 0 | 20,988 | +20,988 | 0.00 | 0.00 | +0.00 | buy |
| WEXFORD CAPITAL LP | 0 | 20,000 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 0 | 19,482 | +19,482 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Middle East FZE | 10,692 | 29,344 | +18,652 | 0.00 | 0.00 | -0.00 | buy |
| Neuberger Berman Group LLC | 0 | 18,219 | +18,219 | 0.00 | 0.00 | +0.00 | buy |
| Bayesian Capital Management, LP | 0 | 17,800 | +17,800 | 0.00 | 0.00 | +0.00 | buy |
| Vontobel Holding Ltd. | 13,228 | 30,268 | +17,040 | 0.00 | 0.00 | -0.00 | buy |
| Marex Group plc | 0 | 14,400 | +14,400 | 0.00 | 0.00 | +0.00 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 13,504 | +13,504 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 10,378 | +10,378 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 661,300 | 670,714 | +9,414 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 68,290 | 77,201 | +8,911 | 0.02 | 0.00 | -0.02 | buy |
| China Universal Asset Management Co., Ltd. | 1,814 | 8,196 | +6,382 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,264 | 9,744 | +5,480 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 4,583 | +4,583 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 13,659 | 16,020 | +2,361 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 33 | 1,170 | +1,137 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 18,765 | 19,419 | +654 | 0.00 | 0.00 | -0.00 | buy |
| HUNTINGTON NATIONAL BANK | 0 | 334 | +334 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 659,371 | 659,637 | +266 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 65 | +65 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 7 | 14 | +7 | 0.00 | 0.00 | 0.00 | buy |
| CANADA LIFE ASSURANCE Co | 1,944 | 1,944 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 6,900 | 6,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 60,400 | 60,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AdvisorNet Financial, Inc | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Daiwa Securities Group Inc. | 248 | 248 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Swiss National Bank | 108,900 | 108,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Lion Point Capital, LP | 115,898 | 115,898 | 0 | 0.73 | 0.11 | -0.62 | hold |
| Samsara BioCapital, LLC | 696,171 | 696,171 | 0 | 1.46 | 0.11 | -1.35 | hold |
| Truvestments Capital LLC | 150 | 150 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aisling Capital Management LP | 434,455 | 434,455 | 0 | 1.23 | 0.14 | -1.09 | hold |
| Frazier Life Sciences Management, L.P. | 264,377 | 264,377 | 0 | 0.12 | 0.01 | -0.11 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 49,895 | 49,895 | 0 | 0.00 | 0.00 | -0.00 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 113,601 | 113,601 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TUDOR INVESTMENT CORP ET AL | 33,183 | 33,183 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 20,094 | 20,094 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Baker Avenue Asset Management, LP | 34 | 0 | -34 | 0.00 | 0.00 | -0.00 | sell |
| Allworth Financial LP | 38 | 0 | -38 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 96 | 48 | -48 | 0.00 | 0.00 | -0.00 | sell |
| JANUS HENDERSON GROUP PLC | 20,353 | 20,300 | -53 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 34,661 | 34,523 | -138 | 0.00 | 0.00 | -0.00 | sell |
| SIGNATUREFD, LLC | 161 | 0 | -161 | 0.00 | 0.00 | -0.00 | sell |
| Arizona State Retirement System | 14,087 | 13,853 | -234 | 0.00 | 0.00 | -0.00 | sell |
| QUADRANT CAPITAL GROUP LLC | 365 | 0 | -365 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 10,484 | 9,798 | -686 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 1,067 | 0 | -1,067 | 0.00 | 0.00 | -0.00 | sell |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 14,088 | 11,458 | -2,630 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 59,047 | 55,559 | -3,488 | 0.00 | 0.00 | -0.00 | sell |
| METROPOLITAN LIFE INSURANCE CO/NY | 3,901 | 0 | -3,901 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 102,434 | 95,750 | -6,684 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 39,718 | 31,657 | -8,061 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 10,511 | 0 | -10,511 | 0.00 | 0.00 | -0.00 | sell |
| J. Goldman & Co LP | 11,456 | 0 | -11,456 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 27,974 | 15,960 | -12,014 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 77,515 | 64,760 | -12,755 | 0.00 | 0.00 | -0.00 | sell |
| Pale Fire Capital SE | 13,000 | 0 | -13,000 | 0.01 | 0.00 | -0.01 | sell |
| PROFUND ADVISORS LLC | 13,098 | 0 | -13,098 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 13,305 | 0 | -13,305 | 0.00 | 0.00 | -0.00 | sell |
| Dynamic Technology Lab Private Ltd | 14,135 | 0 | -14,135 | 0.01 | 0.00 | -0.01 | sell |
| CWA Asset Management Group, LLC | 14,705 | 0 | -14,705 | 0.01 | 0.00 | -0.01 | sell |
| Corton Capital Inc. | 14,916 | 0 | -14,916 | 0.05 | 0.00 | -0.05 | sell |
| Belvedere Trading LLC | 15,386 | 0 | -15,386 | 0.01 | 0.00 | -0.01 | sell |
| WELLS FARGO & COMPANY/MN | 18,287 | 0 | -18,287 | 0.00 | 0.00 | -0.00 | sell |
| CAXTON CORP | 19,473 | 0 | -19,473 | 0.51 | 0.00 | -0.51 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 27,043 | 7,155 | -19,888 | 0.00 | 0.00 | -0.00 | sell |