| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BML Capital Management, LLC | 14,250,000 | 14,250,000 | 0 | 24.91 | 37.97 | +13.06 | hold |
| Vivo Capital, LLC | 8,888,888 | 8,888,888 | 0 | 1.36 | 1.73 | +0.37 | hold |
| BlackRock, Inc. | 5,691,352 | 6,804,841 | +1,113,489 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 6,515,458 | 6,502,080 | -13,378 | 0.00 | 0.00 | +0.00 | sell |
| Rock Springs Capital Management LP | 4,609,309 | 4,453,741 | -155,568 | 0.51 | 0.69 | +0.18 | sell |
| Decheng Capital LLC | 4,041,736 | 4,041,736 | 0 | 1.34 | 1.64 | +0.30 | hold |
| MORGAN STANLEY | 4,077,246 | 3,415,390 | -661,856 | 0.00 | 0.00 | +0.00 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,278,144 | 3,371,000 | -1,907,144 | 0.02 | 0.02 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 2,389,531 | 2,392,772 | +3,241 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 2,327,019 | 2,122,399 | -204,620 | 0.01 | 0.01 | +0.00 | sell |
| D. E. Shaw & Co., Inc. | 2,373,226 | 2,096,651 | -276,575 | 0.00 | 0.00 | +0.00 | sell |
| Palo Alto Investors LP | 1,566,840 | 1,566,840 | 0 | 0.55 | 0.66 | +0.11 | hold |
| STATE STREET CORP | 1,113,146 | 1,506,403 | +393,257 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 1,067,656 | 1,434,164 | +366,508 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 1,432,677 | 1,205,281 | -227,396 | 0.00 | 0.00 | +0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,619,731 | 1,125,331 | -494,400 | 0.00 | 0.01 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 1,554,458 | 1,053,246 | -501,212 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 923,313 | 987,351 | +64,038 | 0.00 | 0.00 | +0.00 | buy |
| Aldebaran Capital, LLC | 987,698 | 954,262 | -33,436 | 1.72 | 2.58 | +0.85 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 916,846 | +916,846 | 0.00 | 0.00 | +0.00 | buy |
| Bollard Group LLC | 1,225,476 | 804,445 | -421,031 | 0.06 | 0.06 | +0.01 | sell |
| Woodline Partners LP | 0 | 742,009 | +742,009 | 0.00 | 0.01 | +0.01 | buy |
| Three Bridge Wealth Advisors, LLC | 714,823 | 714,823 | 0 | 0.35 | 0.57 | +0.22 | hold |
| NORTHERN TRUST CORP | 700,823 | 664,258 | -36,565 | 0.00 | 0.00 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 956,051 | 632,502 | -323,549 | 0.00 | 0.00 | +0.00 | sell |
| JPMORGAN CHASE & CO | 758,576 | 625,963 | -132,613 | 0.00 | 0.00 | +0.00 | sell |
| ADAR1 Capital Management, LLC | 373,682 | 613,986 | +240,304 | 0.07 | 0.14 | +0.07 | buy |
| Logos Global Management LP | 1,500,000 | 600,000 | -900,000 | 0.28 | 0.12 | -0.16 | sell |
| TWO SIGMA INVESTMENTS, LP | 368,107 | 574,213 | +206,106 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 1,718,130 | 485,501 | -1,232,629 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 544,760 | 447,175 | -97,585 | 0.00 | 0.00 | +0.00 | sell |
| Aisling Capital Management LP | 434,455 | 434,455 | 0 | 0.18 | 0.27 | +0.09 | hold |
| UBS Group AG | 0 | 362,538 | +362,538 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 393,319 | 330,019 | -63,300 | 0.02 | 0.02 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 1,277,817 | 318,426 | -959,391 | 0.00 | 0.00 | -0.00 | sell |
| HighTower Advisors, LLC | 309,317 | 305,948 | -3,369 | 0.00 | 0.00 | +0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 241,956 | 284,604 | +42,648 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 164,244 | 270,850 | +106,606 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 283,476 | 269,684 | -13,792 | 0.00 | 0.00 | +0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 264,359 | +264,359 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 350,100 | 255,400 | -94,700 | 0.00 | 0.00 | +0.00 | sell |
| Nuveen, LLC | 237,830 | 237,830 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Invesco Ltd. | 162,463 | 209,903 | +47,440 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 220,082 | 203,517 | -16,565 | 0.00 | 0.00 | +0.00 | sell |
| Assenagon Asset Management S.A. | 154,554 | 154,554 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BARCLAYS PLC | 123,425 | 143,414 | +19,989 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 140,167 | 140,167 | 0 | 0.00 | 0.00 | +0.00 | hold |
| XTX Topco Ltd | 63,925 | 112,912 | +48,987 | 0.01 | 0.01 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 68,039 | 104,465 | +36,426 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 34,952 | 103,792 | +68,840 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 88,966 | +88,966 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 87,175 | +87,175 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 31,788 | 77,568 | +45,780 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 91,236 | 71,804 | -19,432 | 0.00 | 0.00 | +0.00 | sell |
| PANAGORA ASSET MANAGEMENT INC | 45,585 | 68,190 | +22,605 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 31,553 | 57,670 | +26,117 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 51,171 | +51,171 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 38,944 | 46,646 | +7,702 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 40,350 | 45,807 | +5,457 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 42,755 | 42,568 | -187 | 0.00 | 0.00 | +0.00 | sell |
| Man Group plc | 0 | 42,435 | +42,435 | 0.00 | 0.00 | +0.00 | buy |
| Cambridge Investment Research Advisors, Inc. | 41,873 | 41,873 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CITIGROUP INC | 1,935 | 41,630 | +39,695 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 39,701 | +39,701 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 33,500 | 28,998 | -4,502 | 0.00 | 0.00 | +0.00 | sell |
| Valeo Financial Advisors, LLC | 0 | 27,540 | +27,540 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 48,400 | 27,300 | -21,100 | 0.00 | 0.00 | -0.00 | sell |
| Vontobel Holding Ltd. | 26,000 | 26,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MetLife Investment Management, LLC | 35,317 | 25,597 | -9,720 | 0.00 | 0.00 | +0.00 | sell |
| AXQ CAPITAL, LP | 13,969 | 24,186 | +10,217 | 0.01 | 0.02 | +0.01 | buy |
| Persistent Asset Partners Ltd | 0 | 22,259 | +22,259 | 0.00 | 0.03 | +0.03 | buy |
| ProShare Advisors LLC | 14,819 | 21,553 | +6,734 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 26,667 | 21,516 | -5,151 | 0.00 | 0.00 | +0.00 | sell |
| Police & Firemen's Retirement System of New Jersey | 19,700 | 19,700 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Neuberger Berman Group LLC | 12,704 | 18,955 | +6,251 | 0.00 | 0.00 | +0.00 | buy |
| CRA Financial Services, LLC | 17,782 | 17,782 | 0 | 0.00 | 0.01 | +0.00 | hold |
| China Universal Asset Management Co., Ltd. | 0 | 17,655 | +17,655 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Asset Management Inc | 0 | 17,428 | +17,428 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 17,248 | 17,248 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Mariner, LLC | 16,112 | 16,670 | +558 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 16,668 | +16,668 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 22,012 | 15,423 | -6,589 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 15,200 | 15,200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GROUP ONE TRADING LLC | 1,748 | 12,433 | +10,685 | 0.00 | 0.00 | +0.00 | buy |
| R Squared Ltd | 0 | 12,408 | +12,408 | 0.00 | 0.02 | +0.02 | buy |
| TWO SIGMA SECURITIES, LLC | 10,586 | 11,545 | +959 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 11,000 | 11,002 | +2 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 10,628 | 10,651 | +23 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 10,460 | 10,167 | -293 | 0.00 | 0.00 | +0.00 | sell |
| Russell Investments Group, Ltd. | 9,612 | 9,785 | +173 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 9,267 | 9,267 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 8,242 | 8,242 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 5,668 | 5,649 | -19 | 0.00 | 0.00 | +0.00 | sell |
| Sterling Capital Management LLC | 5,980 | 5,288 | -692 | 0.00 | 0.00 | +0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 0 | 5,265 | +5,265 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 6,500 | 3,750 | -2,750 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 3,100 | 2,883 | -217 | 0.00 | 0.00 | +0.00 | sell |
| GF FUND MANAGEMENT CO. LTD. | 0 | 2,128 | +2,128 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 0 | 1,226 | +1,226 | 0.00 | 0.00 | +0.00 | buy |
| Motiv8 Investments LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |