| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Velan Capital Investment Management LP | 0 | 747,410 | +747,410 | 0.00 | 0.94 | +0.94 | buy |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 0 | 200,000 | +200,000 | 0.00 | 0.01 | +0.01 | buy |
| Nantahala Capital Management, LLC | 3,679,726 | 3,877,965 | +198,239 | 0.78 | 0.39 | -0.39 | buy |
| VANGUARD GROUP INC | 1,875,579 | 1,928,173 | +52,594 | 0.00 | 0.00 | -0.00 | buy |
| Atom Investors LP | 0 | 48,110 | +48,110 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 311,405 | 346,668 | +35,263 | 0.00 | 0.00 | -0.00 | buy |
| Birchview Capital, LP | 125,000 | 155,000 | +30,000 | 0.31 | 0.16 | -0.14 | buy |
| Rollins Financial Advisors, LLC | 0 | 18,656 | +18,656 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 47,181 | 64,799 | +17,618 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 0 | 12,769 | +12,769 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 0 | 10,352 | +10,352 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 10,156 | +10,156 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 50,700 | 57,500 | +6,800 | 0.00 | 0.00 | -0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 3,667 | +3,667 | 0.00 | 0.00 | +0.00 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 907,865 | 910,615 | +2,750 | 2.43 | 1.17 | -1.26 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 1,991 | +1,991 | 0.00 | 0.00 | +0.00 | buy |
| Embree Financial Group | 12,500 | 14,000 | +1,500 | 0.01 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 563 | +563 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 310 | +310 | 0.00 | 0.00 | 0.00 | buy |
| BARCLAYS PLC | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| DAFNA Capital Management LLC | 1,441,029 | 1,441,029 | 0 | 1.11 | 0.50 | -0.61 | hold |
| Sio Capital Management, LLC | 630,000 | 630,000 | 0 | 0.54 | 0.23 | -0.30 | hold |
| Essex Woodlands Management, Inc. | 4,110,709 | 4,110,709 | 0 | 2.87 | 1.45 | -1.42 | hold |
| OCCUDO QUANTITATIVE STRATEGIES LP | 19,960 | 19,960 | 0 | 0.01 | 0.00 | -0.01 | hold |
| UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC | 99,888 | 99,888 | 0 | 0.30 | 0.11 | -0.19 | hold |
| Mink Brook Asset Management LLC | 357,092 | 357,092 | 0 | 1.03 | 0.46 | -0.57 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 28,441 | 28,441 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PNC FINANCIAL SERVICES GROUP, INC. | 53,612 | 53,612 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITIGROUP INC | 750,000 | 750,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 314 | 224 | -90 | 0.00 | 0.00 | -0.00 | sell |
| Capital Advisors, Ltd. LLC | 130 | 0 | -130 | 0.00 | 0.00 | 0.00 | sell |
| SBI Securities Co., Ltd. | 701 | 371 | -330 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 337 | 0 | -337 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 923 | 0 | -923 | 0.00 | 0.00 | -0.00 | sell |
| Pentwater Capital Management LP | 1,000,000 | 998,755 | -1,245 | 0.05 | 0.02 | -0.04 | sell |
| BlackRock, Inc. | 427,528 | 425,866 | -1,662 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 65,483 | 63,383 | -2,100 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 2,800 | 0 | -2,800 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 6,302 | 0 | -6,302 | 0.01 | 0.00 | -0.01 | sell |
| PRUDENTIAL FINANCIAL INC | 18,800 | 12,200 | -6,600 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 12,087 | 0 | -12,087 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 30,138 | 15,301 | -14,837 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 133,666 | 108,367 | -25,299 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 31,313 | 0 | -31,313 | 0.00 | 0.00 | -0.00 | sell |
| Diametric Capital, LP | 35,755 | 0 | -35,755 | 0.07 | 0.00 | -0.07 | sell |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 40,088 | 0 | -40,088 | 0.01 | 0.00 | -0.01 | sell |
| CITADEL ADVISORS LLC | 56,510 | 0 | -56,510 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 60,476 | 0 | -60,476 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 135,754 | 40,664 | -95,090 | 0.03 | 0.00 | -0.03 | sell |
| Archon Capital Management LLC | 150,000 | 0 | -150,000 | 0.55 | 0.00 | -0.55 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 425,140 | 244,444 | -180,696 | 0.00 | 0.00 | -0.00 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 3,065,649 | 2,771,288 | -294,361 | 2.07 | 0.71 | -1.36 | sell |
| Stonepine Capital Management, LLC | 2,353,099 | 2,055,225 | -297,874 | 5.74 | 2.44 | -3.30 | sell |
| UBS Group AG | 767,830 | 330,683 | -437,147 | 0.00 | 0.00 | -0.00 | sell |
| ROYCE & ASSOCIATES LP | 1,000,064 | 0 | -1,000,064 | 0.03 | 0.00 | -0.03 | sell |
| AIGH Capital Management LLC | 2,662,785 | 1,416,323 | -1,246,462 | 3.03 | 0.90 | -2.13 | sell |