| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 2,072,813 | 1,580,000 | +492,813 | 6.61 | 3.83 | -2.78 | sell |
| Pentwater Capital Management LP | 490,402 | 878,799 | +388,397 | 0.09 | 0.11 | +0.02 | buy |
| PURA VIDA INVESTMENTS, LLC | 371,809 | 402,016 | +30,207 | 0.40 | 1.69 | +1.29 | buy |
| Parkman Healthcare Partners LLC | 137,372 | 159,026 | +21,654 | 0.32 | 0.28 | 0.00 | buy |
| TOWNSQUARE CAPITAL LLC | 48,976 | 59,543 | +10,567 | 0.01 | 0.01 | 0.00 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 777,753 | 774,912 | +2,841 | 0.91 | 0.76 | 0.00 | sell |
| SANDERS MORRIS HARRIS LLC | 69,168 | 68,168 | -1,000 | 0.26 | 0.15 | -0.10 | sell |