| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,097,866 | 2,445,667 | +1,347,801 | 0.61 | 1.15 | +0.54 | buy |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 515,265 | 1,256,200 | +740,935 | 0.14 | 0.27 | +0.13 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 404,578 | +404,578 | 0.00 | 0.00 | +0.00 | buy |
| AIGH Capital Management LLC | 1,415,255 | 1,656,655 | +241,400 | 3.87 | 3.80 | -0.07 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 776,851 | 1,000,000 | +223,149 | 1.24 | 1.16 | -0.07 | buy |
| CITADEL ADVISORS LLC | 0 | 189,703 | +189,703 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 12,609 | 153,749 | +141,140 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 100,036 | +100,036 | 0.00 | 0.00 | +0.00 | buy |
| Pentwater Capital Management LP | 308,642 | 400,000 | +91,358 | 0.03 | 0.04 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 87,320 | +87,320 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 78,300 | +78,300 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 64,289 | +64,289 | 0.00 | 0.01 | +0.01 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 63,316 | +63,316 | 0.00 | 0.02 | +0.02 | buy |
| Trexquant Investment LP | 0 | 40,390 | +40,390 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 34,192 | +34,192 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 29,000 | +29,000 | 0.00 | 0.01 | +0.01 | buy |
| Atom Investors LP | 35,613 | 64,359 | +28,746 | 0.03 | 0.03 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 28,028 | +28,028 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 27,772 | +27,772 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 24,433 | +24,433 | 0.00 | 0.02 | +0.02 | buy |
| HRT FINANCIAL LP | 0 | 21,229 | +21,229 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 37,000 | 53,000 | +16,000 | 0.00 | 0.01 | +0.00 | buy |
| Paloma Partners Management Co | 0 | 12,200 | +12,200 | 0.00 | 0.00 | +0.00 | buy |
| Ground Swell Capital, LLC | 0 | 11,319 | +11,319 | 0.00 | 0.05 | +0.05 | buy |
| Virtu Financial LLC | 0 | 11,055 | +11,055 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 10,315 | +10,315 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,736 | 7,717 | +5,981 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 5,385 | +5,385 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 6,685 | 10,794 | +4,109 | 0.00 | 0.00 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 4,000 | +4,000 | 0.00 | 0.01 | +0.01 | buy |
| Meros Investment Management, LP | 150,339 | 152,718 | +2,379 | 0.38 | 0.34 | -0.04 | buy |
| MACQUARIE GROUP LTD | 0 | 805 | +805 | 0.00 | 0.00 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 97,668 | 97,816 | +148 | 0.07 | 0.06 | -0.01 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 108 | +108 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 60 | +60 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 337 | 376 | +39 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 712,300 | 712,300 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Essex Woodlands Management, Inc. | 4,110,709 | 4,110,709 | 0 | 6.76 | 6.30 | -0.46 | hold |
| BFSG, LLC | 525 | 525 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Velan Capital Investment Management LP | 746,087 | 746,087 | 0 | 2.29 | 2.01 | -0.28 | hold |
| UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC | 11,000 | 11,000 | 0 | 0.10 | 0.08 | -0.02 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 14,886 | 14,886 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avior Wealth Management, LLC | 3 | 0 | -3 | 0.00 | 0.00 | -0.00 | sell |
| NewEdge Advisors, LLC | 5 | 0 | -5 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 53,739 | 53,612 | -127 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 2,669 | 2,186 | -483 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 535 | 0 | -535 | 0.00 | 0.00 | -0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 383,075 | 381,919 | -1,156 | 0.04 | 0.04 | -0.01 | sell |
| Ameritas Investment Partners, Inc. | 1,311 | 0 | -1,311 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 24,385 | 22,493 | -1,892 | 0.01 | 0.01 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 35,000 | 33,090 | -1,910 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 1,937 | 0 | -1,937 | 0.00 | 0.00 | -0.00 | sell |
| Worth Venture Partners, LLC | 3,860 | 0 | -3,860 | 0.15 | 0.00 | -0.15 | sell |
| PERKINS CAPITAL MANAGEMENT INC | 210,000 | 204,350 | -5,650 | 0.99 | 0.90 | -0.09 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 7,975 | 0 | -7,975 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 9,610 | 136 | -9,474 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 11,437 | 143 | -11,294 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 132,988 | 121,329 | -11,659 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 15,095 | 2,499 | -12,596 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 16,381 | 0 | -16,381 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 33,464 | 15,672 | -17,792 | 0.03 | 0.01 | -0.02 | sell |
| Calamos Advisors LLC | 33,776 | 0 | -33,776 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 42,385 | 0 | -42,385 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 42,911 | 0 | -42,911 | 0.00 | 0.00 | -0.00 | sell |
| Stonepine Capital Management, LLC | 688,200 | 625,645 | -62,555 | 3.10 | 2.68 | -0.41 | sell |
| Russell Investments Group, Ltd. | 94,940 | 188 | -94,752 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,006,052 | 903,503 | -102,549 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 349,723 | 179,964 | -169,759 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 193,811 | 7,800 | -186,011 | 0.68 | 0.02 | -0.66 | sell |
| STATE STREET CORP | 375,368 | 107,435 | -267,933 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 2,835,542 | 2,457,542 | -378,000 | 0.30 | 0.23 | -0.07 | sell |
| First Light Asset Management, LLC | 2,754,028 | 0 | -2,754,028 | 1.20 | 0.00 | -1.20 | sell |