| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| AIGH Capital Management LLC | 1,656,655 | 2,469,373 | +812,718 | 3.80 | 2.92 | -0.88 | buy |
| CITIGROUP INC | 2,186 | 750,000 | +747,814 | 0.00 | 0.00 | +0.00 | buy |
| Stonepine Capital Management, LLC | 625,645 | 1,110,000 | +484,355 | 2.68 | 1.77 | -0.91 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 191,400 | +191,400 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 143,199 | +143,199 | 0.00 | 0.04 | +0.04 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1,000,000 | 1,124,928 | +124,928 | 1.16 | 0.64 | -0.52 | buy |
| MARSHALL WACE, LLP | 0 | 106,804 | +106,804 | 0.00 | 0.00 | +0.00 | buy |
| Pentwater Capital Management LP | 400,000 | 500,000 | +100,000 | 0.04 | 0.02 | -0.02 | buy |
| GSA CAPITAL PARTNERS LLP | 22,493 | 112,205 | +89,712 | 0.01 | 0.02 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 78,300 | 148,900 | +70,600 | 0.00 | 0.00 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 53,000 | 103,000 | +50,000 | 0.01 | 0.01 | -0.00 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 204,350 | 225,200 | +20,850 | 0.90 | 0.53 | -0.37 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 19,345 | +19,345 | 0.00 | 0.01 | +0.01 | buy |
| Trexquant Investment LP | 40,390 | 51,472 | +11,082 | 0.00 | 0.00 | -0.00 | buy |
| Embree Financial Group | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,888 | +1,888 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 746,087 | 747,410 | +1,323 | 2.01 | 2.05 | +0.04 | buy |
| Capital Advisors, Ltd. LLC | 0 | 130 | +130 | 0.00 | 0.00 | 0.00 | buy |
| VANGUARD GROUP INC | 903,503 | 903,503 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Essex Woodlands Management, Inc. | 4,110,709 | 4,110,709 | 0 | 6.30 | 2.97 | -3.33 | hold |
| Arax Advisory Partners | 60 | 60 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BFSG, LLC | 525 | 525 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Catalyst Funds Management Pty Ltd | 4,000 | 4,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC | 11,000 | 11,000 | 0 | 0.08 | 0.03 | -0.05 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 14,886 | 14,886 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PNC FINANCIAL SERVICES GROUP, INC. | 53,612 | 53,612 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Farther Finance Advisors, LLC | 13 | 0 | -13 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 376 | 337 | -39 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 108 | 0 | -108 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 136 | 0 | -136 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 143 | 0 | -143 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 188 | 0 | -188 | 0.00 | 0.00 | -0.00 | sell |
| MACQUARIE GROUP LTD | 805 | 0 | -805 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 2,499 | 0 | -2,499 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 15,672 | 12,549 | -3,123 | 0.01 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 7,800 | 2,800 | -5,000 | 0.02 | 0.00 | -0.02 | sell |
| Point72 (DIFC) Ltd | 5,385 | 0 | -5,385 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 179,964 | 174,515 | -5,449 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 7,717 | 1,717 | -6,000 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 8,135 | 0 | -8,135 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 10,315 | 0 | -10,315 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 10,794 | 0 | -10,794 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 11,055 | 0 | -11,055 | 0.00 | 0.00 | -0.00 | sell |
| Ground Swell Capital, LLC | 11,319 | 0 | -11,319 | 0.05 | 0.00 | -0.05 | sell |
| Paloma Partners Management Co | 12,200 | 0 | -12,200 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 24,433 | 11,558 | -12,875 | 0.02 | 0.01 | -0.02 | sell |
| Squarepoint Ops LLC | 28,028 | 13,422 | -14,606 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 33,090 | 12,200 | -20,890 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 21,229 | 0 | -21,229 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 34,192 | 10,113 | -24,079 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 27,772 | 0 | -27,772 | 0.00 | 0.00 | -0.00 | sell |
| Centiva Capital, LP | 29,000 | 0 | -29,000 | 0.01 | 0.00 | -0.01 | sell |
| STATE STREET CORP | 107,435 | 65,483 | -41,952 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 64,289 | 16,030 | -48,259 | 0.01 | 0.00 | -0.00 | sell |
| Y-Intercept (Hong Kong) Ltd | 63,316 | 0 | -63,316 | 0.02 | 0.00 | -0.02 | sell |
| Atom Investors LP | 64,359 | 0 | -64,359 | 0.03 | 0.00 | -0.03 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 87,320 | 0 | -87,320 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 121,329 | 31,325 | -90,004 | 0.00 | 0.00 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 97,816 | 0 | -97,816 | 0.06 | 0.00 | -0.06 | sell |
| JANE STREET GROUP, LLC | 100,036 | 0 | -100,036 | 0.00 | 0.00 | -0.00 | sell |
| Meros Investment Management, LP | 152,718 | 0 | -152,718 | 0.34 | 0.00 | -0.34 | sell |
| GOLDMAN SACHS GROUP INC | 153,749 | 0 | -153,749 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 189,703 | 0 | -189,703 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 404,578 | 159,052 | -245,526 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 2,457,542 | 2,161,185 | -296,357 | 0.23 | 0.10 | -0.13 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 381,919 | 0 | -381,919 | 0.04 | 0.00 | -0.04 | sell |
| Nantahala Capital Management, LLC | 2,445,667 | 1,915,126 | -530,541 | 1.15 | 0.41 | -0.75 | sell |
| FEDERATED HERMES, INC. | 712,300 | 0 | -712,300 | 0.01 | 0.00 | -0.01 | sell |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 1,256,200 | 0 | -1,256,200 | 0.27 | 0.00 | -0.27 | sell |