| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Essex Woodlands Management, Inc. | 4,110,709 | 7,714,709 | +3,604,000 | 1.99 | 2.86 | +0.87 | buy |
| UBS Group AG | 0 | 1,500,469 | +1,500,469 | 0.00 | 0.00 | +0.00 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 833,928 | 1,397,418 | +563,490 | 1.10 | 1.31 | +0.21 | buy |
| Stonepine Capital Management, LLC | 2,155,519 | 2,352,032 | +196,513 | 2.61 | 2.20 | -0.42 | buy |
| Embree Financial Group | 14,000 | 111,318 | +97,318 | 0.00 | 0.02 | +0.01 | buy |
| WealthTrust Axiom LLC | 231,938 | 322,588 | +90,650 | 0.09 | 0.10 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 63,900 | 128,700 | +64,800 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 40,955 | +40,955 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,799,884 | 1,830,550 | +30,666 | 0.00 | 0.00 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 20,817 | +20,817 | 0.00 | 0.00 | +0.00 | buy |
| GREAT VALLEY ADVISOR GROUP, INC. | 0 | 19,602 | +19,602 | 0.00 | 0.00 | +0.00 | buy |
| NINE MASTS CAPITAL Ltd | 0 | 16,486 | +16,486 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 10,663 | +10,663 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 20,200 | 30,200 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 356,721 | 361,498 | +4,777 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 460,606 | 462,353 | +1,747 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 57,500 | 57,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 210 | 210 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DAFNA Capital Management LLC | 1,441,029 | 1,441,029 | 0 | 0.53 | 0.39 | -0.14 | hold |
| HighTower Advisors, LLC | 10,352 | 10,352 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Nantahala Capital Management, LLC | 5,111,588 | 5,111,588 | 0 | 0.47 | 0.36 | -0.11 | hold |
| Sio Capital Management, LLC | 636,300 | 636,300 | 0 | 0.24 | 0.12 | -0.12 | hold |
| Steward Partners Investment Advisory, LLC | 1,991 | 1,991 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Destiny Wealth Partners, LLC | 52,500 | 52,500 | 0 | 0.01 | 0.01 | -0.00 | hold |
| UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC | 99,888 | 99,888 | 0 | 0.11 | 0.06 | -0.05 | hold |
| PNC FINANCIAL SERVICES GROUP, INC. | 53,612 | 53,612 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITIGROUP INC | 750,000 | 750,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 63,383 | 63,383 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 302 | 301 | -1 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 175,319 | 174,398 | -921 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 105,809 | 73,811 | -31,998 | 0.01 | 0.01 | -0.01 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 2,782,923 | 2,647,512 | -135,411 | 0.60 | 0.45 | -0.15 | sell |
| Birchview Capital, LP | 155,000 | 0 | -155,000 | 0.17 | 0.00 | -0.17 | sell |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 200,000 | 0 | -200,000 | 0.01 | 0.00 | -0.01 | sell |
| Pentwater Capital Management LP | 724,856 | 0 | -724,856 | 0.01 | 0.00 | -0.01 | sell |
| Velan Capital Investment Management LP | 747,410 | 0 | -747,410 | 1.05 | 0.00 | -1.05 | sell |