| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 63,111 | 86,643 | +23,532 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | 18,298 | +18,298 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 65,034 | 65,147 | +113 | 0.01 | 0.01 | -0.00 | buy |
| BARCLAYS PLC | 0 | 100 | +100 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 443,518 | 443,518 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Palo Alto Investors LP | 445,434 | 445,434 | 0 | 0.10 | 0.11 | +0.01 | hold |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,394,336 | 1,394,336 | 0 | 0.05 | 0.05 | +0.00 | hold |
| Cormorant Asset Management, LP | 1,394,336 | 1,394,336 | 0 | 0.16 | 0.14 | -0.02 | hold |
| Russell Investments Group, Ltd. | 187 | 187 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Centerpoint Advisors, LLC | 350 | 350 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Lynx1 Capital Management LP | 16,194 | 16,194 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Exome Asset Management LLC | 353,434 | 353,434 | 0 | 0.62 | 0.45 | -0.17 | hold |
| MB, LEVIS & ASSOCIATES, LLC | 1,041 | 1,041 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 15,765 | 15,765 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHERN TRUST CORP | 37,655 | 37,290 | -365 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 135,670 | 134,590 | -1,080 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 3,383 | 2,209 | -1,174 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 171,217 | 152,865 | -18,352 | 0.07 | 0.05 | -0.02 | sell |
| CITADEL ADVISORS LLC | 1,211,066 | 1,187,413 | -23,653 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 216,223 | 168,600 | -47,623 | 0.00 | 0.00 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 345,206 | 202,973 | -142,233 | 0.09 | 0.05 | -0.04 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 467,397 | 76,784 | -390,613 | 0.23 | 0.03 | -0.19 | sell |