| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 19,698,442 | 19,737,215 | +38,773 | 0.00 | 0.01 | +0.00 | buy |
| BlackRock, Inc. | 16,587,213 | 15,759,450 | -827,763 | 0.00 | 0.01 | +0.00 | sell |
| T. Rowe Price Investment Management, Inc. | 11,826,245 | 12,651,262 | +825,017 | 0.10 | 0.17 | +0.07 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 11,840,818 | 11,649,591 | -191,227 | 3.08 | 4.53 | +1.46 | sell |
| JPMORGAN CHASE & CO | 13,830,100 | 9,923,588 | -3,906,512 | 0.01 | 0.01 | +0.00 | sell |
| Thrive Capital Management, LLC | 6,343,617 | 6,343,617 | 0 | 14.12 | 57.61 | +43.49 | hold |
| STATE STREET CORP | 5,784,092 | 5,400,482 | -383,610 | 0.00 | 0.00 | +0.00 | sell |
| GILDER GAGNON HOWE & CO LLC | 6,281,817 | 4,909,743 | -1,372,074 | 1.08 | 1.12 | +0.04 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 4,684,380 | 4,506,118 | -178,262 | 0.00 | 0.01 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 3,571,070 | 3,686,980 | +115,910 | 0.01 | 0.02 | +0.01 | buy |
| Capital World Investors | 3,622,586 | 3,622,586 | 0 | 0.01 | 0.01 | +0.00 | hold |
| GLYNN CAPITAL MANAGEMENT LLC | 3,115,217 | 3,009,778 | -105,439 | 10.74 | 14.51 | +3.76 | sell |
| HENNESSY ADVISORS INC | 3,806,200 | 2,871,700 | -934,500 | 1.66 | 2.05 | +0.39 | sell |
| AMERICAN CENTURY COMPANIES INC | 1,927,261 | 2,802,649 | +875,388 | 0.02 | 0.03 | +0.02 | buy |
| MORGAN STANLEY | 1,015,315 | 2,734,527 | +1,719,212 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 795,368 | 2,193,985 | +1,398,617 | 0.02 | 0.07 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 1,077,809 | 2,117,936 | +1,040,127 | 0.00 | 0.01 | +0.00 | buy |
| General Catalyst Group Management, LLC | 2,107,719 | 2,107,719 | 0 | 3.11 | 1.05 | -2.06 | hold |
| CITADEL ADVISORS LLC | 1,480,225 | 2,007,797 | +527,572 | 0.02 | 0.04 | +0.02 | buy |
| Nuveen, LLC | 2,264,198 | 1,815,189 | -449,009 | 0.01 | 0.01 | +0.00 | sell |
| NORTHERN TRUST CORP | 1,922,219 | 1,765,215 | -157,004 | 0.00 | 0.01 | +0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,645,791 | 1,643,552 | -2,239 | 0.00 | 0.01 | +0.00 | sell |
| FARALLON CAPITAL MANAGEMENT LLC | 11,000 | 1,476,000 | +1,465,000 | 0.00 | 0.14 | +0.14 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 952,573 | 1,464,700 | +512,127 | 0.02 | 0.04 | +0.02 | buy |
| Clearbridge Investments, LLC | 1,457,783 | 1,449,224 | -8,559 | 0.02 | 0.03 | +0.01 | sell |
| Jump Financial, LLC | 160,474 | 1,441,506 | +1,281,032 | 0.03 | 0.40 | +0.37 | buy |
| TWO SIGMA INVESTMENTS, LP | 721,921 | 1,366,565 | +644,644 | 0.02 | 0.05 | +0.03 | buy |
| Dragoneer Investment Group, LLC | 6,917,448 | 1,346,154 | -5,571,294 | 1.91 | 0.59 | -1.32 | sell |
| Bienville Capital Management, LLC | 0 | 989,013 | +989,013 | 0.00 | 4.18 | +4.18 | buy |
| UBS Group AG | 1,065,649 | 985,634 | -80,015 | 0.00 | 0.00 | +0.00 | sell |
| BIT Capital GmbH | 4,521,445 | 961,119 | -3,560,326 | 7.14 | 1.34 | -5.80 | sell |
| D. E. Shaw & Co., Inc. | 295,491 | 910,698 | +615,207 | 0.00 | 0.02 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 501,972 | 884,289 | +382,317 | 0.03 | 0.07 | +0.04 | buy |
| SOUTHEASTERN ASSET MANAGEMENT INC/TN/ | 2,096,785 | 881,857 | -1,214,928 | 1.47 | 0.95 | -0.51 | sell |
| AMERIPRISE FINANCIAL INC | 1,303,527 | 869,679 | -433,848 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 553,299 | 823,832 | +270,533 | 0.00 | 0.00 | +0.00 | buy |
| BAILLIE GIFFORD & CO | 822,088 | 822,088 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Bank of New York Mellon Corp | 1,031,827 | 812,181 | -219,646 | 0.00 | 0.00 | +0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 285,997 | 794,389 | +508,392 | 0.00 | 0.01 | +0.01 | buy |
| PFM Health Sciences, LP | 860,821 | 735,033 | -125,788 | 0.87 | 1.37 | +0.50 | sell |
| Rock Springs Capital Management LP | 1,050,000 | 700,000 | -350,000 | 0.79 | 0.94 | +0.15 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,325,296 | 680,364 | -2,644,932 | 0.01 | 0.00 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 470,590 | 635,659 | +165,069 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 15,067 | 599,488 | +584,421 | 0.00 | 0.02 | +0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 595,882 | +595,882 | 0.00 | 0.10 | +0.10 | buy |
| RAYMOND JAMES FINANCIAL INC | 497,143 | 588,964 | +91,821 | 0.00 | 0.00 | +0.00 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 568,330 | 578,430 | +10,100 | 0.37 | 0.54 | +0.17 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,180,870 | 576,174 | -1,604,696 | 0.03 | 0.01 | -0.02 | sell |
| HRT FINANCIAL LP | 33,422 | 542,518 | +509,096 | 0.00 | 0.05 | +0.05 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 404,800 | 516,100 | +111,300 | 0.01 | 0.01 | +0.00 | buy |
| Sessa Capital IM, L.P. | 0 | 500,000 | +500,000 | 0.00 | 0.33 | +0.33 | buy |
| Quadrature Capital Ltd | 24,104 | 499,829 | +475,725 | 0.01 | 0.18 | +0.18 | buy |
| Alphabet Inc. | 481,988 | 481,988 | 0 | 0.40 | 0.48 | +0.08 | hold |
| Brevan Howard Capital Management LP | 45,291 | 465,218 | +419,927 | 0.02 | 0.11 | +0.09 | buy |
| Fiduciary Alliance LLC | 12,400 | 453,588 | +441,188 | 0.02 | 0.73 | +0.71 | buy |
| RBF Capital, LLC | 449,604 | 449,604 | 0 | 0.37 | 0.48 | +0.11 | hold |
| PDT Partners, LLC | 293,673 | 424,569 | +130,896 | 0.27 | 0.51 | +0.24 | buy |
| FMR LLC | 277,763 | 399,875 | +122,112 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 34,187 | 395,453 | +361,266 | 0.00 | 0.05 | +0.05 | buy |
| FRED ALGER MANAGEMENT, LLC | 574,536 | 372,345 | -202,191 | 0.04 | 0.04 | -0.01 | sell |
| BARCLAYS PLC | 272,993 | 369,158 | +96,165 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 238,200 | 356,800 | +118,600 | 0.01 | 0.02 | +0.01 | buy |
| IMC-Chicago, LLC | 156,370 | 348,714 | +192,344 | 0.08 | 0.19 | +0.11 | buy |
| TD ASSET MANAGEMENT INC | 673,232 | 332,490 | -340,742 | 0.01 | 0.01 | -0.00 | sell |
| Swiss National Bank | 328,200 | 328,200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rhenman & Partners Asset Management AB | 1,022,743 | 312,092 | -710,651 | 1.54 | 0.85 | -0.70 | sell |
| JANE STREET GROUP, LLC | 318,406 | 298,552 | -19,854 | 0.01 | 0.01 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 273,683 | 292,310 | +18,627 | 0.00 | 0.01 | +0.00 | buy |
| RHUMBLINE ADVISERS | 287,458 | 283,300 | -4,158 | 0.00 | 0.01 | +0.00 | sell |
| Skandinaviska Enskilda Banken AB (publ) | 178,000 | 281,500 | +103,500 | 0.01 | 0.03 | +0.01 | buy |
| GROUP ONE TRADING LLC | 103,945 | 281,415 | +177,470 | 0.06 | 0.20 | +0.14 | buy |
| General Equity Holdings LP | 270,000 | 270,000 | 0 | 3.21 | 4.38 | +1.17 | hold |
| Invesco Ltd. | 244,980 | 252,781 | +7,801 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 243,322 | 240,722 | -2,600 | 0.00 | 0.00 | +0.00 | sell |
| Walleye Trading LLC | 213,371 | 237,633 | +24,262 | 0.08 | 0.12 | +0.05 | buy |
| Trexquant Investment LP | 677,845 | 235,105 | -442,740 | 0.10 | 0.06 | -0.05 | sell |
| Y-Intercept (Hong Kong) Ltd | 0 | 234,153 | +234,153 | 0.00 | 0.12 | +0.12 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 203,924 | 231,671 | +27,747 | 0.01 | 0.02 | +0.01 | buy |
| STIFEL FINANCIAL CORP | 178,443 | 226,687 | +48,244 | 0.00 | 0.00 | +0.00 | buy |
| Lane Generational LLC | 0 | 223,886 | +223,886 | 0.00 | 4.48 | +4.48 | buy |
| JANUS HENDERSON GROUP PLC | 72,236 | 217,864 | +145,628 | 0.00 | 0.00 | +0.00 | buy |
| MAVERICK CAPITAL LTD | 0 | 213,095 | +213,095 | 0.00 | 0.07 | +0.07 | buy |
| Halter Ferguson Financial Inc. | 0 | 212,066 | +212,066 | 0.00 | 1.68 | +1.68 | buy |
| SIMPLEX TRADING, LLC | 0 | 210,776 | +210,776 | 0.00 | 0.12 | +0.12 | buy |
| Legal & General Group Plc | 191,939 | 204,275 | +12,336 | 0.00 | 0.00 | +0.00 | buy |
| SkyView Investment Advisors, LLC | 188,353 | 190,539 | +2,186 | 0.37 | 0.56 | +0.19 | buy |
| Graham Capital Management, L.P. | 194,902 | 190,267 | -4,635 | 0.08 | 0.12 | +0.04 | sell |
| AQR CAPITAL MANAGEMENT LLC | 203,134 | 190,051 | -13,083 | 0.00 | 0.00 | +0.00 | sell |
| OSAIC HOLDINGS, INC. | 48,492 | 186,997 | +138,505 | 0.00 | 0.01 | +0.01 | buy |
| 12 West Capital Management LP | 186,855 | 186,855 | 0 | 0.36 | 0.42 | +0.06 | hold |
| NewEdge Advisors, LLC | 188,058 | 184,373 | -3,685 | 0.01 | 0.02 | +0.01 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 215,650 | 183,396 | -32,254 | 0.01 | 0.01 | +0.00 | sell |
| Lingotto Investment Management LLP | 379,116 | 180,000 | -199,116 | 0.13 | 0.08 | -0.05 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 154,254 | 179,214 | +24,960 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 14,920 | 178,795 | +163,875 | 0.00 | 0.00 | +0.00 | buy |
| IVY LANE CAPITAL MANAGEMENT, LLC | 125,000 | 175,000 | +50,000 | 0.99 | 2.07 | +1.08 | buy |
| Venture Visionary Partners LLC | 0 | 164,176 | +164,176 | 0.00 | 0.13 | +0.13 | buy |
| CITIGROUP INC | 158,751 | 158,867 | +116 | 0.00 | 0.00 | +0.00 | buy |
| Fortis Group Advisors, LLC | 0 | 156,622 | +156,622 | 0.00 | 0.40 | +0.40 | buy |
| ALGERT GLOBAL LLC | 78,692 | 154,808 | +76,116 | 0.03 | 0.07 | +0.04 | buy |