| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 11,553,759 | 7,622,935 | -3,930,824 | 0.02 | 0.02 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 7,023,689 | 6,514,952 | -508,737 | 0.08 | 0.10 | +0.02 | sell |
| FMR LLC | 4,116,081 | 5,488,272 | +1,372,191 | 0.02 | 0.04 | +0.02 | buy |
| RATIONAL ADVISORS, INC. | 2,049,000 | 5,429,000 | +3,380,000 | 0.21 | 0.62 | +0.40 | buy |
| Invesco Ltd. | 4,946,469 | 4,429,755 | -516,714 | 0.06 | 0.05 | -0.01 | sell |
| GOLDMAN SACHS GROUP INC | 4,435,839 | 3,775,895 | -659,944 | 0.05 | 0.06 | +0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 4,229,531 | 3,719,301 | -510,230 | 0.32 | 0.42 | +0.10 | sell |
| Capital International Investors | 3,481,318 | 3,399,604 | -81,714 | 0.08 | 0.11 | +0.03 | sell |
| Deep Track Capital, LP | 3,338,241 | 3,393,312 | +55,071 | 6.36 | 7.50 | +1.14 | buy |
| FRANKLIN RESOURCES INC | 3,448,193 | 3,236,065 | -212,128 | 0.08 | 0.11 | +0.03 | sell |
| AMERIPRISE FINANCIAL INC | 1,414,886 | 3,150,897 | +1,736,011 | 0.03 | 0.10 | +0.07 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 2,550,314 | 2,629,007 | +78,693 | 0.79 | 1.07 | +0.28 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,508,883 | 2,521,596 | -987,287 | 0.02 | 0.02 | +0.00 | sell |
| BAILLIE GIFFORD & CO | 3,859,046 | 2,284,127 | -1,574,919 | 0.36 | 0.31 | -0.05 | sell |
| STATE STREET CORP | 2,884,620 | 2,263,504 | -621,116 | 0.01 | 0.01 | +0.00 | sell |
| FEDERATED HERMES, INC. | 1,887,584 | 1,999,178 | +111,594 | 0.28 | 0.43 | +0.15 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 2,362,379 | 1,957,828 | -404,551 | 3.61 | 3.93 | +0.32 | sell |
| LORD, ABBETT & CO. LLC | 1,899,113 | 1,813,491 | -85,622 | 0.57 | 0.78 | +0.21 | sell |
| JANE STREET GROUP, LLC | 4,803 | 1,783,444 | +1,778,641 | 0.00 | 0.17 | +0.17 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1,362,539 | 1,624,459 | +261,920 | 0.53 | 0.80 | +0.27 | buy |
| MILLENNIUM MANAGEMENT LLC | 921,395 | 1,622,458 | +701,063 | 0.06 | 0.16 | +0.10 | buy |
| NORGES BANK | 0 | 1,548,518 | +1,548,518 | 0.00 | 0.02 | +0.02 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,524,282 | 1,533,985 | +9,703 | 1.03 | 1.33 | +0.30 | buy |
| RTW INVESTMENTS, LP | 1,481,033 | 1,481,033 | 0 | 1.36 | 1.90 | +0.54 | hold |
| Artisan Partners Limited Partnership | 814,571 | 1,478,928 | +664,357 | 0.12 | 0.36 | +0.24 | buy |
| CITADEL ADVISORS LLC | 775,941 | 1,449,534 | +673,593 | 0.05 | 0.12 | +0.07 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,623,511 | 1,439,787 | -183,724 | 0.03 | 0.04 | +0.01 | sell |
| Hood River Capital Management LLC | 1,310,065 | 1,395,307 | +85,242 | 1.21 | 1.52 | +0.30 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,905,637 | 1,395,240 | -510,397 | 0.06 | 0.04 | -0.02 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,205,701 | 1,390,337 | +184,636 | 0.10 | 0.16 | +0.07 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 951,114 | 1,311,320 | +360,206 | 0.29 | 0.59 | +0.30 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 1,268,587 | +1,268,587 | 0.00 | 0.03 | +0.03 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,451,803 | 1,268,587 | -183,216 | 0.02 | 0.03 | +0.00 | sell |
| D. E. Shaw & Co., Inc. | 427,475 | 1,255,658 | +828,183 | 0.03 | 0.12 | +0.09 | buy |
| MORGAN STANLEY | 1,487,324 | 1,088,477 | -398,847 | 0.01 | 0.01 | +0.00 | sell |
| Temasek Holdings (Private) Ltd | 985,571 | 1,023,927 | +38,356 | 0.31 | 0.42 | +0.11 | buy |
| Bank of New York Mellon Corp | 1,391,187 | 994,688 | -396,499 | 0.02 | 0.02 | +0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 895,221 | 976,793 | +81,572 | 0.01 | 0.01 | +0.00 | buy |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 862,915 | 967,697 | +104,782 | 3.69 | 3.77 | +0.08 | buy |
| Point72 Asset Management, L.P. | 695,940 | 920,807 | +224,867 | 0.11 | 0.21 | +0.10 | buy |
| UBS Group AG | 1,405,837 | 866,046 | -539,791 | 0.02 | 0.02 | -0.00 | sell |
| CADIAN CAPITAL MANAGEMENT, LP | 779,648 | 757,393 | -22,255 | 8.77 | 8.60 | -0.17 | sell |
| NORTHERN TRUST CORP | 1,112,439 | 743,769 | -368,670 | 0.01 | 0.01 | -0.00 | sell |
| HRT FINANCIAL LP | 0 | 703,915 | +703,915 | 0.00 | 0.19 | +0.19 | buy |
| Alyeska Investment Group, L.P. | 1,489,566 | 647,818 | -841,748 | 0.39 | 0.25 | -0.14 | sell |
| Allspring Global Investments Holdings, LLC | 608,826 | 646,509 | +37,683 | 0.09 | 0.17 | +0.08 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 75,989 | 644,138 | +568,149 | 0.01 | 0.09 | +0.08 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 972,563 | 621,500 | -351,063 | 0.02 | 0.02 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 867,537 | 608,695 | -258,842 | 0.04 | 0.04 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 435,200 | 583,700 | +148,500 | 0.88 | 1.66 | +0.78 | buy |
| Squarepoint Ops LLC | 191,740 | 580,133 | +388,393 | 0.04 | 0.17 | +0.13 | buy |
| Erste Asset Management GmbH | 815,917 | 577,313 | -238,604 | 0.65 | 0.69 | +0.04 | sell |
| SAMLYN CAPITAL, LLC | 249,137 | 561,876 | +312,739 | 0.40 | 1.40 | +1.00 | buy |
| JPMORGAN CHASE & CO | 304,317 | 549,088 | +244,771 | 0.00 | 0.00 | +0.00 | buy |
| ARK Investment Management LLC | 486,675 | 506,416 | +19,741 | 0.35 | 0.49 | +0.14 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 505,034 | 480,839 | -24,195 | 0.05 | 0.06 | +0.01 | sell |
| BROWN ADVISORY INC | 329,564 | 445,558 | +115,994 | 0.05 | 0.10 | +0.05 | buy |
| Aristotle Atlantic Partners, LLC | 445,530 | 442,816 | -2,714 | 1.93 | 2.75 | +0.83 | sell |
| First Light Asset Management, LLC | 280,299 | 441,586 | +161,287 | 2.32 | 4.03 | +1.71 | buy |
| FRED ALGER MANAGEMENT, LLC | 622,259 | 416,566 | -205,693 | 0.25 | 0.21 | -0.04 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 483,767 | 404,816 | -78,951 | 0.03 | 0.03 | +0.01 | sell |
| Nikko Asset Management Americas, Inc. | 483,557 | 403,817 | -79,740 | 0.63 | 0.78 | +0.15 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 393,836 | 391,974 | -1,862 | 0.02 | 0.03 | +0.01 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 816,095 | 371,763 | -444,332 | 0.12 | 0.08 | -0.04 | sell |
| 1832 Asset Management L.P. | 0 | 369,000 | +369,000 | 0.00 | 0.07 | +0.07 | buy |
| EMERALD ADVISERS, LLC | 841,917 | 364,022 | -477,895 | 2.46 | 1.29 | -1.18 | sell |
| JENNISON ASSOCIATES LLC | 203,778 | 356,001 | +152,223 | 0.01 | 0.03 | +0.02 | buy |
| SEI INVESTMENTS CO | 341,013 | 346,438 | +5,425 | 0.03 | 0.05 | +0.02 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 0 | 341,574 | +341,574 | 0.00 | 0.02 | +0.02 | buy |
| RAYMOND JAMES FINANCIAL INC | 338,389 | 337,197 | -1,192 | 0.01 | 0.01 | +0.00 | sell |
| FARALLON CAPITAL MANAGEMENT LLC | 8,000 | 322,200 | +314,200 | 0.00 | 0.28 | +0.28 | buy |
| Handelsbanken Fonder AB | 115,841 | 301,041 | +185,200 | 0.04 | 0.13 | +0.09 | buy |
| Eagle Health Investments LP | 310,281 | 300,685 | -9,596 | 6.02 | 7.48 | +1.46 | sell |
| Nuveen, LLC | 438,357 | 289,325 | -149,032 | 0.01 | 0.01 | -0.00 | sell |
| Clearbridge Investments, LLC | 0 | 280,294 | +280,294 | 0.00 | 0.03 | +0.03 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 238,462 | 274,052 | +35,590 | 0.01 | 0.01 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 149,615 | 272,671 | +123,056 | 0.02 | 0.05 | +0.03 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 519,545 | 271,380 | -248,165 | 2.33 | 1.43 | -0.90 | sell |
| ROYAL BANK OF CANADA | 146,404 | 264,263 | +117,859 | 0.00 | 0.01 | +0.00 | buy |
| Stephens Investment Management Group LLC | 0 | 254,310 | +254,310 | 0.00 | 0.41 | +0.41 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 244,051 | 250,012 | +5,961 | 0.04 | 0.06 | +0.02 | buy |
| Swiss National Bank | 222,100 | 243,500 | +21,400 | 0.01 | 0.02 | +0.01 | buy |
| SEGALL BRYANT & HAMILL, LLC | 232,222 | 236,340 | +4,118 | 0.22 | 0.42 | +0.20 | buy |
| RHUMBLINE ADVISERS | 157,909 | 231,600 | +73,691 | 0.01 | 0.03 | +0.01 | buy |
| Sicart Associates LLC | 230,103 | 231,015 | +912 | 5.46 | 8.49 | +3.03 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 0 | 230,000 | +230,000 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 215,468 | 228,884 | +13,416 | 0.01 | 0.02 | +0.01 | buy |
| Northwest & Ethical Investments L.P. | 0 | 225,000 | +225,000 | 0.00 | 0.01 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 254,788 | 215,395 | -39,393 | 0.05 | 0.06 | +0.01 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 806 | 210,541 | +209,735 | 0.00 | 0.02 | +0.02 | buy |
| Russell Investments Group, Ltd. | 188,140 | 208,875 | +20,735 | 0.02 | 0.03 | +0.01 | buy |
| Science & Technology Partners, L.P. | 0 | 208,817 | +208,817 | 0.00 | 5.28 | +5.28 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 26,967 | 200,672 | +173,705 | 0.18 | 1.60 | +1.42 | buy |
| Bank of New York Mellon Corp | 200,000 | 200,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TREMBLANT CAPITAL GROUP | 0 | 197,795 | +197,795 | 0.00 | 0.85 | +0.85 | buy |
| PICTON MAHONEY ASSET MANAGEMENT | 249,991 | 191,876 | -58,115 | 0.24 | 0.27 | +0.02 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 184,846 | 185,430 | +584 | 0.01 | 0.01 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 185,150 | +185,150 | 0.00 | 0.02 | +0.02 | buy |
| Casdin Capital, LLC | 315,000 | 185,000 | -130,000 | 2.20 | 1.39 | -0.81 | sell |
| Atika Capital Management LLC | 91,000 | 181,000 | +90,000 | 1.33 | 2.69 | +1.37 | buy |