| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANE STREET GROUP, LLC | 16,788 | 604,620 | +587,832 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 2,838,765 | 3,358,809 | +520,044 | 0.01 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 177,779 | 499,794 | +322,015 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 246,895 | +246,895 | 0.00 | 0.09 | +0.09 | buy |
| Man Group plc | 0 | 144,630 | +144,630 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 138,029 | +138,029 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 131,116 | +131,116 | 0.00 | 0.00 | +0.00 | buy |
| Alyeska Investment Group, L.P. | 613,822 | 733,203 | +119,381 | 0.02 | 0.02 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 132,351 | 244,416 | +112,065 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 20,088 | 129,700 | +109,612 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 38,498 | 147,811 | +109,313 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 104,369 | +104,369 | 0.00 | 0.00 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 499,814 | 603,497 | +103,683 | 0.38 | 0.33 | -0.05 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 91,496 | +91,496 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 78,431 | +78,431 | 0.00 | 0.03 | +0.03 | buy |
| Jump Financial, LLC | 33,900 | 103,000 | +69,100 | 0.01 | 0.01 | +0.01 | buy |
| Qube Research & Technologies Ltd | 26,113 | 88,626 | +62,513 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 57,299 | 114,732 | +57,433 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 52,829 | +52,829 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 525,000 | 564,400 | +39,400 | 0.02 | 0.02 | -0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 33,945 | +33,945 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 33,905 | +33,905 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 32,256 | +32,256 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 29,100 | +29,100 | 0.00 | 0.01 | +0.01 | buy |
| Tower Research Capital LLC (TRC) | 2,128 | 29,089 | +26,961 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 59,778 | 85,078 | +25,300 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 22,425 | 47,347 | +24,922 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 23,787 | +23,787 | 0.00 | 0.01 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 61,185 | 82,182 | +20,997 | 0.01 | 0.01 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 20,578 | +20,578 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 19,348 | +19,348 | 0.00 | 0.01 | +0.01 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 16,929 | +16,929 | 0.00 | 0.01 | +0.01 | buy |
| STIFEL FINANCIAL CORP | 0 | 16,150 | +16,150 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 13,816 | 24,728 | +10,912 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 11,448 | 21,422 | +9,974 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 7,543 | +7,543 | 0.00 | 0.00 | +0.00 | buy |
| Chicago Partners Investment Group LLC | 13,579 | 18,315 | +4,736 | 0.00 | 0.00 | +0.00 | buy |
| Global Retirement Partners, LLC | 0 | 2,000 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 13,600 | 14,600 | +1,000 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 56,190 | 56,678 | +488 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 264,603 | 264,603 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 14,932,063 | 14,932,063 | 0 | 1.22 | 0.90 | -0.32 | hold |
| Laurion Capital Management LP | 1,895,023 | 1,895,023 | 0 | 0.21 | 0.26 | +0.06 | hold |
| Intrepid Financial Planning Group LLC | 30,150 | 30,150 | 0 | 0.06 | 0.06 | -0.01 | hold |
| Caption Management, LLC | 40,000 | 40,000 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Ikarian Capital, LLC | 315,265 | 315,265 | 0 | 0.49 | 0.33 | -0.15 | hold |
| Sands Capital Alternatives, LLC | 3,417,075 | 3,417,075 | 0 | 4.20 | 3.65 | -0.54 | hold |
| CATALYST FINANCIAL PARTNERS LLC | 89,699 | 89,699 | 0 | 0.12 | 0.10 | -0.02 | hold |
| Knollwood Investment Advisory, LLC | 1,628,510 | 1,628,510 | 0 | 3.16 | 1.30 | -1.86 | hold |
| Kelly Financial Services LLC | 944 | 944 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Daiwa Securities Group Inc. | 165 | 0 | -165 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 657 | 0 | -657 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 1,481 | 0 | -1,481 | 0.00 | 0.00 | -0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,393 | 413 | -2,980 | 0.00 | 0.00 | -0.00 | sell |
| LMR Partners LLP | 14,663 | 0 | -14,663 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 16,538 | 0 | -16,538 | 0.01 | 0.00 | -0.01 | sell |
| VANGUARD GROUP INC | 1,856,552 | 1,839,552 | -17,000 | 0.00 | 0.00 | -0.00 | sell |
| Pinnacle Wealth Management Advisory Group, LLC | 18,020 | 0 | -18,020 | 0.01 | 0.00 | -0.01 | sell |
| PINNACLE ASSOCIATES LTD | 18,020 | 0 | -18,020 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 75,602 | 55,791 | -19,811 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 23,500 | 0 | -23,500 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 25,492 | 0 | -25,492 | 0.00 | 0.00 | -0.00 | sell |
| DekaBank Deutsche Girozentrale | 40,000 | 0 | -40,000 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 69,538 | 0 | -69,538 | 0.01 | 0.00 | -0.01 | sell |
| Schonfeld Strategic Advisors LLC | 645,112 | 561,542 | -83,570 | 0.02 | 0.02 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 87,400 | 0 | -87,400 | 0.00 | 0.00 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 104,359 | 0 | -104,359 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 115,033 | 0 | -115,033 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 1,716,290 | 1,495,284 | -221,006 | 0.01 | 0.01 | -0.00 | sell |
| Rock Springs Capital Management LP | 2,812,579 | 2,300,059 | -512,520 | 0.31 | 0.22 | -0.09 | sell |
| Altium Capital Management LLC | 650,000 | 0 | -650,000 | 1.56 | 0.00 | -1.56 | sell |
| GREAT POINT PARTNERS LLC | 1,074,101 | 0 | -1,074,101 | 0.84 | 0.00 | -0.84 | sell |
| Deep Track Capital, LP | 2,513,044 | 0 | -2,513,044 | 0.40 | 0.00 | -0.40 | sell |