| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 459,111 | 782,844 | +323,733 | 0.89 | 1.51 | +0.62 | buy |
| VANGUARD GROUP INC | 3,742,002 | 3,995,345 | +253,343 | 0.01 | 0.01 | +0.00 | buy |
| Iron Triangle Partners LP | 0 | 252,266 | +252,266 | 0.00 | 3.19 | +3.19 | buy |
| FMR LLC | 902,136 | 1,088,087 | +185,951 | 0.00 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 45,315 | 197,935 | +152,620 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 3,785 | 137,064 | +133,279 | 0.00 | 0.01 | +0.01 | buy |
| Cutter Capital Management, LP | 0 | 105,767 | +105,767 | 0.00 | 2.81 | +2.81 | buy |
| BVF INC/IL | 955,000 | 1,046,000 | +91,000 | 2.15 | 2.75 | +0.60 | buy |
| MORGAN STANLEY | 321,981 | 410,150 | +88,169 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 85,932 | +85,932 | 0.00 | 0.01 | +0.01 | buy |
| Hood River Capital Management LLC | 549,066 | 625,084 | +76,018 | 0.92 | 0.91 | -0.01 | buy |
| Sofinnova Investments, Inc. | 310,198 | 379,527 | +69,329 | 1.57 | 2.82 | +1.25 | buy |
| Invesco Ltd. | 557,861 | 625,179 | +67,318 | 0.01 | 0.01 | +0.00 | buy |
| Point72 Asset Management, L.P. | 479,044 | 542,620 | +63,576 | 0.12 | 0.17 | +0.05 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 62,167 | +62,167 | 0.00 | 0.01 | +0.01 | buy |
| FRANKLIN RESOURCES INC | 108,838 | 160,534 | +51,696 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 50,141 | +50,141 | 0.00 | 0.18 | +0.18 | buy |
| IFP Advisors, Inc | 0 | 49,801 | +49,801 | 0.00 | 0.16 | +0.16 | buy |
| BARCLAYS PLC | 16,276 | 61,785 | +45,509 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 30,370 | +30,370 | 0.00 | 0.00 | +0.00 | buy |
| LOOMIS SAYLES & CO L P | 269,089 | 298,586 | +29,497 | 0.03 | 0.04 | +0.01 | buy |
| ExodusPoint Capital Management, LP | 0 | 29,479 | +29,479 | 0.00 | 0.03 | +0.03 | buy |
| JPMORGAN CHASE & CO | 184,576 | 212,110 | +27,534 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 0 | 27,231 | +27,231 | 0.00 | 0.01 | +0.01 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 96,027 | 120,540 | +24,513 | 0.08 | 0.10 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 884,895 | 908,459 | +23,564 | 0.01 | 0.01 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 58,909 | 81,997 | +23,088 | 0.04 | 0.06 | +0.02 | buy |
| CITIGROUP INC | 16,798 | 35,619 | +18,821 | 0.00 | 0.00 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 26,591 | 43,092 | +16,501 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 12,836 | 27,162 | +14,326 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 14,050 | +14,050 | 0.00 | 0.03 | +0.03 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 309,818 | 322,596 | +12,778 | 0.00 | 0.01 | +0.00 | buy |
| PDT Partners, LLC | 0 | 11,701 | +11,701 | 0.00 | 0.09 | +0.09 | buy |
| SG Americas Securities, LLC | 0 | 11,553 | +11,553 | 0.00 | 0.00 | +0.00 | buy |
| FORA Capital, LLC | 0 | 11,058 | +11,058 | 0.00 | 0.12 | +0.12 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 10,941 | +10,941 | 0.00 | 0.01 | +0.01 | buy |
| Mariner, LLC | 3,137 | 13,286 | +10,149 | 0.00 | 0.00 | +0.00 | buy |
| Nicholas Investment Partners, LP | 0 | 10,135 | +10,135 | 0.00 | 0.08 | +0.08 | buy |
| Baird Financial Group, Inc. | 0 | 10,118 | +10,118 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.10 | +0.10 | buy |
| Brevan Howard Capital Management LP | 4,782 | 14,355 | +9,573 | 0.03 | 0.06 | +0.04 | buy |
| ROYCE & ASSOCIATES LP | 13,000 | 22,500 | +9,500 | 0.01 | 0.02 | +0.01 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 9,466 | +9,466 | 0.00 | 0.00 | +0.00 | buy |
| Versor Investments LP | 0 | 8,807 | +8,807 | 0.00 | 0.13 | +0.13 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 734,620 | 742,745 | +8,125 | 0.01 | 0.01 | +0.00 | buy |
| NORTHERN TRUST CORP | 324,493 | 332,582 | +8,089 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 39,704 | 47,762 | +8,058 | 0.00 | 0.00 | +0.00 | buy |
| Atika Capital Management LLC | 49,000 | 57,000 | +8,000 | 0.46 | 0.55 | +0.09 | buy |
| Altium Capital Management LLC | 50,000 | 58,000 | +8,000 | 1.66 | 1.55 | -0.11 | buy |
| Cynosure Group, LLC | 0 | 7,930 | +7,930 | 0.00 | 0.10 | +0.10 | buy |
| SEI INVESTMENTS CO | 40,624 | 48,361 | +7,737 | 0.00 | 0.01 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 80,203 | 87,758 | +7,555 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 106,767 | 114,236 | +7,469 | 0.01 | 0.01 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 8,620 | 15,656 | +7,036 | 0.02 | 0.05 | +0.03 | buy |
| TUDOR INVESTMENT CORP ET AL | 18,983 | 25,832 | +6,849 | 0.02 | 0.03 | +0.01 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 6,513 | +6,513 | 0.00 | 0.06 | +0.06 | buy |
| Values First Advisors, Inc. | 0 | 6,322 | +6,322 | 0.00 | 0.31 | +0.31 | buy |
| Privium Fund Management B.V. | 74,332 | 80,232 | +5,900 | 1.50 | 1.79 | +0.30 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 7,996 | 13,733 | +5,737 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 5,722 | +5,722 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 74,767 | 80,014 | +5,247 | 0.00 | 0.01 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 5,197 | +5,197 | 0.00 | 0.01 | +0.01 | buy |
| EntryPoint Capital, LLC | 171 | 5,156 | +4,985 | 0.01 | 0.26 | +0.26 | buy |
| GREAT LAKES ADVISORS, LLC | 12,141 | 16,728 | +4,587 | 0.01 | 0.01 | +0.00 | buy |
| Point72 Europe (London) LLP | 30,741 | 34,570 | +3,829 | 0.21 | 0.26 | +0.05 | buy |
| Cerity Partners LLC | 0 | 3,743 | +3,743 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 5,580 | 9,232 | +3,652 | 0.06 | 0.09 | +0.03 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 3,400 | +3,400 | 0.00 | 0.00 | +0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 0 | 3,348 | +3,348 | 0.00 | 0.07 | +0.07 | buy |
| COMERICA BANK | 7,979 | 10,944 | +2,965 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 91,804 | 94,483 | +2,679 | 0.01 | 0.01 | +0.00 | buy |
| Whalen Wealth Management Inc. | 0 | 2,628 | +2,628 | 0.00 | 0.17 | +0.17 | buy |
| Creative Planning | 8,365 | 10,854 | +2,489 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 2,408 | +2,408 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 0 | 2,382 | +2,382 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 2,339 | +2,339 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 0 | 2,327 | +2,327 | 0.00 | 0.01 | +0.01 | buy |
| Moors & Cabot, Inc. | 0 | 2,230 | +2,230 | 0.00 | 0.01 | +0.01 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 17,897 | 19,935 | +2,038 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 7,707 | 9,722 | +2,015 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 10,300 | 12,300 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 23,358 | 25,358 | +2,000 | 0.00 | 0.01 | +0.00 | buy |
| STRS OHIO | 2,800 | 4,600 | +1,800 | 0.00 | 0.00 | +0.00 | buy |
| Janney Montgomery Scott LLC | 5,630 | 7,199 | +1,569 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 14,881 | 16,372 | +1,491 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 6,770 | 7,742 | +972 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 19,054 | 19,808 | +754 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 27,175 | 27,862 | +687 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 33,649 | 34,263 | +614 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 15,118 | 15,666 | +548 | 0.03 | 0.03 | +0.00 | buy |
| US BANCORP \DE\ | 132,705 | 133,126 | +421 | 0.01 | 0.02 | +0.00 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 113,345 | 113,692 | +347 | 0.02 | 0.02 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,418 | 1,736 | +318 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 300 | 600 | +300 | 0.00 | 0.01 | +0.00 | buy |
| Arizona State Retirement System | 8,630 | 8,890 | +260 | 0.00 | 0.01 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 144 | 279 | +135 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 5,081 | 5,178 | +97 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 0 | 82 | +82 | 0.00 | 0.00 | +0.00 | buy |
| Pathstone Holdings, LLC | 3,767 | 3,843 | +76 | 0.00 | 0.00 | +0.00 | buy |
| TORRAY INVESTMENT PARTNERS LLC | 11,747 | 11,823 | +76 | 0.14 | 0.15 | +0.01 | buy |