| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,037,448 | 1,509,870 | +472,422 | 0.01 | 0.03 | +0.02 | buy |
| Deep Track Capital, LP | 900,000 | 1,150,000 | +250,000 | 3.05 | 4.79 | +1.74 | buy |
| Voleon Capital Management LP | 16,734 | 110,179 | +93,445 | 0.05 | 0.43 | +0.38 | buy |
| Vestal Point Capital, LP | 150,000 | 210,000 | +60,000 | 0.83 | 1.41 | +0.58 | buy |
| First Turn Management, LLC | 152,614 | 206,921 | +54,307 | 2.78 | 4.32 | +1.54 | buy |
| Nicholas Investment Partners, LP | 48,657 | 91,564 | +42,907 | 0.45 | 1.22 | +0.77 | buy |
| Edgestream Partners, L.P. | 18,346 | 56,364 | +38,018 | 0.07 | 0.29 | +0.22 | buy |
| ROYCE & ASSOCIATES LP | 56,036 | 94,017 | +37,981 | 0.07 | 0.17 | +0.11 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 126,382 | 157,691 | +31,309 | 0.14 | 0.31 | +0.17 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 209,069 | 188,258 | +20,811 | 0.08 | 0.09 | +0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 150,000 | 170,000 | +20,000 | 0.03 | 0.05 | +0.03 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 317 | 17,381 | +17,064 | 0.01 | 0.48 | +0.48 | buy |
| AXIOM INVESTORS LLC /DE | 49,253 | 63,390 | +14,137 | 0.04 | 0.10 | +0.06 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 997,700 | 1,010,249 | +12,549 | 0.01 | 0.01 | 0.00 | buy |
| CASTLEARK MANAGEMENT LLC | 15,143 | 24,253 | +9,110 | 0.05 | 0.13 | +0.08 | buy |
| Y-Intercept (Hong Kong) Ltd | 27,027 | 34,854 | +7,827 | 0.08 | 0.15 | 0.00 | buy |
| Atika Capital Management LLC | 49,000 | 55,500 | +6,500 | 0.48 | 1.07 | +0.59 | buy |
| Hood River Capital Management LLC | 359,957 | 366,176 | +6,219 | 0.52 | 0.73 | +0.22 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 368,434 | 363,114 | +5,320 | 0.02 | 0.04 | 0.00 | sell |
| Legato Capital Management LLC | 5,051 | 9,627 | +4,576 | 0.07 | 0.15 | +0.08 | buy |
| Pallas Capital Advisors LLC | 39,444 | 43,909 | +4,465 | 0.18 | 0.26 | +0.09 | buy |
| GSA CAPITAL PARTNERS LLP | 4,767 | 9,117 | +4,350 | 0.05 | 0.16 | 0.00 | buy |
| Privium Fund Management B.V. | 52,732 | 56,878 | +4,146 | 1.15 | 1.91 | +0.76 | buy |
| Baader Bank Aktiengesellschaft | 2,115 | 5,823 | +3,708 | 0.02 | 0.07 | +0.06 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 3,800 | 7,406 | +3,606 | 0.01 | 0.03 | +0.02 | buy |
| Aberdeen Group plc | 94,648 | 97,413 | +2,765 | 0.02 | 0.03 | +0.01 | buy |
| Headlands Technologies LLC | 2,574 | 5,187 | +2,613 | 0.02 | 0.08 | +0.05 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 65,505 | 67,608 | +2,103 | 0.41 | 0.60 | +0.19 | buy |
| HighVista Strategies LLC | 9,348 | 11,131 | +1,783 | 0.28 | 0.52 | +0.25 | buy |
| F/m Investments LLC | 39,495 | 41,132 | +1,637 | 0.18 | 0.29 | +0.10 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 16,049 | 14,428 | +1,621 | 0.02 | 0.02 | +0.01 | sell |
| ProShare Advisors LLC | 8,698 | 9,730 | +1,032 | 0.00 | 0.00 | 0.00 | buy |
| SECTORAL ASSET MANAGEMENT INC | 1,020 | 1,740 | +720 | 0.08 | 0.25 | +0.18 | buy |
| PROFUND ADVISORS LLC | 3,122 | 2,468 | +654 | 0.01 | 0.01 | 0.00 | sell |
| Quantitative Investment Management, LLC | 2,095 | 2,524 | +429 | 0.04 | 0.04 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 4,183 | 4,611 | +428 | 0.15 | 0.23 | +0.08 | buy |
| Stanley-Laman Group, Ltd. | 17,501 | 17,918 | +417 | 0.30 | 0.42 | +0.11 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 38,774 | 39,134 | +360 | 0.10 | 0.15 | +0.05 | buy |
| INTRUST BANK NA | 3,764 | 4,052 | +288 | 0.04 | 0.06 | +0.02 | buy |
| GREAT LAKES ADVISORS, LLC | 6,676 | 6,765 | +89 | 0.01 | 0.01 | +0.00 | buy |
| McAdam, LLC | 2,198 | 2,274 | +76 | 0.01 | 0.02 | +0.01 | buy |
| Birchview Capital, LP | 6,000 | 6,061 | +61 | 0.55 | 0.65 | +0.10 | buy |
| Moors & Cabot, Inc. | 2,380 | 2,430 | +50 | 0.01 | 0.02 | +0.01 | buy |
| Cannell & Spears LLC | 84,151 | 84,154 | +3 | 0.19 | 0.29 | +0.09 | buy |
| MEEDER ASSET MANAGEMENT INC | 28 | 30 | +2 | 0.00 | 0.00 | +0.00 | buy |
| Rakuten Securities, Inc. | 30 | 10 | -20 | 0.00 | 0.00 | -0.00 | sell |
| GF FUND MANAGEMENT CO. LTD. | 1,074 | 990 | -84 | 0.00 | 0.00 | +0.00 | sell |
| NBC SECURITIES, INC. | 2,670 | 2,435 | -235 | 0.03 | 0.03 | +0.01 | sell |
| Tortoise Investment Management, LLC | 2,136 | 1,870 | -266 | 0.02 | 0.03 | +0.01 | sell |
| OAK RIDGE INVESTMENTS LLC | 12,065 | 11,741 | -324 | 0.09 | 0.13 | +0.04 | sell |
| FIDUCIARY FAMILY OFFICE, LLC | 2,670 | 2,283 | -387 | 0.09 | 0.12 | +0.03 | sell |
| Meridian Wealth Management, LLC | 22,124 | 21,724 | -400 | 0.10 | 0.14 | +0.04 | sell |
| Dana Investment Advisors, Inc. | 33,612 | 33,197 | -415 | 0.12 | 0.18 | +0.06 | sell |
| Values First Advisors, Inc. | 4,882 | 4,402 | -480 | 0.32 | 0.42 | +0.10 | sell |
| China Universal Asset Management Co., Ltd. | 8,747 | 8,215 | -532 | 0.09 | 0.12 | +0.03 | sell |
| Bayforest Capital Ltd | 1,062 | 478 | -584 | 0.06 | 0.07 | +0.00 | sell |
| Knights of Columbus Asset Advisors LLC | 20,426 | 19,806 | -620 | 0.14 | 0.21 | +0.06 | sell |
| Old North State Wealth Management, LLC | 3,450 | 2,800 | -650 | 0.20 | 0.24 | +0.04 | sell |
| EMERALD ADVISERS, LLC | 108,942 | 108,082 | -860 | 0.42 | 0.61 | +0.18 | sell |
| DnB Asset Management AS | 101,981 | 101,102 | -879 | 0.05 | 0.06 | +0.02 | sell |
| STRS OHIO | 11,900 | 10,800 | -1,100 | 0.01 | 0.01 | +0.00 | sell |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | 5,650 | 4,400 | -1,250 | 0.01 | 0.01 | +0.00 | sell |
| J. Safra Sarasin Holding AG | 8,897 | 7,383 | -1,514 | 0.02 | 0.02 | +0.00 | sell |
| ALETHEA CAPITAL MANAGEMENT, LLC | 670,883 | 668,710 | -2,173 | 52.34 | 59.30 | +6.96 | sell |
| TD ASSET MANAGEMENT INC | 44,192 | 41,972 | -2,220 | 0.00 | 0.01 | +0.00 | sell |
| CIBC WORLD MARKETS CORP | 4,987 | 2,715 | -2,272 | 0.00 | 0.00 | -0.00 | sell |
| TORRAY INVESTMENT PARTNERS LLC | 17,419 | 14,794 | -2,625 | 0.29 | 0.39 | +0.10 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 223,408 | 220,518 | -2,890 | 0.19 | 0.27 | +0.08 | sell |
| Granite Investment Partners, LLC | 88,558 | 84,894 | -3,664 | 0.61 | 0.92 | +0.31 | sell |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 19,288 | 15,305 | -3,983 | 0.15 | 0.19 | +0.04 | sell |
| Cynosure Group, LLC | 7,844 | 3,475 | -4,369 | 0.10 | 0.06 | -0.04 | sell |
| WESBANCO BANK INC | 13,300 | 8,800 | -4,500 | 0.04 | 0.04 | -0.00 | sell |
| INCEPTIONR LLC | 8,659 | 3,934 | -4,725 | 0.25 | 0.20 | -0.05 | sell |
| Perbak Capital Partners LLP | 6,313 | 1,202 | -5,111 | 0.13 | 0.07 | -0.07 | sell |
| WCM INVESTMENT MANAGEMENT, LLC | 119,696 | 112,058 | -7,638 | 0.03 | 0.03 | +0.01 | sell |
| Hennion & Walsh Asset Management, Inc. | 46,916 | 38,386 | -8,530 | 0.21 | 0.24 | +0.04 | sell |
| IRIDIAN ASSET MANAGEMENT LLC/CT | 83,553 | 73,783 | -9,770 | 3.99 | 4.96 | +0.97 | sell |
| MOODY ALDRICH PARTNERS LLC | 51,476 | 40,273 | -11,203 | 1.19 | 1.37 | +0.19 | sell |
| Clearbridge Investments, LLC | 57,667 | 46,326 | -11,341 | 0.01 | 0.01 | +0.00 | sell |
| LOOMIS SAYLES & CO L P | 330,125 | 315,391 | -14,734 | 0.05 | 0.07 | +0.02 | sell |
| PEREGRINE CAPITAL MANAGEMENT LLC | 64,521 | 46,633 | -17,888 | 0.24 | 0.26 | +0.03 | sell |
| TFG Asset Management GP Ltd | 46,456 | 26,934 | -19,522 | 0.75 | 1.04 | +0.28 | sell |
| Bellevue Group AG | 52,335 | 27,600 | -24,735 | 0.13 | 0.10 | -0.04 | sell |
| Cormorant Asset Management, LP | 100,000 | 75,000 | -25,000 | 0.84 | 0.63 | -0.20 | sell |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 326,318 | 278,835 | -47,483 | 3.06 | 4.52 | +1.46 | sell |
| Rhenman & Partners Asset Management AB | 172,800 | 114,800 | -58,000 | 2.32 | 1.96 | -0.36 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 445,000 | 367,578 | -77,422 | 0.09 | 0.10 | +0.02 | sell |
| Tri Locum Partners LP | 292,137 | 201,627 | -90,510 | 8.16 | 4.78 | -3.37 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 746,398 | 571,226 | -175,172 | 1.49 | 1.63 | +0.14 | sell |
| RTW INVESTMENTS, LP | 1,118,883 | 888,001 | -230,882 | 1.67 | 1.62 | -0.05 | sell |
| T. Rowe Price Investment Management, Inc. | 274,014 | 13,645 | -260,369 | 0.02 | 0.00 | -0.02 | sell |
| ORBIMED ADVISORS LLC | 531,800 | 253,121 | -278,679 | 1.55 | 0.95 | -0.60 | sell |
| PFM Health Sciences, LP | 530,332 | 251,562 | -278,770 | 4.95 | 4.58 | -0.37 | sell |
| Sofinnova Investments, Inc. | 393,499 | 12,266 | -381,233 | 2.61 | 0.10 | -2.52 | sell |
| BVF INC/IL | 486,757 | 45,757 | -441,000 | 2.40 | 0.28 | -2.12 | sell |