| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 6,726,808 | 7,559,495 | +832,687 | 1.13 | 1.59 | +0.46 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 4,142,283 | 5,954,429 | +1,812,146 | 0.30 | 0.53 | +0.23 | buy |
| BlackRock, Inc. | 6,178,376 | 5,894,972 | -283,404 | 0.00 | 0.00 | +0.00 | sell |
| Artisan Partners Limited Partnership | 6,410,900 | 5,830,205 | -580,695 | 0.26 | 0.28 | +0.02 | sell |
| VANGUARD GROUP INC | 5,768,149 | 5,776,198 | +8,049 | 0.00 | 0.00 | +0.00 | buy |
| EdgePoint Investment Group Inc. | 4,082,319 | 5,377,991 | +1,295,672 | 0.86 | 1.40 | +0.54 | buy |
| STATE STREET CORP | 3,089,063 | 3,627,818 | +538,755 | 0.00 | 0.00 | +0.00 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 2,120,206 | 1,902,829 | -217,377 | 0.03 | 0.04 | +0.00 | sell |
| Nikko Asset Management Americas, Inc. | 2,120,206 | 1,902,829 | -217,377 | 0.58 | 0.70 | +0.12 | sell |
| Soleus Capital Management, L.P. | 1,866,234 | 1,861,802 | -4,432 | 2.81 | 2.51 | -0.30 | sell |
| GOLDMAN SACHS GROUP INC | 1,627,020 | 1,696,594 | +69,574 | 0.01 | 0.01 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,793,850 | 1,497,746 | -296,104 | 0.04 | 0.03 | -0.01 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 1,448,413 | 1,459,274 | +10,861 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 1,463,085 | 1,361,355 | -101,730 | 0.08 | 0.08 | -0.00 | sell |
| Invesco Ltd. | 1,795,143 | 1,290,271 | -504,872 | 0.01 | 0.01 | -0.00 | sell |
| BAILLIE GIFFORD & CO | 1,262,739 | 1,276,195 | +13,456 | 0.03 | 0.03 | +0.01 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,123,697 | 1,173,100 | +49,403 | 0.01 | 0.01 | +0.00 | buy |
| First Light Asset Management, LLC | 1,194,883 | 1,140,771 | -54,112 | 3.17 | 2.77 | -0.40 | sell |
| MORGAN STANLEY | 1,492,106 | 866,356 | -625,750 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 838,064 | 865,634 | +27,570 | 0.01 | 0.01 | +0.00 | buy |
| Tao Capital Management LP | 828,815 | 828,815 | 0 | 17.64 | 22.63 | +4.99 | hold |
| DIMENSIONAL FUND ADVISORS LP | 790,893 | 815,369 | +24,476 | 0.00 | 0.01 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 299,813 | 813,122 | +513,309 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 514,928 | 662,317 | +147,389 | 0.00 | 0.00 | +0.00 | buy |
| JENNISON ASSOCIATES LLC | 634,600 | 618,933 | -15,667 | 0.01 | 0.01 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 584,694 | 591,180 | +6,486 | 0.02 | 0.03 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 246,236 | 579,370 | +333,134 | 0.01 | 0.03 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 573,632 | 548,392 | -25,240 | 0.00 | 0.00 | +0.00 | sell |
| STEMPOINT CAPITAL LP | 0 | 518,355 | +518,355 | 0.00 | 2.82 | +2.82 | buy |
| NORTHERN TRUST CORP | 525,042 | 504,838 | -20,204 | 0.00 | 0.00 | +0.00 | sell |
| Freshford Capital Management, LLC | 0 | 420,171 | +420,171 | 0.00 | 5.35 | +5.35 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 121,465 | 415,609 | +294,144 | 0.00 | 0.01 | +0.01 | buy |
| CITIGROUP INC | 93,458 | 401,282 | +307,824 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 450,374 | 399,354 | -51,020 | 0.00 | 0.00 | -0.00 | sell |
| Blue Water Life Science Advisors, LP | 0 | 383,000 | +383,000 | 0.00 | 7.63 | +7.63 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 265,851 | 371,552 | +105,701 | 0.51 | 0.81 | +0.31 | buy |
| Aberdeen Group plc | 320,283 | 308,116 | -12,167 | 0.01 | 0.02 | +0.00 | sell |
| Nuveen, LLC | 552,141 | 290,556 | -261,585 | 0.00 | 0.00 | -0.00 | sell |
| PEREGRINE CAPITAL MANAGEMENT LLC | 292,153 | 288,283 | -3,870 | 0.25 | 0.28 | +0.03 | sell |
| SEI INVESTMENTS CO | 296,918 | 270,099 | -26,819 | 0.01 | 0.01 | -0.00 | sell |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 268,326 | 269,093 | +767 | 0.05 | 0.06 | +0.01 | buy |
| OSTERWEIS CAPITAL MANAGEMENT INC | 0 | 256,878 | +256,878 | 0.00 | 0.34 | +0.34 | buy |
| JUPITER ASSET MANAGEMENT LTD | 245,098 | 243,669 | -1,429 | 0.06 | 0.06 | +0.00 | sell |
| Pictet Asset Management Holding SA | 106,767 | 222,647 | +115,880 | 0.00 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,018,234 | 215,147 | -803,087 | 0.00 | 0.00 | -0.00 | sell |
| Ensign Peak Advisors, Inc | 226,272 | 212,593 | -13,679 | 0.01 | 0.01 | +0.00 | sell |
| Trexquant Investment LP | 332,698 | 198,473 | -134,225 | 0.10 | 0.06 | -0.04 | sell |
| BARCLAYS PLC | 226,668 | 194,071 | -32,597 | 0.00 | 0.00 | +0.00 | sell |
| Bank of New York Mellon Corp | 498,261 | 182,941 | -315,320 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 572,435 | 171,972 | -400,463 | 0.02 | 0.01 | -0.01 | sell |
| Legal & General Group Plc | 125,286 | 171,206 | +45,920 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 153,172 | 153,172 | 0 | 0.02 | 0.02 | +0.00 | hold |
| Schonfeld Strategic Advisors LLC | 65,449 | 139,893 | +74,444 | 0.01 | 0.02 | +0.01 | buy |
| ODDO BHF ASSET MANAGEMENT SAS | 171,787 | 135,650 | -36,137 | 0.18 | 0.16 | -0.02 | sell |
| Neuberger Berman Group LLC | 161,174 | 135,622 | -25,552 | 0.00 | 0.00 | -0.00 | sell |
| Vestmark Advisory Solutions, Inc. | 117,249 | 129,990 | +12,741 | 0.06 | 0.06 | -0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 207,908 | 129,552 | -78,356 | 0.00 | 0.00 | -0.00 | sell |
| Swiss National Bank | 116,100 | 119,000 | +2,900 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 114,268 | 114,258 | -10 | 0.01 | 0.01 | +0.00 | sell |
| NATIXIS | 0 | 103,688 | +103,688 | 0.00 | 0.01 | +0.01 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 497,138 | 103,117 | -394,021 | 0.06 | 0.01 | -0.04 | sell |
| FRED ALGER MANAGEMENT, LLC | 97,061 | 94,111 | -2,950 | 0.01 | 0.01 | +0.00 | sell |
| RHUMBLINE ADVISERS | 95,207 | 91,122 | -4,085 | 0.00 | 0.00 | +0.00 | sell |
| BLAIR WILLIAM & CO/IL | 59,079 | 81,561 | +22,482 | 0.00 | 0.01 | +0.00 | buy |
| Aquatic Capital Management LLC | 22,263 | 78,469 | +56,206 | 0.01 | 0.07 | +0.06 | buy |
| SG Americas Securities, LLC | 16,984 | 76,484 | +59,500 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 75,463 | 76,318 | +855 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 46,760 | 74,819 | +28,059 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 73,127 | +73,127 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 16,955 | 70,753 | +53,798 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 219,532 | 68,937 | -150,595 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 66,600 | 66,524 | -76 | 0.00 | 0.00 | +0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 78,350 | 66,027 | -12,323 | 0.00 | 0.00 | +0.00 | sell |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 65,590 | 65,122 | -468 | 0.00 | 0.00 | +0.00 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 48,900 | 60,200 | +11,300 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 53,850 | 58,985 | +5,135 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 58,345 | 58,337 | -8 | 0.00 | 0.00 | +0.00 | sell |
| Conestoga Capital Advisors, LLC | 55,600 | 56,785 | +1,185 | 0.03 | 0.03 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 100,515 | 55,671 | -44,844 | 0.00 | 0.00 | -0.00 | sell |
| FRANKLIN RESOURCES INC | 258,699 | 53,881 | -204,818 | 0.00 | 0.00 | -0.00 | sell |
| LPL Financial LLC | 35,399 | 53,043 | +17,644 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 51,284 | 51,335 | +51 | 0.00 | 0.00 | +0.00 | buy |
| Clarius Group, LLC | 49,635 | 49,635 | 0 | 0.08 | 0.09 | +0.01 | hold |
| Mitsubishi UFJ Asset Management Co., Ltd. | 39,964 | 44,668 | +4,704 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 24,654 | 42,355 | +17,701 | 0.02 | 0.04 | +0.02 | buy |
| ALGERT GLOBAL LLC | 60,301 | 40,601 | -19,700 | 0.03 | 0.02 | -0.01 | sell |
| HighMark Wealth Management LLC | 39,462 | 39,462 | 0 | 0.49 | 0.51 | +0.02 | hold |
| ENVESTNET ASSET MANAGEMENT INC | 49,840 | 38,649 | -11,191 | 0.00 | 0.00 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 47,245 | 37,555 | -9,690 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 75,797 | 35,717 | -40,080 | 0.00 | 0.00 | -0.00 | sell |
| Maxi Investments CY Ltd | 0 | 35,000 | +35,000 | 0.00 | 0.20 | +0.20 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 37,186 | 34,547 | -2,639 | 0.00 | 0.00 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 96,281 | 33,348 | -62,933 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 34,727 | 33,236 | -1,491 | 0.00 | 0.01 | +0.00 | sell |
| ROYAL BANK OF CANADA | 128,490 | 33,234 | -95,256 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 115,245 | 32,049 | -83,196 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 26,000 | 31,400 | +5,400 | 0.00 | 0.00 | +0.00 | buy |
| BENJAMIN EDWARDS INC | 28,323 | 29,632 | +1,309 | 0.01 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 27,581 | +27,581 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 29,101 | 26,323 | -2,778 | 0.01 | 0.01 | -0.00 | sell |