| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 7,523,877 | 7,289,810 | -234,067 | 0.02 | 0.03 | +0.00 | sell |
| VANGUARD GROUP INC | 4,246,749 | 4,712,147 | +465,398 | 0.00 | 0.01 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,985,817 | 1,809,154 | -176,663 | 0.03 | 0.04 | +0.00 | sell |
| T. Rowe Price Investment Management, Inc. | 2,939,919 | 1,747,089 | -1,192,830 | 0.09 | 0.07 | -0.02 | sell |
| Champlain Investment Partners, LLC | 1,572,309 | 1,365,279 | -207,030 | 0.44 | 0.51 | +0.07 | sell |
| LOOMIS SAYLES & CO L P | 1,351,000 | 1,261,608 | -89,392 | 0.09 | 0.11 | +0.01 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,467,659 | 1,169,302 | -298,357 | 0.01 | 0.01 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 1,116,249 | 1,118,642 | +2,393 | 0.01 | 0.01 | +0.00 | buy |
| STATE STREET CORP | 1,067,502 | 1,113,339 | +45,837 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 961,341 | 1,022,344 | +61,003 | 0.00 | 0.01 | +0.00 | buy |
| CPMG Inc | 5,328,867 | 958,334 | -4,370,533 | 95.57 | 87.55 | -8.02 | sell |
| JPMORGAN CHASE & CO | 73,189 | 896,747 | +823,558 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 766,744 | 762,694 | -4,050 | 1.81 | 2.15 | +0.34 | sell |
| Bellevue Group AG | 890,114 | 669,049 | -221,065 | 0.67 | 0.66 | -0.01 | sell |
| BANK OF AMERICA CORP /DE/ | 231,616 | 647,215 | +415,599 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 306,167 | 568,505 | +262,338 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 105,859 | 538,662 | +432,803 | 0.00 | 0.01 | +0.01 | buy |
| BNP Paribas Asset Management Holding S.A. | 627,822 | 519,950 | -107,872 | 0.08 | 0.08 | -0.00 | sell |
| LORD, ABBETT & CO. LLC | 252,310 | 515,125 | +262,815 | 0.04 | 0.10 | +0.06 | buy |
| Artisan Partners Limited Partnership | 353,813 | 477,234 | +123,421 | 0.03 | 0.04 | +0.02 | buy |
| Rhenman & Partners Asset Management AB | 487,063 | 440,000 | -47,063 | 2.28 | 2.58 | +0.30 | sell |
| BLAIR WILLIAM & CO/IL | 429,793 | 420,305 | -9,488 | 0.07 | 0.08 | +0.01 | sell |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 476,505 | 399,895 | -76,610 | 0.01 | 0.01 | +0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 227,004 | 372,061 | +145,057 | 0.04 | 0.08 | +0.04 | buy |
| NORTHERN TRUST CORP | 366,424 | 358,749 | -7,675 | 0.00 | 0.00 | +0.00 | sell |
| JOHNSON & JOHNSON | 357,939 | 357,939 | 0 | 0.40 | 5.46 | +5.06 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 341,291 | 355,900 | +14,609 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 277,464 | 349,394 | +71,930 | 0.14 | 0.21 | +0.07 | buy |
| Bank of New York Mellon Corp | 326,013 | 300,813 | -25,200 | 0.00 | 0.00 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 149,117 | 279,963 | +130,846 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 187,860 | 277,080 | +89,220 | 0.01 | 0.02 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 244,675 | 265,099 | +20,424 | 0.03 | 0.04 | +0.01 | buy |
| Point72 Europe (London) LLP | 320,431 | 259,231 | -61,200 | 1.47 | 1.34 | -0.14 | sell |
| Eagle Health Investments LP | 337,218 | 257,089 | -80,129 | 3.18 | 2.81 | -0.37 | sell |
| NEXT CENTURY GROWTH INVESTORS LLC | 89,540 | 239,591 | +150,051 | 0.38 | 1.22 | +0.83 | buy |
| Chicago Capital, LLC | 0 | 232,983 | +232,983 | 0.00 | 0.42 | +0.42 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 239,876 | 229,595 | -10,281 | 0.01 | 0.01 | +0.00 | sell |
| PERCEPTIVE ADVISORS LLC | 210,659 | 210,659 | 0 | 0.18 | 0.31 | +0.13 | hold |
| Allspring Global Investments Holdings, LLC | 199,027 | 187,605 | -11,422 | 0.02 | 0.02 | +0.00 | sell |
| FEDERATED HERMES, INC. | 20,635 | 183,420 | +162,785 | 0.00 | 0.03 | +0.02 | buy |
| OSTERWEIS CAPITAL MANAGEMENT INC | 104,155 | 172,345 | +68,190 | 0.30 | 0.54 | +0.24 | buy |
| TRANSATLANTIQUE PRIVATE WEALTH LLC | 0 | 150,000 | +150,000 | 0.00 | 3.74 | +3.74 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 87,518 | 141,631 | +54,113 | 0.01 | 0.01 | +0.01 | buy |
| M&G Plc | 0 | 139,462 | +139,462 | 0.00 | 0.03 | +0.03 | buy |
| Frank, Rimerman Advisors LLC | 192,082 | 122,082 | -70,000 | 1.83 | 0.53 | -1.30 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 52,076 | 113,377 | +61,301 | 0.00 | 0.00 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 78,286 | 111,337 | +33,051 | 0.00 | 0.01 | +0.00 | buy |
| JANE STREET GROUP, LLC | 60,697 | 108,883 | +48,186 | 0.00 | 0.01 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 182,790 | 104,148 | -78,642 | 0.01 | 0.01 | -0.00 | sell |
| Aberdeen Group plc | 104,707 | 102,675 | -2,032 | 0.01 | 0.01 | +0.00 | sell |
| Lisanti Capital Growth, LLC | 100,655 | 99,240 | -1,415 | 1.21 | 1.46 | +0.24 | sell |
| Robocap Asset Management Ltd | 87,148 | 93,582 | +6,434 | 2.95 | 3.56 | +0.61 | buy |
| CASTLEARK MANAGEMENT LLC | 57,490 | 93,240 | +35,750 | 0.12 | 0.23 | +0.11 | buy |
| MILLENNIUM MANAGEMENT LLC | 53,491 | 92,692 | +39,201 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 89,700 | 90,200 | +500 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 86,884 | 85,906 | -978 | 0.01 | 0.01 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 58,848 | 85,327 | +26,479 | 0.00 | 0.00 | +0.00 | buy |
| LYELL WEALTH MANAGEMENT, LP | 84,203 | 84,203 | 0 | 0.42 | 0.49 | +0.07 | hold |
| Taylor Frigon Capital Management LLC | 82,555 | 81,880 | -675 | 1.94 | 2.38 | +0.44 | sell |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 60,116 | 80,764 | +20,648 | 0.59 | 0.92 | +0.34 | buy |
| Nicholas Investment Partners, LP | 0 | 76,232 | +76,232 | 0.00 | 0.48 | +0.48 | buy |
| WELLS FARGO & COMPANY/MN | 38,045 | 74,906 | +36,861 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 52,846 | 69,595 | +16,749 | 0.00 | 0.00 | +0.00 | buy |
| ArrowMark Colorado Holdings LLC | 117,964 | 69,471 | -48,493 | 0.07 | 0.05 | -0.01 | sell |
| Evolutionary Tree Capital Management, LLC | 49,887 | 66,239 | +16,352 | 2.48 | 4.16 | +1.68 | buy |
| AlTi Global, Inc. | 65,946 | 65,946 | 0 | 0.09 | 0.11 | +0.02 | hold |
| Lighthouse Investment Partners, LLC | 26,300 | 64,313 | +38,013 | 0.06 | 0.22 | +0.16 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 73,031 | 62,562 | -10,469 | 0.00 | 0.00 | +0.00 | sell |
| Trexquant Investment LP | 6,116 | 62,161 | +56,045 | 0.01 | 0.06 | +0.05 | buy |
| RHUMBLINE ADVISERS | 56,079 | 61,872 | +5,793 | 0.00 | 0.00 | +0.00 | buy |
| Numerai GP LLC | 52,642 | 59,449 | +6,807 | 1.12 | 1.32 | +0.20 | buy |
| Informed Momentum Co LLC | 0 | 58,660 | +58,660 | 0.00 | 0.58 | +0.58 | buy |
| TWO SIGMA ADVISERS, LP | 93,400 | 54,800 | -38,600 | 0.01 | 0.01 | -0.00 | sell |
| Invesco Ltd. | 18,520 | 51,480 | +32,960 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 34,396 | 46,473 | +12,077 | 0.01 | 0.01 | +0.00 | buy |
| KRS Capital Management, LLC | 0 | 46,105 | +46,105 | 0.00 | 2.11 | +2.11 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 45,966 | +45,966 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 0 | 45,509 | +45,509 | 0.00 | 0.01 | +0.01 | buy |
| Walleye Capital LLC | 0 | 45,335 | +45,335 | 0.00 | 0.03 | +0.03 | buy |
| Legal & General Group Plc | 44,753 | 45,052 | +299 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 44,931 | 44,518 | -413 | 0.00 | 0.00 | +0.00 | sell |
| FORMULA GROWTH LTD | 0 | 44,440 | +44,440 | 0.00 | 0.99 | +0.99 | buy |
| Trek Financial, LLC | 0 | 41,724 | +41,724 | 0.00 | 0.20 | +0.20 | buy |
| SEI INVESTMENTS CO | 22,777 | 36,136 | +13,359 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 36,051 | +36,051 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 30,574 | 30,889 | +315 | 0.09 | 0.09 | +0.01 | buy |
| State of New Jersey Common Pension Fund D | 57,087 | 29,015 | -28,072 | 0.01 | 0.01 | -0.00 | sell |
| CITADEL ADVISORS LLC | 18,224 | 27,400 | +9,176 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 27,027 | +27,027 | 0.00 | 0.05 | +0.05 | buy |
| MetLife Investment Management, LLC | 20,476 | 24,536 | +4,060 | 0.01 | 0.01 | +0.00 | buy |
| Pacific Capital Partners Ltd | 21,699 | 24,299 | +2,600 | 0.70 | 0.98 | +0.28 | buy |
| JANUS HENDERSON GROUP PLC | 18,521 | 24,296 | +5,775 | 0.00 | 0.00 | +0.00 | buy |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 24,102 | 24,102 | 0 | 0.21 | 0.23 | +0.02 | hold |
| Amundi | 21,702 | 21,702 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VELA Investment Management, LLC | 20,487 | 20,487 | 0 | 0.37 | 0.44 | +0.07 | hold |
| DEUTSCHE BANK AG\ | 22,395 | 20,217 | -2,178 | 0.00 | 0.00 | +0.00 | sell |
| BAILARD, INC. | 21,386 | 18,386 | -3,000 | 0.03 | 0.03 | +0.00 | sell |
| Dynamic Technology Lab Private Ltd | 0 | 17,835 | +17,835 | 0.00 | 0.12 | +0.12 | buy |
| BESSEMER GROUP INC | 21,025 | 17,705 | -3,320 | 0.00 | 0.00 | +0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 20,983 | 17,587 | -3,396 | 0.00 | 0.00 | +0.00 | sell |