| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Vestal Point Capital, LP | 3,925,000 | 4,725,000 | +800,000 | 2.81 | 2.03 | -0.78 | buy |
| Nantahala Capital Management, LLC | 2,958,027 | 3,088,082 | +130,055 | 2.00 | 1.57 | -0.43 | buy |
| 683 Capital Management, LLC | 1,693,000 | 1,975,000 | +282,000 | 1.15 | 1.05 | -0.10 | buy |
| MORGAN STANLEY | 1,759,818 | 1,518,228 | -241,590 | 0.00 | 0.00 | -0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 1,241,500 | 1,241,500 | 0 | 0.01 | 0.01 | -0.00 | hold |
| VANGUARD GROUP INC | 962,796 | 1,072,536 | +109,740 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 749,354 | 969,504 | +220,150 | 0.00 | 0.00 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 560,331 | 850,100 | +289,769 | 0.01 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 706,670 | 736,724 | +30,054 | 0.01 | 0.00 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 820,260 | 709,435 | -110,825 | 0.00 | 0.00 | -0.00 | sell |
| MACQUARIE GROUP LTD | 706,166 | 706,166 | 0 | 0.01 | 0.00 | -0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 263,199 | 613,490 | +350,291 | 0.01 | 0.01 | +0.00 | buy |
| Privium Fund Management B.V. | 444,148 | 578,915 | +134,767 | 0.86 | 0.80 | -0.05 | buy |
| CITADEL ADVISORS LLC | 171,044 | 550,567 | +379,523 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 425,000 | 525,000 | +100,000 | 0.03 | 0.02 | -0.00 | buy |
| J. Goldman & Co LP | 0 | 510,505 | +510,505 | 0.00 | 0.12 | +0.12 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 168,724 | 503,883 | +335,159 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 479,675 | 499,820 | +20,145 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 455,472 | 474,579 | +19,107 | 0.00 | 0.00 | -0.00 | buy |
| Ikarian Capital, LLC | 157,365 | 469,133 | +311,768 | 0.29 | 0.66 | +0.37 | buy |
| Aberdeen Group plc | 400,480 | 400,480 | 0 | 0.01 | 0.00 | -0.00 | hold |
| BRIDGER MANAGEMENT, LLC | 362,349 | 362,349 | 0 | 0.94 | 0.85 | -0.09 | hold |
| GOLDMAN SACHS GROUP INC | 695,345 | 362,333 | -333,012 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 274,869 | 314,457 | +39,588 | 0.00 | 0.00 | -0.00 | buy |
| Verition Fund Management LLC | 303,435 | 310,567 | +7,132 | 0.02 | 0.02 | -0.01 | buy |
| ADAR1 Capital Management, LLC | 0 | 292,850 | +292,850 | 0.00 | 0.42 | +0.42 | buy |
| TWO SIGMA ADVISERS, LP | 28,300 | 289,500 | +261,200 | 0.00 | 0.00 | +0.00 | buy |
| PFM Health Sciences, LP | 0 | 274,540 | +274,540 | 0.00 | 0.07 | +0.07 | buy |
| GROUP ONE TRADING LLC | 50,281 | 254,027 | +203,746 | 0.01 | 0.05 | +0.04 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 264,513 | 246,410 | -18,103 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 121,976 | 236,277 | +114,301 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 222,389 | 235,490 | +13,101 | 0.00 | 0.00 | -0.00 | buy |
| Carlson Capital, L.P. | 195,000 | 227,400 | +32,400 | 0.11 | 0.10 | -0.01 | buy |
| JANE STREET GROUP, LLC | 105,202 | 215,669 | +110,467 | 0.00 | 0.00 | +0.00 | buy |
| NORGES BANK | 207,100 | 207,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 3,478,872 | 203,802 | -3,275,070 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 36,739 | 192,814 | +156,075 | 0.01 | 0.03 | +0.02 | buy |
| Point72 Asset Management, L.P. | 931,285 | 185,224 | -746,061 | 0.02 | 0.00 | -0.02 | sell |
| Mirae Asset Global Investments Co., Ltd. | 90,354 | 157,312 | +66,958 | 0.00 | 0.01 | +0.01 | buy |
| TANG CAPITAL MANAGEMENT LLC | 600,000 | 133,921 | -466,079 | 0.38 | 0.07 | -0.30 | sell |
| BANQUE PICTET & CIE SA | 144,585 | 132,181 | -12,404 | 0.01 | 0.01 | -0.00 | sell |
| PDT Partners, LLC | 100,201 | 121,865 | +21,664 | 0.07 | 0.06 | -0.02 | buy |
| ExodusPoint Capital Management, LP | 0 | 116,708 | +116,708 | 0.00 | 0.01 | +0.01 | buy |
| Invesco Ltd. | 35,799 | 108,598 | +72,799 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 108,882 | 99,676 | -9,206 | 0.02 | 0.01 | -0.01 | sell |
| NORTHERN TRUST CORP | 87,135 | 84,904 | -2,231 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 21,599 | 84,587 | +62,988 | 0.00 | 0.01 | +0.01 | buy |
| Sigma Planning Corp | 28,745 | 82,655 | +53,910 | 0.02 | 0.01 | -0.00 | buy |
| Walleye Capital LLC | 140,755 | 81,167 | -59,588 | 0.01 | 0.00 | -0.01 | sell |
| Marex Group plc | 80,000 | 80,000 | 0 | 0.02 | 0.01 | -0.01 | hold |
| DIAMOND HILL CAPITAL MANAGEMENT INC | 54,185 | 76,630 | +22,445 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 95,000 | 71,064 | -23,936 | 0.02 | 0.01 | -0.01 | sell |
| SANDERS MORRIS HARRIS LLC | 68,070 | 68,070 | 0 | 0.23 | 0.06 | -0.16 | hold |
| Pale Fire Capital SE | 65,600 | 65,600 | 0 | 0.07 | 0.05 | -0.02 | hold |
| Shay Capital LLC | 13,052 | 64,826 | +51,774 | 0.03 | 0.10 | +0.06 | buy |
| MOORE CAPITAL MANAGEMENT, LP | 60,000 | 60,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Y-Intercept (Hong Kong) Ltd | 13,180 | 59,292 | +46,112 | 0.01 | 0.02 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 44,496 | 59,057 | +14,561 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 26,423 | 53,690 | +27,267 | 0.12 | 0.18 | +0.05 | buy |
| ROYAL BANK OF CANADA | 80,273 | 53,683 | -26,590 | 0.00 | 0.00 | -0.00 | sell |
| Allianz Asset Management GmbH | 50,642 | 50,642 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pennant Investors, LP | 48,500 | 48,500 | 0 | 0.10 | 0.07 | -0.03 | hold |
| HRT FINANCIAL LP | 56,881 | 45,035 | -11,846 | 0.00 | 0.00 | -0.00 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 16,683 | 40,652 | +23,969 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 743,910 | 39,989 | -703,921 | 0.01 | 0.00 | -0.01 | sell |
| Henry James International Management Inc. | 41,286 | 39,518 | -1,768 | 0.10 | 0.06 | -0.04 | sell |
| Engineers Gate Manager LP | 50,794 | 38,518 | -12,276 | 0.01 | 0.01 | -0.00 | sell |
| Clear Harbor Asset Management, LLC | 12,900 | 35,500 | +22,600 | 0.01 | 0.02 | +0.01 | buy |
| Brevan Howard Capital Management LP | 23,350 | 35,073 | +11,723 | 0.02 | 0.02 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 30,883 | 34,866 | +3,983 | 0.04 | 0.02 | -0.02 | buy |
| Worth Venture Partners, LLC | 0 | 34,300 | +34,300 | 0.00 | 1.25 | +1.25 | buy |
| Corient Private Wealth LLC | 0 | 32,599 | +32,599 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 21,800 | 32,400 | +10,600 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 7,800 | 32,043 | +24,243 | 0.01 | 0.04 | +0.03 | buy |
| Atom Investors LP | 0 | 30,569 | +30,569 | 0.00 | 0.02 | +0.02 | buy |
| FMR LLC | 48,782 | 28,806 | -19,976 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 19,020 | 28,790 | +9,770 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 168,002 | 26,708 | -141,294 | 0.00 | 0.00 | -0.00 | sell |
| Bridgefront Capital, LLC | 0 | 23,681 | +23,681 | 0.00 | 0.09 | +0.09 | buy |
| TUDOR INVESTMENT CORP ET AL | 25,953 | 23,653 | -2,300 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 23,229 | 23,515 | +286 | 0.00 | 0.00 | -0.00 | buy |
| Laurion Capital Management LP | 0 | 17,622 | +17,622 | 0.00 | 0.00 | +0.00 | buy |
| Regal Investment Advisors LLC | 16,093 | 16,359 | +266 | 0.01 | 0.01 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 16,100 | 16,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Schonfeld Strategic Advisors LLC | 124,549 | 15,900 | -108,649 | 0.01 | 0.00 | -0.01 | sell |
| Advisory Services Network, LLC | 12,500 | 14,000 | +1,500 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,763 | 13,168 | +10,405 | 0.00 | 0.00 | +0.00 | buy |
| Mraz, Amerine & Associates, Inc. | 13,604 | 13,109 | -495 | 0.02 | 0.01 | -0.01 | sell |
| WELLS FARGO & COMPANY/MN | 9,077 | 11,207 | +2,130 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 274,448 | 11,040 | -263,408 | 0.02 | 0.00 | -0.02 | sell |
| Vanguard Personalized Indexing Management, LLC | 12,659 | 10,995 | -1,664 | 0.00 | 0.00 | -0.00 | sell |
| VIRTUS ADVISERS, LLC | 11,430 | 10,693 | -737 | 0.05 | 0.03 | -0.02 | sell |
| Bank Pictet & Cie (Europe) AG | 11,023 | 10,577 | -446 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 6,258 | 9,922 | +3,664 | 0.01 | 0.01 | -0.00 | buy |
| Aquatic Capital Management LLC | 0 | 8,800 | +8,800 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 5,688 | 5,688 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 4,088 | 3,691 | -397 | 0.00 | 0.00 | -0.00 | sell |
| Future Financial Wealth Managment LLC | 0 | 2,000 | +2,000 | 0.00 | 0.01 | +0.01 | buy |
| LAZARD ASSET MANAGEMENT LLC | 3,040 | 1,958 | -1,082 | 0.00 | 0.00 | -0.00 | sell |
| NATIONAL BANK OF CANADA /FI/ | 683 | 1,545 | +862 | 0.00 | 0.00 | +0.00 | buy |