| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Assenagon Asset Management S.A. | 227,611 | 816,384 | +588,773 | 0.01 | 0.02 | +0.01 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 426,955 | 806,715 | +379,760 | 0.02 | 0.02 | +0.00 | buy |
| VANGUARD GROUP INC | 4,876,881 | 5,113,782 | +236,901 | 0.00 | 0.00 | -0.00 | buy |
| Integral Health Asset Management, LLC | 760,000 | 950,000 | +190,000 | 1.57 | 1.11 | -0.47 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 151,753 | +151,753 | 0.00 | 0.12 | +0.12 | buy |
| MILLENNIUM MANAGEMENT LLC | 165,821 | 306,487 | +140,666 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 20,010 | 146,259 | +126,249 | 0.00 | 0.01 | +0.00 | buy |
| Hudson Bay Capital Management LP | 44,900 | 165,000 | +120,100 | 0.01 | 0.01 | +0.01 | buy |
| JANE STREET GROUP, LLC | 0 | 94,970 | +94,970 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 950,551 | 1,044,614 | +94,063 | 0.00 | 0.00 | -0.00 | buy |
| Allianz Asset Management GmbH | 0 | 92,600 | +92,600 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 89,984 | 179,740 | +89,756 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 108,580 | 188,235 | +79,655 | 0.03 | 0.04 | +0.01 | buy |
| Jump Financial, LLC | 0 | 72,975 | +72,975 | 0.00 | 0.02 | +0.02 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 70,199 | +70,199 | 0.00 | 0.02 | +0.02 | buy |
| Qube Research & Technologies Ltd | 42,972 | 109,982 | +67,010 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 55,576 | +55,576 | 0.00 | 0.01 | +0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 42,292 | +42,292 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 355 | 42,000 | +41,645 | 0.00 | 0.07 | +0.07 | buy |
| STIFEL FINANCIAL CORP | 90,595 | 131,717 | +41,122 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 13,293 | 52,651 | +39,358 | 0.04 | 0.05 | +0.01 | buy |
| MARSHALL WACE, LLP | 0 | 39,093 | +39,093 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 50,643 | 89,605 | +38,962 | 0.02 | 0.02 | -0.01 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 38,844 | +38,844 | 0.00 | 0.02 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 343,615 | 380,684 | +37,069 | 0.00 | 0.00 | -0.00 | buy |
| WINTON GROUP Ltd | 42,704 | 76,840 | +34,136 | 0.06 | 0.06 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 162,699 | 196,487 | +33,788 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 38,544 | 70,958 | +32,414 | 0.00 | 0.00 | -0.00 | buy |
| Dynamic Technology Lab Private Ltd | 16,952 | 48,954 | +32,002 | 0.04 | 0.06 | +0.03 | buy |
| Bank of New York Mellon Corp | 310,668 | 339,514 | +28,846 | 0.00 | 0.00 | -0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 106,284 | 134,190 | +27,906 | 0.12 | 0.08 | -0.04 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 26,407 | +26,407 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 20,379 | +20,379 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 19,967 | +19,967 | 0.00 | 0.01 | +0.01 | buy |
| Steward Partners Investment Advisory, LLC | 8,263 | 27,863 | +19,600 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 57,200 | 75,900 | +18,700 | 0.00 | 0.00 | -0.00 | buy |
| Redmile Group, LLC | 4,551,556 | 4,569,802 | +18,246 | 3.52 | 3.23 | -0.29 | buy |
| CITADEL ADVISORS LLC | 108,497 | 126,392 | +17,895 | 0.00 | 0.00 | -0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 0 | 15,857 | +15,857 | 0.00 | 0.03 | +0.03 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 83,993 | 99,676 | +15,683 | 0.01 | 0.01 | -0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 15,222 | +15,222 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 0 | 12,375 | +12,375 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 64,105 | 74,872 | +10,767 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 8,462 | 18,989 | +10,527 | 0.00 | 0.00 | +0.00 | buy |
| Diversified Trust Co | 0 | 10,352 | +10,352 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 216,211 | 225,417 | +9,206 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 109,539 | 118,526 | +8,987 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 16,629 | 25,005 | +8,376 | 0.00 | 0.00 | -0.00 | buy |
| MPM BioImpact LLC | 549,078 | 557,076 | +7,998 | 1.86 | 1.01 | -0.85 | buy |
| Invesco Ltd. | 142,044 | 149,412 | +7,368 | 0.00 | 0.00 | -0.00 | buy |
| CANADA LIFE ASSURANCE Co | 37,211 | 44,392 | +7,181 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,246 | 9,314 | +7,068 | 0.00 | 0.00 | +0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 11,732 | 18,782 | +7,050 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 20,449 | 27,189 | +6,740 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 26,849 | 32,652 | +5,803 | 0.00 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 111,840 | 117,580 | +5,740 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 14,527 | 19,916 | +5,389 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 5,255 | +5,255 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 29,635 | 34,844 | +5,209 | 0.00 | 0.00 | -0.00 | buy |
| Sigma Planning Corp | 27,575 | 32,509 | +4,934 | 0.02 | 0.01 | -0.01 | buy |
| AMERIPRISE FINANCIAL INC | 270,641 | 274,802 | +4,161 | 0.00 | 0.00 | -0.00 | buy |
| Lion Point Capital, LP | 32,500 | 36,250 | +3,750 | 1.31 | 1.33 | +0.02 | buy |
| Vident Advisory, LLC | 9,532 | 12,918 | +3,386 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 15,360 | 18,375 | +3,015 | 0.00 | 0.00 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 18,177 | 21,100 | +2,923 | 0.00 | 0.00 | -0.00 | buy |
| Louisiana State Employees Retirement System | 20,000 | 22,800 | +2,800 | 0.01 | 0.01 | -0.00 | buy |
| VIRTUS ADVISERS, LLC | 4,159 | 6,921 | +2,762 | 0.05 | 0.04 | -0.01 | buy |
| Aquatic Capital Management LLC | 0 | 2,600 | +2,600 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 35,111 | 37,619 | +2,508 | 0.00 | 0.00 | -0.00 | buy |
| Arizona State Retirement System | 9,672 | 11,669 | +1,997 | 0.00 | 0.00 | -0.00 | buy |
| State of Alaska, Department of Revenue | 24,656 | 26,605 | +1,949 | 0.01 | 0.00 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 50,024 | 51,369 | +1,345 | 0.00 | 0.00 | -0.00 | buy |
| AMALGAMATED BANK | 12,386 | 13,613 | +1,227 | 0.00 | 0.00 | -0.00 | buy |
| nVerses Capital, LLC | 0 | 1,200 | +1,200 | 0.00 | 0.01 | +0.01 | buy |
| Maryland State Retirement & Pension System | 14,733 | 15,800 | +1,067 | 0.01 | 0.00 | -0.00 | buy |
| Amundi | 7,183 | 7,988 | +805 | 0.00 | 0.00 | -0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 48 | 593 | +545 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 431,785 | 432,250 | +465 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 16,300 | 16,646 | +346 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 531 | 855 | +324 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 11,841 | 12,113 | +272 | 0.00 | 0.00 | -0.00 | buy |
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND | 10,845 | 11,045 | +200 | 0.00 | 0.00 | -0.00 | buy |
| ADAR1 Capital Management, LLC | 2,500 | 2,700 | +200 | 0.01 | 0.01 | -0.01 | buy |
| Smartleaf Asset Management LLC | 0 | 97 | +97 | 0.00 | 0.00 | +0.00 | buy |
| UMB Bank, n.a. | 16 | 77 | +61 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 34,387 | 34,412 | +25 | 0.07 | 0.04 | -0.03 | buy |
| Arax Advisory Partners | 0 | 23 | +23 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 5 | 18 | +13 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 84 | 94 | +10 | 0.00 | 0.00 | -0.00 | buy |
| INNEALTA CAPITAL, LLC | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Artal Group S.A. | 250,000 | 250,000 | 0 | 0.14 | 0.08 | -0.06 | hold |
| Ameritas Investment Partners, Inc. | 4,037 | 4,037 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRAXIS INVESTMENT MANAGEMENT INC | 11,450 | 11,450 | 0 | 0.02 | 0.01 | -0.00 | hold |
| WASHINGTON TRUST Co | 187 | 187 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 59,027 | 59,027 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FARMERS & MERCHANTS INVESTMENTS INC | 25 | 25 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRINCIPAL SECURITIES, INC. | 189 | 189 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MACQUARIE GROUP LTD | 149,000 | 149,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MOORE CAPITAL MANAGEMENT, LP | 100,000 | 100,000 | 0 | 0.04 | 0.03 | -0.02 | hold |