| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 0 | 912,552 | +912,552 | 0.00 | 0.34 | +0.34 | buy |
| Octagon Capital Advisors LP | 488,000 | 1,115,000 | +627,000 | 3.64 | 3.68 | +0.04 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 600,000 | +600,000 | 0.00 | 0.88 | +0.88 | buy |
| Cormorant Asset Management, LP | 2,025,000 | 2,375,000 | +350,000 | 5.33 | 2.60 | -2.73 | buy |
| Altium Capital Management LLC | 0 | 195,000 | +195,000 | 0.00 | 1.20 | +1.20 | buy |
| STATE STREET CORP | 442,333 | 595,576 | +153,243 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 30,124 | 172,630 | +142,506 | 0.00 | 0.01 | +0.00 | buy |
| Prosight Management, LP | 0 | 130,000 | +130,000 | 0.00 | 0.68 | +0.68 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 400,000 | 528,937 | +128,937 | 0.03 | 0.02 | -0.01 | buy |
| NORTHERN TRUST CORP | 25,775 | 91,864 | +66,089 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 28,843 | 93,643 | +64,800 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 63,059 | 127,787 | +64,728 | 0.03 | 0.02 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 64,366 | +64,366 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 584,989 | 645,650 | +60,661 | 0.00 | 0.00 | -0.00 | buy |
| Velan Capital Investment Management LP | 0 | 50,000 | +50,000 | 0.00 | 1.12 | +1.12 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 42,970 | +42,970 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 39,516 | +39,516 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 38,793 | 75,292 | +36,499 | 0.64 | 0.54 | -0.11 | buy |
| Atle Fund Management AB | 39,100 | 69,573 | +30,473 | 1.08 | 0.67 | -0.40 | buy |
| Artia Global Partners LP | 20,000 | 47,400 | +27,400 | 0.23 | 0.28 | +0.04 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 26,000 | +26,000 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 5,838 | 30,810 | +24,972 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 24,564 | +24,564 | 0.00 | 0.00 | +0.00 | buy |
| WEXFORD CAPITAL LP | 44,156 | 68,556 | +24,400 | 0.51 | 0.34 | -0.17 | buy |
| Squarepoint Ops LLC | 0 | 24,063 | +24,063 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 23,801 | +23,801 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 302,186 | 325,668 | +23,482 | 0.00 | 0.00 | -0.00 | buy |
| Aberdeen Group plc | 5,143 | 26,894 | +21,751 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 19,073 | +19,073 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 231,057 | 249,759 | +18,702 | 0.00 | 0.00 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 18,372 | +18,372 | 0.00 | 0.02 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 16,000 | +16,000 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 14,886 | +14,886 | 0.00 | 0.01 | +0.01 | buy |
| Qube Research & Technologies Ltd | 746 | 15,321 | +14,575 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 686 | 12,852 | +12,166 | 0.00 | 0.01 | +0.01 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 0 | 11,383 | +11,383 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 23,212 | 34,039 | +10,827 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 0 | 7,331 | +7,331 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 5,951 | +5,951 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 19,060 | 24,760 | +5,700 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 5,507 | +5,507 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 5,408 | +5,408 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 4,383 | 7,484 | +3,101 | 0.00 | 0.00 | -0.00 | buy |
| Vestcor Inc | 0 | 3,100 | +3,100 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 140,300 | 143,356 | +3,056 | 0.05 | 0.02 | -0.03 | buy |
| ALLIANCEBERNSTEIN L.P. | 7,210 | 9,920 | +2,710 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 21,649 | 24,215 | +2,566 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 7,542 | 10,028 | +2,486 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 21,131 | 22,731 | +1,600 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 4,174 | 5,590 | +1,416 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 23 | 1,071 | +1,048 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 40,800 | 41,800 | +1,000 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 14,103 | 14,691 | +588 | 0.00 | 0.00 | -0.00 | buy |
| Quarry LP | 400 | 750 | +350 | 0.01 | 0.00 | -0.00 | buy |
| Venturi Wealth Management, LLC | 0 | 89 | +89 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 76 | +76 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 1,028 | 1,103 | +75 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 63 | +63 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 5,467 | 5,527 | +60 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 29 | +29 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 736 | 757 | +21 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| Jaffetilchin Investment Partners, LLC | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 6,568 | 6,576 | +8 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| EARNED WEALTH ADVISORS, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 996 | 996 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CIBC Private Wealth Group LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 45,364 | 45,364 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Vivo Capital, LLC | 166,794 | 166,794 | 0 | 0.70 | 0.28 | -0.41 | hold |
| BFSG, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HighMark Wealth Management LLC | 41 | 41 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fortis Group Advisors, LLC | 14 | 14 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JTC Employer Solutions Trustee Ltd | 1,106 | 1,106 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STUDIO INVESTMENT MANAGEMENT LLC | 9 | 9 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 16,075 | 16,075 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 4,100 | 4,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| COMERICA BANK | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 352 | 352 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Scarborough Advisors, LLC | 6 | 0 | -6 | 0.00 | 0.00 | -0.00 | sell |
| CoreCap Advisors, LLC | 25 | 0 | -25 | 0.00 | 0.00 | -0.00 | sell |
| NBC SECURITIES, INC. | 33 | 0 | -33 | 0.00 | 0.00 | -0.00 | sell |
| Pacer Advisors, Inc. | 132 | 0 | -132 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 4,633 | 4,249 | -384 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 11,414 | 10,382 | -1,032 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 1,727 | 0 | -1,727 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 86,349 | 82,618 | -3,731 | 0.12 | 0.05 | -0.07 | sell |
| Invesco Ltd. | 4,784 | 0 | -4,784 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 30,236 | 24,276 | -5,960 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 12,000 | 4,000 | -8,000 | 0.11 | 0.01 | -0.10 | sell |
| Cambridge Investment Research Advisors, Inc. | 8,682 | 0 | -8,682 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 10,292 | 0 | -10,292 | 0.00 | 0.00 | -0.00 | sell |
| NEOS Investment Management LLC | 36,455 | 25,486 | -10,969 | 0.07 | 0.02 | -0.05 | sell |
| GOLDMAN SACHS GROUP INC | 60,528 | 49,420 | -11,108 | 0.00 | 0.00 | -0.00 | sell |
| GILDER GAGNON HOWE & CO LLC | 11,328 | 0 | -11,328 | 0.01 | 0.00 | -0.01 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 15,854 | 4,283 | -11,571 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 12,272 | 0 | -12,272 | 0.01 | 0.00 | -0.01 | sell |
| Informed Momentum Co LLC | 12,609 | 0 | -12,609 | 0.09 | 0.00 | -0.09 | sell |