| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 24,424,865 | 33,722,974 | +9,298,109 | 5.21 | 6.96 | +1.75 | buy |
| APEIRON CAPITAL Ltd | 0 | 1,200,941 | +1,200,941 | 0.00 | 21.87 | +21.87 | buy |
| Polar Capital Holdings Plc | 0 | 1,000,000 | +1,000,000 | 0.00 | 0.11 | +0.11 | buy |
| UBS Group AG | 1,264,223 | 2,093,958 | +829,735 | 0.01 | 0.01 | +0.00 | buy |
| Fiera Capital Corp | 0 | 782,847 | +782,847 | 0.00 | 0.06 | +0.06 | buy |
| Polymer Capital Management (HK) LTD | 396,175 | 890,029 | +493,854 | 1.33 | 2.97 | +1.64 | buy |
| ROCKLAND TRUST CO | 0 | 400,000 | +400,000 | 0.00 | 0.41 | +0.41 | buy |
| NORGES BANK | 1,017,974 | 1,389,862 | +371,888 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 291,222 | +291,222 | 0.00 | 0.01 | +0.01 | buy |
| MARSHALL WACE, LLP | 0 | 271,641 | +271,641 | 0.00 | 0.01 | +0.01 | buy |
| Caption Management, LLC | 0 | 267,255 | +267,255 | 0.00 | 0.52 | +0.52 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 250,000 | +250,000 | 0.00 | 0.27 | +0.27 | buy |
| HRT FINANCIAL LP | 0 | 241,685 | +241,685 | 0.00 | 0.02 | +0.02 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 227,860 | +227,860 | 0.00 | 0.20 | +0.20 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 29,377 | 256,890 | +227,513 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 369,222 | 566,147 | +196,925 | 0.00 | 0.00 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 191,119 | +191,119 | 0.00 | 0.09 | +0.09 | buy |
| Woodline Partners LP | 0 | 182,012 | +182,012 | 0.00 | 0.02 | +0.02 | buy |
| Verition Fund Management LLC | 0 | 181,983 | +181,983 | 0.00 | 0.02 | +0.02 | buy |
| MORGAN STANLEY | 478,126 | 642,001 | +163,875 | 0.00 | 0.00 | +0.00 | buy |
| BI Asset Management Fondsmaeglerselskab A/S | 0 | 125,100 | +125,100 | 0.00 | 0.03 | +0.03 | buy |
| WELLS FARGO & COMPANY/MN | 126,270 | 234,720 | +108,450 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 29,779 | 137,445 | +107,666 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 104,660 | +104,660 | 0.00 | 0.02 | +0.02 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 94,550 | +94,550 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 286,029 | 380,004 | +93,975 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 87,943 | +87,943 | 0.00 | 0.03 | +0.03 | buy |
| Engineers Gate Manager LP | 0 | 87,830 | +87,830 | 0.00 | 0.02 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 86,889 | +86,889 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 86,494 | +86,494 | 0.00 | 0.00 | +0.00 | buy |
| Rhenman & Partners Asset Management AB | 0 | 78,000 | +78,000 | 0.00 | 0.21 | +0.21 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 66,969 | +66,969 | 0.00 | 0.11 | +0.11 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 33,070 | 97,502 | +64,432 | 0.00 | 0.00 | +0.00 | buy |
| Granahan Investment Management, LLC | 124,527 | 185,640 | +61,113 | 0.12 | 0.16 | +0.04 | buy |
| BARCLAYS PLC | 255,612 | 313,824 | +58,212 | 0.00 | 0.00 | +0.00 | buy |
| Treasurer of the State of North Carolina | 0 | 54,560 | +54,560 | 0.00 | 0.00 | +0.00 | buy |
| Perseverance Asset Management International | 91,359 | 139,928 | +48,569 | 0.23 | 0.75 | +0.52 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 253,499 | 299,973 | +46,474 | 0.01 | 0.01 | +0.00 | buy |
| Polar Asset Management Partners Inc. | 12,444 | 58,400 | +45,956 | 0.01 | 0.03 | +0.02 | buy |
| NOMURA HOLDINGS INC | 0 | 43,956 | +43,956 | 0.00 | 0.01 | +0.01 | buy |
| XTX Topco Ltd | 0 | 43,448 | +43,448 | 0.00 | 0.04 | +0.04 | buy |
| FRANKLIN RESOURCES INC | 97,390 | 139,146 | +41,756 | 0.00 | 0.00 | +0.00 | buy |
| Neo Ivy Capital Management | 0 | 40,169 | +40,169 | 0.00 | 0.27 | +0.27 | buy |
| STRS OHIO | 0 | 36,899 | +36,899 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 36,265 | +36,265 | 0.00 | 0.00 | +0.00 | buy |
| Quantessence Capital LLC | 0 | 36,187 | +36,187 | 0.00 | 0.23 | +0.23 | buy |
| Invesco Ltd. | 389,705 | 424,027 | +34,322 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 215,939 | 249,710 | +33,771 | 0.01 | 0.01 | +0.00 | buy |
| INCEPTIONR LLC | 0 | 33,096 | +33,096 | 0.00 | 0.16 | +0.16 | buy |
| STIFEL FINANCIAL CORP | 0 | 32,339 | +32,339 | 0.00 | 0.00 | +0.00 | buy |
| ASSETMARK, INC | 0 | 31,084 | +31,084 | 0.00 | 0.00 | +0.00 | buy |
| Illinois Municipal Retirement Fund | 0 | 31,062 | +31,062 | 0.00 | 0.01 | +0.01 | buy |
| Cambridge Investment Research Advisors, Inc. | 0 | 30,820 | +30,820 | 0.00 | 0.00 | +0.00 | buy |
| Orion Porfolio Solutions, LLC | 22,970 | 52,964 | +29,994 | 0.00 | 0.01 | +0.01 | buy |
| LPL Financial LLC | 13,460 | 40,005 | +26,545 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 26,303 | +26,303 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 20,425 | 44,588 | +24,163 | 0.00 | 0.01 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 22,300 | +22,300 | 0.00 | 0.13 | +0.13 | buy |
| Man Group plc | 19,005 | 40,407 | +21,402 | 0.00 | 0.00 | +0.00 | buy |
| Cynosure Group, LLC | 0 | 18,609 | +18,609 | 0.00 | 0.04 | +0.04 | buy |
| XPONANCE, INC. | 0 | 16,636 | +16,636 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 1,918 | 17,802 | +15,884 | 0.01 | 0.05 | +0.04 | buy |
| Snowden Capital Advisors LLC | 0 | 14,915 | +14,915 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 13,149 | +13,149 | 0.00 | 0.03 | +0.03 | buy |
| ADAR1 Capital Management, LLC | 0 | 12,000 | +12,000 | 0.00 | 0.04 | +0.04 | buy |
| Mariner, LLC | 0 | 11,762 | +11,762 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 11,692 | +11,692 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 11,535 | +11,535 | 0.00 | 0.08 | +0.08 | buy |
| Jump Financial, LLC | 0 | 11,452 | +11,452 | 0.00 | 0.00 | +0.00 | buy |
| Amundi | 0 | 11,407 | +11,407 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT SECURITIES GROUP LLC | 0 | 10,602 | +10,602 | 0.00 | 0.08 | +0.08 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 10,578 | +10,578 | 0.00 | 0.00 | +0.00 | buy |
| Arista Wealth Management, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.03 | +0.03 | buy |
| NEOS Investment Management LLC | 98,111 | 106,943 | +8,832 | 0.04 | 0.03 | -0.01 | buy |
| TEMA ETFS LLC | 98,111 | 106,943 | +8,832 | 0.57 | 0.60 | +0.04 | buy |
| Tower Research Capital LLC (TRC) | 9,275 | 16,044 | +6,769 | 0.01 | 0.01 | +0.00 | buy |
| Legal & General Group Plc | 19,705 | 26,367 | +6,662 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 0 | 6,207 | +6,207 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 3,185 | 7,943 | +4,758 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 7,976 | 12,466 | +4,490 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 100 | 4,364 | +4,264 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 26,518 | 30,548 | +4,030 | 0.00 | 0.00 | +0.00 | buy |
| Sovran Advisors, LLC | 146,528 | 150,047 | +3,519 | 0.47 | 0.36 | -0.11 | buy |
| AlphaQuest LLC | 2,542 | 5,891 | +3,349 | 0.01 | 0.01 | +0.01 | buy |
| Q3 Asset Management | 16,473 | 19,567 | +3,094 | 0.22 | 0.15 | -0.07 | buy |
| FLORIDA FINANCIAL ADVISORS, LLC | 12,945 | 15,921 | +2,976 | 0.10 | 0.11 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4,540 | 7,368 | +2,828 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 340,775 | 343,524 | +2,749 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 0 | 2,638 | +2,638 | 0.00 | 0.00 | +0.00 | buy |
| GRIFFIN ASSET MANAGEMENT, INC. | 117,210 | 119,382 | +2,172 | 0.28 | 0.30 | +0.02 | buy |
| Focus Partners Wealth | 84,475 | 86,440 | +1,965 | 0.00 | 0.00 | -0.00 | buy |
| Ball & Co Wealth Management Inc. | 0 | 1,500 | +1,500 | 0.00 | 0.03 | +0.03 | buy |
| Creative Planning | 20,054 | 21,390 | +1,336 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 15,651 | 16,963 | +1,312 | 0.03 | 0.03 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 147,966 | 149,162 | +1,196 | 0.27 | 0.30 | +0.03 | buy |
| Cerity Partners LLC | 113,654 | 114,844 | +1,190 | 0.00 | 0.00 | -0.00 | buy |
| DIADEMA PARTNERS LP | 0 | 932 | +932 | 0.00 | 0.01 | +0.01 | buy |
| CROWLEY WEALTH MANAGEMENT, INC. | 0 | 900 | +900 | 0.00 | 0.02 | +0.02 | buy |
| COMERICA BANK | 22 | 883 | +861 | 0.00 | 0.00 | +0.00 | buy |
| First Horizon Advisors, Inc. | 0 | 785 | +785 | 0.00 | 0.00 | +0.00 | buy |