| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 24,272,798 | 34,009,994 | +9,737,196 | 0.00 | 0.00 | +0.00 | buy |
| ARK Investment Management LLC | 32,769,186 | 32,346,398 | -422,788 | 1.97 | 1.82 | -0.15 | sell |
| BAILLIE GIFFORD & CO | 25,239,870 | 24,864,058 | -375,812 | 0.12 | 0.13 | +0.00 | sell |
| BlackRock, Inc. | 20,742,797 | 23,436,636 | +2,693,839 | 0.00 | 0.00 | +0.00 | buy |
| SOFTBANK GROUP CORP. | 0 | 14,667,491 | +14,667,491 | 0.00 | 0.42 | +0.42 | buy |
| Mubadala Investment Co PJSC | 12,985,927 | 12,985,927 | 0 | 0.45 | 0.43 | -0.03 | hold |
| STATE STREET CORP | 12,870,272 | 12,578,360 | -291,912 | 0.00 | 0.00 | -0.00 | sell |
| Kinnevik AB (publ) | 11,905,668 | 11,905,668 | 0 | 100.00 | 100.00 | 0.00 | hold |
| Novo Holdings A/S | 0 | 10,114,633 | +10,114,633 | 0.00 | 4.14 | +4.14 | buy |
| MIC Capital Management UK LLP | 8,451,758 | 9,644,033 | +1,192,275 | 7.73 | 9.23 | +1.50 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 9,766,728 | 8,980,601 | -786,127 | 0.04 | 0.04 | -0.00 | sell |
| Nikko Asset Management Americas, Inc. | 9,694,778 | 8,908,651 | -786,127 | 0.72 | 0.65 | -0.07 | sell |
| RA CAPITAL MANAGEMENT, L.P. | 15,384,615 | 7,725,096 | -7,659,519 | 1.17 | 0.69 | -0.47 | sell |
| NVIDIA CORP | 7,706,363 | 7,706,363 | 0 | 11.73 | 17.11 | +5.38 | hold |
| FMR LLC | 8,363,530 | 7,072,181 | -1,291,349 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 5,431,911 | 6,087,149 | +655,238 | 0.00 | 0.00 | +0.00 | buy |
| Data Collective IV GP, LLC | 5,941,120 | 5,941,120 | 0 | 23.95 | 17.75 | -6.20 | hold |
| DCVC Opportunity Fund II GP, LLC | 3,951,141 | 3,951,141 | 0 | 26.74 | 23.64 | -3.10 | hold |
| Lingotto Investment Management LLP | 3,675,077 | 3,675,077 | 0 | 0.70 | 0.67 | -0.03 | hold |
| NORGES BANK | 3,572,556 | 3,465,875 | -106,681 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 799,860 | 3,004,645 | +2,204,785 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 1,877,201 | 2,860,527 | +983,326 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 234,223 | 2,739,247 | +2,505,024 | 0.00 | 0.02 | +0.02 | buy |
| Laurion Capital Management LP | 0 | 2,457,189 | +2,457,189 | 0.00 | 1.03 | +1.03 | buy |
| NORTHERN TRUST CORP | 2,022,625 | 2,394,511 | +371,886 | 0.00 | 0.00 | +0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 2,315,000 | 2,315,000 | 0 | 0.23 | 0.30 | +0.07 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,940,680 | 2,274,003 | +333,323 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 2,140,750 | 2,259,178 | +118,428 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,539,704 | 2,065,208 | +525,504 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,717,779 | 1,708,040 | -9,739 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,069,599 | 1,666,989 | +597,390 | 0.01 | 0.02 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 1,597,298 | 1,660,509 | +63,211 | 0.02 | 0.03 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,176,191 | 1,057,167 | -119,024 | 0.00 | 0.00 | -0.00 | sell |
| Comprehensive Financial Management LLC | 941,895 | 941,895 | 0 | 0.17 | 0.18 | +0.00 | hold |
| Liontrust Investment Partners LLP | 990,000 | 931,727 | -58,273 | 0.11 | 0.09 | -0.01 | sell |
| BANK OF AMERICA CORP /DE/ | 1,165,425 | 882,864 | -282,561 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 926,118 | 850,636 | -75,482 | 0.00 | 0.00 | -0.00 | sell |
| Vestmark Advisory Solutions, Inc. | 732,933 | 845,154 | +112,221 | 0.18 | 0.22 | +0.04 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 186,082 | 733,011 | +546,929 | 0.06 | 0.29 | +0.24 | buy |
| Woodline Partners LP | 671,319 | 670,867 | -452 | 0.04 | 0.03 | -0.01 | sell |
| Nan Fung Group Holdings Ltd | 0 | 664,610 | +664,610 | 0.00 | 3.84 | +3.84 | buy |
| BARCLAYS PLC | 697,432 | 633,125 | -64,307 | 0.00 | 0.00 | +0.00 | sell |
| Pivotal bioVenture Partners Investment Advisor LLC | 0 | 595,518 | +595,518 | 0.00 | 2.72 | +2.72 | buy |
| Rafferty Asset Management, LLC | 675,791 | 595,472 | -80,319 | 0.02 | 0.01 | -0.00 | sell |
| Institute for Wealth Management, LLC. | 0 | 580,997 | +580,997 | 0.00 | 0.49 | +0.49 | buy |
| LAZARD ASSET MANAGEMENT LLC | 642,308 | 555,850 | -86,458 | 0.01 | 0.01 | -0.00 | sell |
| CITIGROUP INC | 190,752 | 500,988 | +310,236 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 357,100 | 486,700 | +129,600 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 115,017 | 458,321 | +343,304 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 489,900 | 451,745 | -38,155 | 0.01 | 0.01 | -0.00 | sell |
| Ensign Peak Advisors, Inc | 408,986 | 410,286 | +1,300 | 0.00 | 0.00 | +0.00 | buy |
| Bellevue Group AG | 392,881 | 377,806 | -15,075 | 0.04 | 0.05 | +0.01 | sell |
| LPL Financial LLC | 360,438 | 367,785 | +7,347 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 238,033 | 352,855 | +114,822 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 310,468 | 334,032 | +23,564 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 66,639 | 281,922 | +215,283 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 190,175 | 281,704 | +91,529 | 0.05 | 0.06 | +0.02 | buy |
| SIMPLEX TRADING, LLC | 284,713 | 263,372 | -21,341 | 0.06 | 0.05 | -0.01 | sell |
| Legal & General Group Plc | 185,473 | 253,426 | +67,953 | 0.00 | 0.00 | +0.00 | buy |
| Carroll Investors, Inc | 162,740 | 246,985 | +84,245 | 0.70 | 0.94 | +0.24 | buy |
| ALLIANCEBERNSTEIN L.P. | 217,294 | 243,214 | +25,920 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 281,467 | 242,190 | -39,277 | 0.00 | 0.00 | -0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 220,110 | 231,756 | +11,646 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 177,086 | 231,535 | +54,449 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 141,729 | 217,723 | +75,994 | 0.00 | 0.00 | +0.00 | buy |
| ALLEN OPERATIONS LLC | 217,657 | 217,657 | 0 | 0.24 | 0.23 | -0.01 | hold |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 82,352 | 200,470 | +118,118 | 0.06 | 0.16 | +0.10 | buy |
| Russell Investments Group, Ltd. | 238,098 | 196,652 | -41,446 | 0.00 | 0.00 | -0.00 | sell |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 187,927 | 187,927 | 0 | 0.01 | 0.01 | +0.00 | hold |
| CAPITAL FUND MANAGEMENT S.A. | 0 | 183,796 | +183,796 | 0.00 | 0.01 | +0.01 | buy |
| Invesco Ltd. | 115,551 | 178,619 | +63,068 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 92,329 | 170,655 | +78,326 | 0.00 | 0.00 | +0.00 | buy |
| Casdin Capital, LLC | 0 | 165,323 | +165,323 | 0.00 | 0.07 | +0.07 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 157,123 | 165,062 | +7,939 | 0.00 | 0.00 | +0.00 | buy |
| PIER 88 INVESTMENT PARTNERS LLC | 133,910 | 161,730 | +27,820 | 0.19 | 0.22 | +0.02 | buy |
| STIFEL FINANCIAL CORP | 161,978 | 159,887 | -2,091 | 0.00 | 0.00 | +0.00 | sell |
| BENJAMIN EDWARDS INC | 162,481 | 158,994 | -3,487 | 0.02 | 0.02 | -0.00 | sell |
| MetLife Investment Management, LLC | 136,541 | 149,808 | +13,267 | 0.01 | 0.01 | +0.00 | buy |
| MARATHON CAPITAL MANAGEMENT | 181,845 | 146,395 | -35,450 | 0.29 | 0.25 | -0.04 | sell |
| GUGGENHEIM CAPITAL LLC | 155,230 | 143,057 | -12,173 | 0.01 | 0.01 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 112,438 | 131,990 | +19,552 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 130,443 | +130,443 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 124,654 | 124,714 | +60 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 127,494 | 123,705 | -3,789 | 0.00 | 0.00 | +0.00 | sell |
| HighTower Advisors, LLC | 24,144 | 122,770 | +98,626 | 0.00 | 0.00 | +0.00 | buy |
| Privium Fund Management B.V. | 78,000 | 119,000 | +41,000 | 0.13 | 0.18 | +0.05 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 105,018 | 114,945 | +9,927 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 132,811 | 114,886 | -17,925 | 0.03 | 0.03 | -0.00 | sell |
| WESBANCO BANK INC | 111,200 | 112,517 | +1,317 | 0.02 | 0.03 | +0.00 | buy |
| Mariner, LLC | 83,564 | 111,063 | +27,499 | 0.00 | 0.00 | +0.00 | buy |
| COMMONS CAPITAL, LLC | 115,959 | 108,520 | -7,439 | 0.84 | 0.67 | -0.18 | sell |
| Caption Management, LLC | 0 | 102,900 | +102,900 | 0.00 | 0.03 | +0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 52,953 | 93,409 | +40,456 | 0.00 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 62,636 | 91,670 | +29,034 | 0.00 | 0.00 | +0.00 | buy |
| Values First Advisors, Inc. | 60,223 | 89,775 | +29,552 | 0.22 | 0.33 | +0.12 | buy |
| Headlands Technologies LLC | 30,103 | 89,314 | +59,211 | 0.02 | 0.06 | +0.04 | buy |
| ProShare Advisors LLC | 61,311 | 88,158 | +26,847 | 0.00 | 0.00 | +0.00 | buy |
| Cambridge Investment Research Advisors, Inc. | 79,583 | 87,984 | +8,401 | 0.00 | 0.00 | +0.00 | buy |
| Plancorp, LLC | 77,584 | 87,584 | +10,000 | 0.02 | 0.02 | +0.00 | buy |
| DnB Asset Management AS | 0 | 85,365 | +85,365 | 0.00 | 0.00 | +0.00 | buy |