| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 10,162,632 | 9,999,107 | -163,525 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 9,821,897 | 5,790,051 | -4,031,846 | 0.01 | 0.01 | -0.01 | sell |
| BlackRock, Inc. | 5,437,508 | 5,596,166 | +158,658 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 3,775,691 | 4,513,832 | +738,141 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 3,247,694 | 3,729,117 | +481,423 | 0.01 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 2,639,055 | 2,577,087 | -61,968 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,066,651 | 2,099,564 | +32,913 | 0.08 | 0.08 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,476,314 | 2,092,840 | +616,526 | 0.01 | 0.01 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 1,313,783 | 2,085,487 | +771,704 | 0.06 | 0.08 | +0.02 | buy |
| CITADEL ADVISORS LLC | 872,975 | 1,898,342 | +1,025,367 | 0.02 | 0.04 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,923,305 | 1,608,606 | -314,699 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 1,091,428 | 1,555,128 | +463,700 | 0.06 | 0.08 | +0.02 | buy |
| UBS Group AG | 951,527 | 1,342,308 | +390,781 | 0.01 | 0.01 | +0.00 | buy |
| Pictet Asset Management Holding SA | 1,916,874 | 1,196,305 | -720,569 | 0.05 | 0.03 | -0.02 | sell |
| RAYMOND JAMES FINANCIAL INC | 822,278 | 954,272 | +131,994 | 0.01 | 0.01 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 370,000 | 870,000 | +500,000 | 0.50 | 0.88 | +0.38 | buy |
| JANE STREET GROUP, LLC | 732,174 | 793,806 | +61,632 | 0.03 | 0.02 | -0.01 | buy |
| BRAIDWELL LP | 1,437,555 | 759,455 | -678,100 | 1.30 | 0.59 | -0.71 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 727,420 | 697,708 | -29,712 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 611,697 | 648,295 | +36,598 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 524,772 | 578,268 | +53,496 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 543,064 | 557,269 | +14,205 | 0.00 | 0.00 | -0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 447,217 | 544,201 | +96,984 | 0.04 | 0.05 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 565,066 | 514,002 | -51,064 | 0.01 | 0.01 | -0.00 | sell |
| BlackBarn Capital Partners LP | 350,000 | 500,000 | +150,000 | 3.07 | 4.29 | +1.21 | buy |
| Bank of New York Mellon Corp | 442,675 | 499,786 | +57,111 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 236,070 | 471,259 | +235,189 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 231,200 | 460,807 | +229,607 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 631,353 | 444,210 | -187,143 | 0.01 | 0.01 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 941,937 | 427,695 | -514,242 | 0.02 | 0.01 | -0.01 | sell |
| CITIGROUP INC | 864,111 | 414,603 | -449,508 | 0.02 | 0.01 | -0.01 | sell |
| Quinn Opportunity Partners LLC | 267,772 | 403,445 | +135,673 | 0.61 | 0.77 | +0.16 | buy |
| BAKER BROS. ADVISORS LP | 0 | 366,083 | +366,083 | 0.00 | 0.07 | +0.07 | buy |
| BLAIR WILLIAM & CO/IL | 330,007 | 355,926 | +25,919 | 0.02 | 0.02 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 376,448 | 350,367 | -26,081 | 0.01 | 0.01 | -0.00 | sell |
| MACQUARIE GROUP LTD | 330,100 | 330,100 | 0 | 0.01 | 0.01 | -0.00 | hold |
| WELLS FARGO & COMPANY/MN | 177,068 | 312,520 | +135,452 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 270,409 | 308,230 | +37,821 | 0.06 | 0.05 | -0.01 | buy |
| Woodline Partners LP | 301,197 | 301,994 | +797 | 0.04 | 0.04 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 298,984 | 296,193 | -2,791 | 0.00 | 0.00 | -0.00 | sell |
| Fiera Capital Corp | 279,243 | 272,956 | -6,287 | 0.03 | 0.02 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 153,418 | 267,744 | +114,326 | 0.00 | 0.00 | +0.00 | buy |
| First Washington CORP | 106,482 | 266,843 | +160,361 | 0.91 | 1.88 | +0.97 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 244,459 | +244,459 | 0.00 | 0.04 | +0.04 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 509,094 | 243,766 | -265,328 | 0.00 | 0.00 | -0.00 | sell |
| 683 Capital Management, LLC | 254,000 | 240,000 | -14,000 | 0.68 | 0.57 | -0.11 | sell |
| Rhenman & Partners Asset Management AB | 85,000 | 216,288 | +131,288 | 0.28 | 0.63 | +0.34 | buy |
| Swiss National Bank | 203,700 | 206,800 | +3,100 | 0.00 | 0.00 | -0.00 | buy |
| ExodusPoint Capital Management, LP | 38,716 | 204,190 | +165,474 | 0.01 | 0.08 | +0.06 | buy |
| Rafferty Asset Management, LLC | 157,499 | 199,387 | +41,888 | 0.01 | 0.02 | +0.00 | buy |
| LPL Financial LLC | 138,371 | 196,507 | +58,136 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 90,930 | 195,707 | +104,777 | 0.01 | 0.02 | +0.01 | buy |
| Nuveen, LLC | 191,890 | 195,158 | +3,268 | 0.00 | 0.00 | -0.00 | buy |
| DIADEMA PARTNERS LP | 197,468 | 193,689 | -3,779 | 3.25 | 3.55 | +0.29 | sell |
| Granahan Investment Management, LLC | 305,091 | 189,529 | -115,562 | 0.33 | 0.20 | -0.13 | sell |
| Cetera Investment Advisers | 157,638 | 188,471 | +30,833 | 0.01 | 0.01 | -0.00 | buy |
| OPPENHEIMER & CO INC | 158,228 | 184,314 | +26,086 | 0.06 | 0.06 | +0.00 | buy |
| PFM Health Sciences, LP | 37,729 | 183,538 | +145,809 | 0.09 | 0.41 | +0.32 | buy |
| ADAR1 Capital Management, LLC | 67,813 | 175,919 | +108,106 | 0.29 | 0.46 | +0.17 | buy |
| Gotham Asset Management, LLC | 0 | 169,683 | +169,683 | 0.00 | 0.02 | +0.02 | buy |
| Walleye Trading LLC | 34,428 | 162,482 | +128,054 | 0.02 | 0.07 | +0.05 | buy |
| D. E. Shaw & Co., Inc. | 205,473 | 161,357 | -44,116 | 0.01 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 168,023 | 156,309 | -11,714 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 0 | 154,100 | +154,100 | 0.00 | 0.01 | +0.01 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 319,302 | 146,589 | -172,713 | 0.01 | 0.00 | -0.00 | sell |
| Artia Global Partners LP | 96,479 | 146,179 | +49,700 | 0.66 | 0.68 | +0.02 | buy |
| Trexquant Investment LP | 210,428 | 140,531 | -69,897 | 0.06 | 0.04 | -0.02 | sell |
| WASATCH ADVISORS LP | 262,045 | 128,467 | -133,578 | 0.04 | 0.02 | -0.02 | sell |
| BAMCO INC /NY/ | 126,737 | 126,737 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Bridgewater Associates, LP | 0 | 123,491 | +123,491 | 0.00 | 0.01 | +0.01 | buy |
| RFG Advisory, LLC | 65,039 | 120,214 | +55,175 | 0.04 | 0.07 | +0.02 | buy |
| RHUMBLINE ADVISERS | 114,533 | 113,761 | -772 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 118,898 | 112,698 | -6,200 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 123,348 | 111,641 | -11,707 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 95,954 | 109,297 | +13,343 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 0 | 107,800 | +107,800 | 0.00 | 0.16 | +0.16 | buy |
| PERCEPTIVE ADVISORS LLC | 380,700 | 105,597 | -275,103 | 0.38 | 0.08 | -0.30 | sell |
| Quantum Private Wealth, LLC | 86,716 | 105,016 | +18,300 | 0.74 | 0.81 | +0.06 | buy |
| Institute for Wealth Management, LLC. | 90,377 | 103,447 | +13,070 | 0.27 | 0.28 | +0.02 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 92,823 | 100,987 | +8,164 | 0.00 | 0.00 | -0.00 | buy |
| Kintayl Capital LP | 129,607 | 100,191 | -29,416 | 2.15 | 1.81 | -0.35 | sell |
| SG Americas Securities, LLC | 14,285 | 95,804 | +81,519 | 0.00 | 0.01 | +0.01 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 90,750 | 94,264 | +3,514 | 0.00 | 0.00 | +0.00 | buy |
| U.S. Capital Wealth Advisors, LLC | 63,546 | 94,165 | +30,619 | 0.05 | 0.07 | +0.02 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 78,179 | 85,491 | +7,312 | 0.00 | 0.00 | +0.00 | buy |
| State of New Jersey Common Pension Fund D | 67,921 | 82,894 | +14,973 | 0.01 | 0.01 | +0.00 | buy |
| Midwest Trust Co | 54,217 | 82,847 | +28,630 | 0.02 | 0.03 | +0.01 | buy |
| NJ State Employees Deferred Compensation Plan | 48,000 | 79,320 | +31,320 | 0.15 | 0.23 | +0.08 | buy |
| OSAIC HOLDINGS, INC. | 75,652 | 78,622 | +2,970 | 0.00 | 0.00 | -0.00 | buy |
| Allianz Asset Management GmbH | 72,002 | 76,665 | +4,663 | 0.00 | 0.00 | -0.00 | buy |
| Profit Investment Management, LLC | 116,852 | 76,554 | -40,298 | 2.79 | 2.53 | -0.26 | sell |
| Bellevue Group AG | 0 | 76,082 | +76,082 | 0.00 | 0.04 | +0.04 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 73,259 | 75,051 | +1,792 | 0.00 | 0.00 | +0.00 | buy |
| Qsemble Capital Management, LP | 26,305 | 71,152 | +44,847 | 0.07 | 0.18 | +0.12 | buy |
| WINTON GROUP Ltd | 0 | 68,700 | +68,700 | 0.00 | 0.07 | +0.07 | buy |
| SCOTIA CAPITAL INC. | 42,134 | 67,889 | +25,755 | 0.01 | 0.01 | +0.00 | buy |
| Freestone Capital Holdings, LLC | 0 | 66,417 | +66,417 | 0.00 | 0.05 | +0.05 | buy |
| Dana Investment Advisors, Inc. | 45,389 | 65,984 | +20,595 | 0.04 | 0.05 | +0.01 | buy |
| DAFNA Capital Management LLC | 64,516 | 64,516 | 0 | 0.47 | 0.42 | -0.05 | hold |
| Cubist Systematic Strategies, LLC | 596,650 | 64,355 | -532,295 | 0.17 | 0.02 | -0.15 | sell |