| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 3,550,848 | 3,549,554 | -1,294 | 0.01 | 0.00 | -0.00 | sell |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,505,872 | 2,703,238 | +1,197,366 | 1.78 | 1.64 | -0.14 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 2,211,091 | 2,535,954 | +324,863 | 0.04 | 0.02 | -0.01 | buy |
| MORGAN STANLEY | 1,259,762 | 1,450,634 | +190,872 | 0.01 | 0.00 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 1,212,162 | 1,188,537 | -23,625 | 0.08 | 0.05 | -0.04 | sell |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,161,285 | 1,137,384 | -23,901 | 0.30 | 0.19 | -0.10 | sell |
| STATE STREET CORP | 918,504 | 956,011 | +37,507 | 0.00 | 0.00 | -0.00 | buy |
| Artisan Partners Limited Partnership | 785,742 | 780,575 | -5,167 | 0.11 | 0.07 | -0.05 | sell |
| BRAIDWELL LP | 540,890 | 677,570 | +136,680 | 1.60 | 1.17 | -0.43 | buy |
| GOLDMAN SACHS GROUP INC | 284,885 | 664,003 | +379,118 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 411,329 | 638,928 | +227,599 | 0.01 | 0.01 | -0.00 | buy |
| Soleus Capital Management, L.P. | 299,399 | 576,299 | +276,900 | 1.17 | 1.20 | +0.03 | buy |
| Vestal Point Capital, LP | 0 | 539,269 | +539,269 | 0.00 | 0.78 | +0.78 | buy |
| Assenagon Asset Management S.A. | 264,999 | 520,174 | +255,175 | 0.04 | 0.04 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 516,816 | 513,175 | -3,641 | 0.02 | 0.01 | -0.01 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 491,750 | 510,234 | +18,484 | 0.00 | 0.00 | -0.00 | buy |
| Aberdeen Group plc | 460,901 | 477,476 | +16,575 | 0.07 | 0.04 | -0.03 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 410,768 | 469,968 | +59,200 | 0.06 | 0.04 | -0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 463,316 | 448,787 | -14,529 | 0.01 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 15,000 | 405,197 | +390,197 | 0.10 | 1.26 | +1.15 | buy |
| CITADEL ADVISORS LLC | 511,318 | 394,076 | -117,242 | 0.03 | 0.01 | -0.02 | sell |
| MILLENNIUM MANAGEMENT LLC | 202,140 | 386,146 | +184,006 | 0.01 | 0.01 | +0.00 | buy |
| Walleye Capital LLC | 78,217 | 358,489 | +280,272 | 0.04 | 0.11 | +0.07 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 141,964 | 325,663 | +183,699 | 0.13 | 0.18 | +0.04 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 454,810 | 319,758 | -135,052 | 0.03 | 0.01 | -0.02 | sell |
| AQR CAPITAL MANAGEMENT LLC | 27,040 | 308,662 | +281,622 | 0.00 | 0.01 | +0.01 | buy |
| Jefferies Financial Group Inc. | 307,588 | 306,423 | -1,165 | 0.23 | 0.19 | -0.04 | sell |
| BAMCO INC /NY/ | 337,486 | 298,470 | -39,016 | 0.08 | 0.05 | -0.04 | sell |
| Amundi | 364,622 | 256,830 | -107,792 | 0.01 | 0.00 | -0.01 | sell |
| ROYAL BANK OF CANADA | 10,984 | 252,971 | +241,987 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 341,397 | 234,670 | -106,727 | 0.01 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 48,497 | 210,573 | +162,076 | 0.01 | 0.01 | +0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 23,415 | 209,486 | +186,071 | 0.00 | 0.02 | +0.01 | buy |
| NORTHERN TRUST CORP | 197,456 | 197,033 | -423 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 210,126 | 186,069 | -24,057 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 194,155 | 183,351 | -10,804 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 0 | 181,426 | +181,426 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 308,171 | 181,313 | -126,858 | 0.00 | 0.00 | -0.00 | sell |
| Bridgewater Associates, LP | 71,727 | 173,533 | +101,806 | 0.02 | 0.04 | +0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 112,873 | 167,218 | +54,345 | 0.06 | 0.05 | -0.01 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 105,500 | 164,100 | +58,600 | 0.01 | 0.01 | -0.00 | buy |
| Champlain Investment Partners, LLC | 203,098 | 158,989 | -44,109 | 0.19 | 0.10 | -0.09 | sell |
| Y-Intercept (Hong Kong) Ltd | 70,635 | 158,274 | +87,639 | 0.15 | 0.15 | +0.01 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 187,226 | 151,856 | -35,370 | 0.03 | 0.02 | -0.02 | sell |
| Bank of New York Mellon Corp | 215,780 | 148,764 | -67,016 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 91,277 | 143,451 | +52,174 | 0.00 | 0.00 | -0.00 | buy |
| Longaeva Partners L.P. | 0 | 138,761 | +138,761 | 0.00 | 0.34 | +0.34 | buy |
| WASATCH ADVISORS LP | 116,068 | 138,603 | +22,535 | 0.06 | 0.05 | -0.02 | buy |
| Regal Partners Ltd | 211,304 | 135,767 | -75,537 | 1.12 | 0.38 | -0.74 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 141 | 132,954 | +132,813 | 0.00 | 0.03 | +0.03 | buy |
| Rock Springs Capital Management LP | 131,000 | 131,800 | +800 | 0.62 | 0.40 | -0.22 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 125,519 | 126,788 | +1,269 | 0.01 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 213,249 | 121,490 | -91,759 | 0.18 | 0.05 | -0.13 | sell |
| Rheos Capital Works Inc. | 117,400 | 117,400 | 0 | 0.69 | 0.40 | -0.29 | hold |
| CAPITAL FUND MANAGEMENT S.A. | 122,706 | 109,015 | -13,691 | 0.11 | 0.05 | -0.06 | sell |
| Susquehanna Portfolio Strategies, LLC | 2,500 | 106,157 | +103,657 | 0.00 | 0.08 | +0.08 | buy |
| SG Americas Securities, LLC | 38,449 | 105,147 | +66,698 | 0.00 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 261,374 | 103,973 | -157,401 | 0.00 | 0.00 | -0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 188,100 | 100,207 | -87,893 | 0.06 | 0.02 | -0.04 | sell |
| Bellevue Group AG | 100,761 | 99,735 | -1,026 | 0.18 | 0.12 | -0.05 | sell |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 91,472 | 93,086 | +1,614 | 0.03 | 0.01 | -0.01 | buy |
| RIVERBRIDGE PARTNERS LLC | 97,111 | 92,494 | -4,617 | 0.17 | 0.12 | -0.05 | sell |
| Gotham Asset Management, LLC | 48,547 | 87,733 | +39,186 | 0.02 | 0.01 | -0.00 | buy |
| Nuveen, LLC | 159,421 | 85,169 | -74,252 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 59,515 | 85,096 | +25,581 | 0.01 | 0.00 | -0.00 | buy |
| BROWN CAPITAL MANAGEMENT LLC | 119,935 | 84,368 | -35,567 | 0.91 | 0.62 | -0.29 | sell |
| Edgestream Partners, L.P. | 17,953 | 82,268 | +64,315 | 0.05 | 0.14 | +0.09 | buy |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 7,204 | 75,239 | +68,035 | 0.00 | 0.01 | +0.01 | buy |
| FIRST TRUST ADVISORS LP | 3,072 | 71,661 | +68,589 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 68,774 | 70,885 | +2,111 | 0.01 | 0.01 | -0.00 | buy |
| RHUMBLINE ADVISERS | 65,894 | 67,907 | +2,013 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 85,655 | 67,641 | -18,014 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 6,822 | 66,814 | +59,992 | 0.00 | 0.01 | +0.01 | buy |
| Qube Research & Technologies Ltd | 0 | 66,184 | +66,184 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 11,322 | 64,260 | +52,938 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 69,756 | 61,583 | -8,173 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF NOVA SCOTIA | 40,042 | 60,000 | +19,958 | 0.01 | 0.01 | -0.00 | buy |
| Swiss National Bank | 55,500 | 55,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Man Group plc | 41,425 | 54,488 | +13,063 | 0.01 | 0.01 | -0.00 | buy |
| JPMORGAN CHASE & CO | 45,388 | 53,615 | +8,227 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 46,250 | 52,860 | +6,610 | 0.07 | 0.04 | -0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 6,220 | 52,702 | +46,482 | 0.01 | 0.03 | +0.02 | buy |
| Bullseye Asset Management LLC | 36,128 | 51,128 | +15,000 | 1.80 | 1.53 | -0.27 | buy |
| FRANKLIN RESOURCES INC | 231,438 | 43,227 | -188,211 | 0.01 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 50,940 | 42,100 | -8,840 | 0.00 | 0.00 | -0.00 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 11,388 | 40,420 | +29,032 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 137,306 | 37,984 | -99,322 | 0.00 | 0.00 | -0.00 | sell |
| Empowered Funds, LLC | 0 | 34,876 | +34,876 | 0.00 | 0.01 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 26,186 | 34,473 | +8,287 | 0.00 | 0.00 | -0.00 | buy |
| Voleon Capital Management LP | 63,627 | 33,122 | -30,505 | 0.13 | 0.04 | -0.09 | sell |
| AXQ CAPITAL, LP | 0 | 33,014 | +33,014 | 0.00 | 0.22 | +0.22 | buy |
| XTX Topco Ltd | 45,783 | 32,483 | -13,300 | 0.11 | 0.03 | -0.08 | sell |
| CITIGROUP INC | 34,672 | 31,606 | -3,066 | 0.00 | 0.00 | -0.00 | sell |
| ZACKS INVESTMENT MANAGEMENT | 0 | 30,021 | +30,021 | 0.00 | 0.01 | +0.01 | buy |
| Engineers Gate Manager LP | 19,204 | 29,567 | +10,363 | 0.02 | 0.02 | -0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 29,990 | 27,519 | -2,471 | 0.00 | 0.00 | -0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 16,453 | 26,566 | +10,113 | 0.00 | 0.00 | -0.00 | buy |
| Quantinno Capital Management LP | 13,048 | 26,555 | +13,507 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 32,549 | 24,871 | -7,678 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 24,947 | 24,180 | -767 | 0.01 | 0.01 | -0.00 | sell |