| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Flagship Pioneering Inc. | 23,117,045 | 23,117,045 | 0 | 2.45 | 1.17 | -1.27 | hold |
| FMR LLC | 19,388,580 | 22,651,419 | +3,262,839 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 6,005,307 | 6,734,821 | +729,514 | 0.00 | 0.00 | -0.00 | buy |
| Hudson Bay Capital Management LP | 4,320,400 | 5,425,000 | +1,104,600 | 0.05 | 0.04 | -0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,094,039 | 2,132,643 | +38,604 | 0.00 | 0.00 | -0.00 | buy |
| Woodline Partners LP | 1,290,276 | 2,045,871 | +755,595 | 0.02 | 0.01 | -0.01 | buy |
| STATE STREET CORP | 1,909,524 | 1,946,363 | +36,839 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 2,362,449 | 1,654,962 | -707,487 | 0.00 | 0.00 | -0.00 | sell |
| Eversept Partners, LP | 1,753,538 | 1,388,944 | -364,594 | 0.24 | 0.08 | -0.16 | sell |
| Handelsbanken Fonder AB | 1,100,000 | 1,100,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| GOLDMAN SACHS GROUP INC | 435,862 | 1,064,137 | +628,275 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,224,075 | 1,027,552 | -1,196,523 | 0.00 | 0.00 | -0.00 | sell |
| TANG CAPITAL MANAGEMENT LLC | 1,792,888 | 907,112 | -885,776 | 0.23 | 0.07 | -0.16 | sell |
| NORTHERN TRUST CORP | 770,611 | 784,693 | +14,082 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 676,387 | 747,318 | +70,931 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,411,050 | 634,603 | -776,447 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 168,518 | 486,353 | +317,835 | 0.00 | 0.00 | +0.00 | buy |
| SIT INVESTMENT ASSOCIATES INC | 342,200 | 342,200 | 0 | 0.01 | 0.01 | -0.01 | hold |
| Lion Point Capital, LP | 340,761 | 340,761 | 0 | 0.43 | 0.50 | +0.08 | hold |
| Bank of New York Mellon Corp | 344,323 | 329,072 | -15,251 | 0.00 | 0.00 | -0.00 | sell |
| Graham Capital Management, L.P. | 161,308 | 309,379 | +148,071 | 0.01 | 0.01 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 363,650 | 298,111 | -65,539 | 0.00 | 0.00 | -0.00 | sell |
| Pennant Investors, LP | 292,300 | 292,300 | 0 | 0.13 | 0.06 | -0.06 | hold |
| AQR CAPITAL MANAGEMENT LLC | 27,662 | 166,887 | +139,225 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0 | 150,000 | +150,000 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 137,519 | 141,453 | +3,934 | 0.00 | 0.00 | -0.00 | buy |
| LPL Financial LLC | 115,530 | 129,775 | +14,245 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 127,660 | 127,660 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Atom Investors LP | 0 | 103,316 | +103,316 | 0.00 | 0.01 | +0.01 | buy |
| Virtu Financial LLC | 0 | 94,510 | +94,510 | 0.00 | 0.01 | +0.01 | buy |
| XTX Topco Ltd | 402,506 | 75,692 | -326,814 | 0.12 | 0.01 | -0.12 | sell |
| Janney Montgomery Scott LLC | 75,098 | 75,098 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 45,311 | 73,871 | +28,560 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 135,178 | 70,756 | -64,422 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 70,598 | +70,598 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 57,000 | 62,966 | +5,966 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 61,977 | 61,977 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 71,259 | 58,776 | -12,483 | 0.00 | 0.00 | -0.00 | sell |
| Kestra Advisory Services, LLC | 21,631 | 51,521 | +29,890 | 0.00 | 0.00 | +0.00 | buy |
| Providence Wealth Advisors, LLC | 675 | 51,000 | +50,325 | 0.42 | 0.03 | -0.39 | buy |
| Mirae Asset Global Investments Co., Ltd. | 0 | 50,102 | +50,102 | 0.00 | 0.00 | +0.00 | buy |
| HARBOURVEST PARTNERS LLC | 49,363 | 49,363 | 0 | 0.02 | 0.02 | -0.01 | hold |
| AMERICAN INTERNATIONAL GROUP, INC. | 48,352 | 48,475 | +123 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 58,045 | 46,549 | -11,496 | 0.00 | 0.00 | -0.00 | sell |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 40,593 | 45,292 | +4,699 | 0.03 | 0.02 | -0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 38,807 | 39,336 | +529 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 40,532 | 33,061 | -7,471 | 0.00 | 0.00 | -0.00 | sell |
| PFG Investments, LLC | 11,500 | 31,443 | +19,943 | 0.00 | 0.00 | -0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 29,158 | 29,008 | -150 | 0.00 | 0.00 | +0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 61,664 | 27,088 | -34,576 | 0.00 | 0.00 | -0.00 | sell |
| Clear Creek Financial Management, LLC | 26,950 | 23,450 | -3,500 | 0.01 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 0 | 22,745 | +22,745 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 38,091 | 21,957 | -16,134 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 0 | 20,874 | +20,874 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 20,000 | 20,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Russell Investments Group, Ltd. | 18,300 | 18,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WOLVERINE TRADING, LLC | 0 | 17,969 | +17,969 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 88,329 | 17,885 | -70,444 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 16,099 | 17,672 | +1,573 | 0.00 | 0.00 | -0.00 | buy |
| Vontobel Holding Ltd. | 17,000 | 17,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Auour Investments LLC | 17,000 | 17,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| VICTORY CAPITAL MANAGEMENT INC | 13,135 | 15,014 | +1,879 | 0.00 | 0.00 | -0.00 | buy |
| HighTower Advisors, LLC | 16,005 | 15,000 | -1,005 | 0.00 | 0.00 | -0.00 | sell |
| MML INVESTORS SERVICES, LLC | 0 | 14,889 | +14,889 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 12,651 | +12,651 | 0.00 | 0.00 | +0.00 | buy |
| Aries Wealth Management | 12,000 | 12,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | 11,368 | +11,368 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 11,233 | +11,233 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 52,080 | 10,376 | -41,704 | 0.00 | 0.00 | -0.00 | sell |
| Diversified Trust Co | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Summit Trail Advisors, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 14,489 | 9,985 | -4,504 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 16,011 | 9,888 | -6,123 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 8,033 | 8,033 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 6,203 | 6,203 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 11,122 | 2,396 | -8,726 | 0.00 | 0.00 | -0.00 | sell |
| TFC Financial Management, Inc. | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Orion Capital Management LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Continuum Advisory, LLC | 0 | 955 | +955 | 0.00 | 0.00 | +0.00 | buy |
| Kelly Financial Services LLC | 240 | 240 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Larson Financial Group LLC | 235 | 235 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HUNTINGTON NATIONAL BANK | 0 | 230 | +230 | 0.00 | 0.00 | +0.00 | buy |
| Sound Income Strategies, LLC | 175 | 175 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CWM, LLC | 0 | 108 | +108 | 0.00 | 0.00 | 0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 108 | +108 | 0.00 | 0.00 | +0.00 | buy |
| Avior Wealth Management, LLC | 0 | 20 | +20 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 817,000 | 0 | -817,000 | 0.00 | 0.00 | -0.00 | sell |
| WEXFORD CAPITAL LP | 20,440 | 0 | -20,440 | 0.01 | 0.00 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 349,588 | 0 | -349,588 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 55,011 | 0 | -55,011 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 393,760 | 0 | -393,760 | 0.00 | 0.00 | -0.00 | sell |
| Quantbot Technologies LP | 24,600 | 0 | -24,600 | 0.00 | 0.00 | -0.00 | sell |
| Parallax Volatility Advisers, L.P. | 43,163 | 0 | -43,163 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 15,304 | 0 | -15,304 | 0.00 | 0.00 | -0.00 | sell |
| MACROVIEW INVESTMENT MANAGEMENT LLC | 5,750 | 0 | -5,750 | 0.01 | 0.00 | -0.01 | sell |
| JANE STREET GROUP, LLC | 290,287 | 0 | -290,287 | 0.00 | 0.00 | -0.00 | sell |
| Arete Wealth Advisors, LLC | 24,700 | 0 | -24,700 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 2,150,000 | 0 | -2,150,000 | 0.01 | 0.00 | -0.01 | sell |
| Squarepoint Ops LLC | 114,000 | 0 | -114,000 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 2,856 | 0 | -2,856 | 0.00 | 0.00 | -0.00 | sell |