| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANE STREET GROUP, LLC | 0 | 10,051,000 | +10,051,000 | 0.00 | 0.01 | +0.01 | buy |
| Paradigm Biocapital Advisors LP | 0 | 351,700 | +351,700 | 0.00 | 2.08 | +2.08 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,264,470 | 1,519,219 | +254,749 | 0.04 | 0.06 | +0.02 | buy |
| Invesco Ltd. | 672,126 | 907,911 | +235,785 | 0.02 | 0.03 | +0.01 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 3,802,177 | 4,030,634 | +228,457 | 2.43 | 2.96 | +0.53 | buy |
| CITADEL ADVISORS LLC | 0 | 171,571 | +171,571 | 0.00 | 0.02 | +0.02 | buy |
| Camber Capital Management LP | 0 | 165,000 | +165,000 | 0.00 | 0.73 | +0.73 | buy |
| JANUS HENDERSON GROUP PLC | 3,854,533 | 3,994,785 | +140,252 | 0.24 | 0.30 | +0.06 | buy |
| Aberdeen Group plc | 0 | 138,791 | +138,791 | 0.00 | 0.04 | +0.04 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 132,176 | +132,176 | 0.00 | 0.37 | +0.37 | buy |
| HSBC HOLDINGS PLC | 0 | 111,107 | +111,107 | 0.00 | 0.01 | +0.01 | buy |
| Tri Locum Partners LP | 0 | 99,550 | +99,550 | 0.00 | 6.15 | +6.15 | buy |
| Schonfeld Strategic Advisors LLC | 38,900 | 124,901 | +86,001 | 0.03 | 0.13 | +0.10 | buy |
| Avoro Capital Advisors LLC | 3,670,000 | 3,755,555 | +85,555 | 5.36 | 6.53 | +1.17 | buy |
| TANG CAPITAL MANAGEMENT LLC | 10,000 | 70,000 | +60,000 | 0.13 | 0.81 | +0.68 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 19,908 | 73,335 | +53,427 | 0.01 | 0.04 | +0.03 | buy |
| BIT Capital GmbH | 9,123 | 61,530 | +52,407 | 0.11 | 0.84 | +0.72 | buy |
| MORGAN STANLEY | 76,682 | 121,876 | +45,194 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 220,553 | 265,157 | +44,604 | 0.03 | 0.05 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 0 | 34,000 | +34,000 | 0.00 | 0.03 | +0.03 | buy |
| Pictet Asset Management Holding SA | 170,870 | 203,654 | +32,784 | 0.02 | 0.03 | +0.01 | buy |
| Jefferies Financial Group Inc. | 2,500 | 28,000 | +25,500 | 0.01 | 0.06 | +0.05 | buy |
| Altium Capital Management LLC | 0 | 25,000 | +25,000 | 0.00 | 2.17 | +2.17 | buy |
| Saturn V Capital Management LP | 112,473 | 131,759 | +19,286 | 4.41 | 6.35 | +1.94 | buy |
| Cubist Systematic Strategies, LLC | 0 | 18,891 | +18,891 | 0.00 | 0.03 | +0.03 | buy |
| Woodline Partners LP | 0 | 16,149 | +16,149 | 0.00 | 0.02 | +0.02 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 16,046 | +16,046 | 0.00 | 0.01 | +0.01 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 14,102 | +14,102 | 0.00 | 0.17 | +0.17 | buy |
| Jump Financial, LLC | 0 | 13,346 | +13,346 | 0.00 | 0.05 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 409,973 | 422,854 | +12,881 | 0.01 | 0.01 | +0.00 | buy |
| Capital International Investors | 2,168,443 | 2,181,268 | +12,825 | 0.05 | 0.06 | +0.01 | buy |
| HAP Trading, LLC | 0 | 12,299 | +12,299 | 0.00 | 0.45 | +0.45 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 7,415 | 19,580 | +12,165 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 361,029 | 372,414 | +11,385 | 0.02 | 0.02 | +0.00 | buy |
| Trexquant Investment LP | 0 | 9,868 | +9,868 | 0.00 | 0.03 | +0.03 | buy |
| Matisse Capital | 26,255 | 34,635 | +8,380 | 1.74 | 2.32 | +0.59 | buy |
| JANE STREET GROUP, LLC | 24,717 | 31,468 | +6,751 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 6,300 | +6,300 | 0.00 | 0.21 | +0.21 | buy |
| FIL Ltd | 0 | 5,998 | +5,998 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 5,881 | +5,881 | 0.00 | 0.00 | +0.00 | buy |
| Sequoia Financial Advisors, LLC | 0 | 5,811 | +5,811 | 0.00 | 0.01 | +0.01 | buy |
| CIBC Private Wealth Group LLC | 0 | 5,668 | +5,668 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 328 | 5,719 | +5,391 | 0.00 | 0.01 | +0.01 | buy |
| T. Rowe Price Investment Management, Inc. | 3,984,503 | 3,989,830 | +5,327 | 0.26 | 0.33 | +0.06 | buy |
| Quantbot Technologies LP | 0 | 5,300 | +5,300 | 0.00 | 0.04 | +0.04 | buy |
| China Universal Asset Management Co., Ltd. | 1,462 | 6,635 | +5,173 | 0.04 | 0.16 | +0.12 | buy |
| GTS SECURITIES LLC | 0 | 4,316 | +4,316 | 0.00 | 0.01 | +0.01 | buy |
| CAPTRUST FINANCIAL ADVISORS | 24,029 | 28,051 | +4,022 | 0.01 | 0.01 | +0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 3,997 | +3,997 | 0.00 | 0.05 | +0.05 | buy |
| NEOS Investment Management LLC | 0 | 3,782 | +3,782 | 0.00 | 0.05 | +0.05 | buy |
| Allianz Asset Management GmbH | 0 | 3,600 | +3,600 | 0.00 | 0.00 | +0.00 | buy |
| Penserra Capital Management LLC | 0 | 3,448 | +3,448 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 3,032 | +3,032 | 0.00 | 0.02 | +0.02 | buy |
| Maven Securities LTD | 0 | 3,000 | +3,000 | 0.00 | 0.04 | +0.04 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 2,986 | +2,986 | 0.00 | 0.10 | +0.10 | buy |
| GROUP ONE TRADING LLC | 2,844 | 5,808 | +2,964 | 0.01 | 0.02 | +0.01 | buy |
| Bayesian Capital Management, LP | 3,129 | 5,561 | +2,432 | 0.03 | 0.07 | +0.04 | buy |
| WEDBUSH SECURITIES INC | 0 | 2,413 | +2,413 | 0.00 | 0.01 | +0.01 | buy |
| SIMPLEX TRADING, LLC | 0 | 2,270 | +2,270 | 0.00 | 0.01 | +0.01 | buy |
| CERTUITY, LLC | 0 | 2,144 | +2,144 | 0.00 | 0.03 | +0.03 | buy |
| AMERIPRISE FINANCIAL INC | 60,576 | 62,310 | +1,734 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 1,162 | +1,162 | 0.00 | 0.00 | +0.00 | buy |
| BAROMETER CAPITAL MANAGEMENT INC. | 0 | 1,000 | +1,000 | 0.00 | 0.04 | +0.04 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 745 | 1,744 | +999 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 2,540 | 3,231 | +691 | 0.01 | 0.02 | +0.00 | buy |
| Avior Wealth Management, LLC | 7,177 | 7,822 | +645 | 0.05 | 0.06 | +0.01 | buy |
| ROYAL BANK OF CANADA | 6,863 | 7,435 | +572 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 54,555 | 55,090 | +535 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 9,935 | 10,465 | +530 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 30,727 | 31,252 | +525 | 0.00 | 0.00 | +0.00 | buy |
| Gilbert & Cook, Inc. | 2,618 | 2,838 | +220 | 0.04 | 0.05 | +0.01 | buy |
| SECTORAL ASSET MANAGEMENT INC | 4,241 | 4,441 | +200 | 0.08 | 0.24 | +0.16 | buy |
| Mirae Asset Global Investments Co., Ltd. | 13,803 | 13,989 | +186 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 16,151 | 16,313 | +162 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 167 | 318 | +151 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 145 | +145 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 121 | +121 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 38 | 156 | +118 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 242 | 333 | +91 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 210 | 284 | +74 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 845 | 915 | +70 | 0.00 | 0.01 | +0.00 | buy |
| Evolutionary Tree Capital Management, LLC | 16,657 | 16,726 | +69 | 2.01 | 2.33 | +0.31 | buy |
| Coppell Advisory Solutions LLC | 76 | 141 | +65 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 1,268 | 1,290 | +22 | 0.00 | 0.00 | +0.00 | buy |
| PRIVATE TRUST CO NA | 33 | 44 | +11 | 0.00 | 0.00 | +0.00 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 3,672 | 3,681 | +9 | 0.01 | 0.01 | -0.00 | buy |
| Bell Investment Advisors, Inc | 42 | 43 | +1 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 0 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ZAZOVE ASSOCIATES LLC | 0 | 0 | 0 | 1.78 | 2.33 | +0.55 | hold |
| D. E. Shaw & Co., Inc. | 0 | 0 | 0 | 0.04 | 0.03 | -0.00 | hold |
| BESSEMER GROUP INC | 544 | 544 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NOMURA ASSET MANAGEMENT CO LTD | 12,668 | 12,668 | 0 | 0.01 | 0.01 | +0.00 | hold |
| CSS LLC/IL | 0 | 0 | 0 | 0.00 | 1.01 | +1.01 | hold |
| AVIVA PLC | 0 | 0 | 0 | 0.11 | 0.10 | -0.01 | hold |
| LINDEN ADVISORS LP | 0 | 0 | 0 | 0.08 | 0.24 | +0.16 | hold |
| WOLVERINE ASSET MANAGEMENT LLC | 0 | 0 | 0 | 2.37 | 2.26 | -0.12 | hold |
| Context Capital Management, LLC | 0 | 0 | 0 | 0.96 | 1.18 | +0.21 | hold |
| Calamos Advisors LLC | 0 | 0 | 0 | 0.04 | 0.04 | +0.00 | hold |
| Nicholas Investment Partners, LP | 0 | 0 | 0 | 0.20 | 0.36 | +0.15 | hold |
| DAFNA Capital Management LLC | 0 | 0 | 0 | 1.15 | 0.99 | -0.16 | hold |