| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Two Seas Capital LP | 20,529,685 | 22,580,701 | +2,051,016 | 0.63 | 0.53 | -0.10 | buy |
| Empirical Finance, LLC | 0 | 800,000 | +800,000 | 0.00 | 0.01 | +0.01 | buy |
| Almitas Capital LLC | 0 | 109,054 | +109,054 | 0.00 | 0.01 | +0.01 | buy |
| XTX Topco Ltd | 0 | 80,022 | +80,022 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,813,860 | 1,882,860 | +69,000 | 0.00 | 0.00 | +0.00 | buy |
| Key Client Fiduciary Advisors, LLC | 150,150 | 175,555 | +25,405 | 0.01 | 0.02 | +0.00 | buy |
| &PARTNERS | 0 | 20,000 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| PKS Advisory Services, LLC | 0 | 17,000 | +17,000 | 0.00 | 0.00 | +0.00 | buy |
| Baader Bank Aktiengesellschaft | 0 | 14,935 | +14,935 | 0.00 | 0.00 | +0.00 | buy |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 421,292 | 426,714 | +5,422 | 0.00 | 0.00 | +0.00 | buy |
| IFG Advisory, LLC | 10,000 | 11,725 | +1,725 | 0.00 | 0.00 | +0.00 | buy |
| Garde Capital, Inc. | 0 | 750 | +750 | 0.00 | 0.00 | +0.00 | buy |
| COLUMBIA ADVISORY PARTNERS LLC | 36,530 | 36,730 | +200 | 0.01 | 0.01 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 153 | +153 | 0.00 | 0.00 | +0.00 | buy |
| Koesten, Hirschmann & Crabtree, INC. | 0 | 47 | +47 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 213 | 213 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rathbones Group PLC | 432,818 | 432,818 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Plante Moran Financial Advisors, LLC | 925 | 925 | 0 | 0.00 | 0.00 | -0.00 | hold |
| State of New Jersey Common Pension Fund D | 54,718 | 54,718 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEA Management Company, LLC | 17,079,778 | 17,079,778 | 0 | 0.26 | 0.31 | +0.05 | hold |
| Newman Dignan & Sheerar, Inc. | 27,957 | 27,957 | 0 | 0.00 | 0.00 | +0.00 | hold |
| EcoR1 Capital, LLC | 27,404,070 | 27,404,070 | 0 | 0.32 | 0.39 | +0.07 | hold |
| State of Tennessee, Department of Treasury | 73,376 | 73,376 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rock Springs Capital Management LP | 2,483,468 | 2,483,468 | 0 | 0.03 | 0.04 | +0.01 | hold |
| Long Focus Capital Management, LLC | 23,756,687 | 23,756,687 | 0 | 0.32 | 0.37 | +0.05 | hold |
| Ausdal Financial Partners, Inc. | 12,476 | 12,476 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Parallel Advisors, LLC | 250 | 250 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIMON QUICK ADVISORS, LLC | 30,000 | 30,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| X-Square Capital, LLC | 11,173 | 11,173 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Investors Research Corp | 100 | 100 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HighMark Wealth Management LLC | 287 | 287 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SBI Securities Co., Ltd. | 10 | 10 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD Waterhouse Canada Inc. | 14 | 14 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 53,186 | 53,186 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Transce3nd, LLC | 175 | 175 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Raiffeisen Bank International AG | 907 | 907 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SEI INVESTMENTS CO | 54,824 | 54,824 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHERN TRUST CORP | 51,333 | 51,333 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Wilmington Savings Fund Society, FSB | 604 | 604 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Farther Finance Advisors, LLC | 20 | 0 | -20 | 0.00 | 0.00 | -0.00 | sell |
| Prosperity Wealth Management, Inc. | 19,798 | 19,763 | -35 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 147 | 0 | -147 | 0.00 | 0.00 | -0.00 | sell |
| CAPTRUST FINANCIAL ADVISORS | 80,609 | 79,083 | -1,526 | 0.00 | 0.00 | +0.00 | sell |
| Banque Transatlantique SA | 1,824 | 0 | -1,824 | 0.00 | 0.00 | -0.00 | sell |
| CIBC Private Wealth Group LLC | 3,023 | 0 | -3,023 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 26,469 | 23,007 | -3,462 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 183,686 | 179,087 | -4,599 | 0.00 | 0.00 | +0.00 | sell |
| Global Retirement Partners, LLC | 6,000 | 0 | -6,000 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 18,313 | 8,533 | -9,780 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 10,113 | 0 | -10,113 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 21,966 | 10,921 | -11,045 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 26,816 | 10,816 | -16,000 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 16,149 | 0 | -16,149 | 0.00 | 0.00 | -0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 25,261 | 0 | -25,261 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 26,064 | 0 | -26,064 | 0.00 | 0.00 | -0.00 | sell |
| CSS LLC/IL | 30,702 | 0 | -30,702 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 109,066 | 67,032 | -42,034 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 50,068 | 2,534 | -47,534 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 78,031 | 0 | -78,031 | 0.00 | 0.00 | -0.00 | sell |
| Graham Capital Management, L.P. | 87,274 | 0 | -87,274 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 94,283 | 0 | -94,283 | 0.00 | 0.00 | -0.00 | sell |
| Clear Harbor Asset Management, LLC | 240,725 | 145,400 | -95,325 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 135,947 | 0 | -135,947 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 206,732 | 13,304 | -193,428 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 2,218,215 | 1,964,141 | -254,074 | 0.00 | 0.00 | -0.00 | sell |
| MPM BioImpact LLC | 4,894,344 | 4,411,821 | -482,523 | 0.17 | 0.18 | +0.02 | sell |
| MPM ASSET MANAGEMENT LLC | 5,335,715 | 4,809,677 | -526,038 | 1.51 | 2.66 | +1.15 | sell |
| JPMORGAN CHASE & CO | 882,331 | 0 | -882,331 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 1,754,889 | 464,278 | -1,290,611 | 0.00 | 0.00 | -0.00 | sell |