| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 0 | 3,213,500 | +3,213,500 | 0.00 | 0.05 | +0.05 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,787,730 | 5,987,730 | +2,200,000 | 0.05 | 0.06 | +0.01 | buy |
| CITADEL ADVISORS LLC | 0 | 1,982,252 | +1,982,252 | 0.00 | 0.01 | +0.01 | buy |
| MAVERICK CAPITAL LTD | 6,594,319 | 8,447,804 | +1,853,485 | 0.89 | 0.88 | -0.01 | buy |
| Maven Securities LTD | 0 | 1,452,778 | +1,452,778 | 0.00 | 0.84 | +0.84 | buy |
| Artal Group S.A. | 2,000,000 | 3,007,400 | +1,007,400 | 0.50 | 0.52 | +0.02 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 17,202,009 | 18,202,009 | +1,000,000 | 1.95 | 1.44 | -0.51 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 587,575 | +587,575 | 0.00 | 0.04 | +0.04 | buy |
| FMR LLC | 660,425 | 1,202,215 | +541,790 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,269,162 | 1,627,363 | +358,201 | 0.00 | 0.00 | +0.00 | buy |
| M28 Capital Management LP | 7,044,500 | 7,373,413 | +328,913 | 46.45 | 30.85 | -15.60 | buy |
| MARSHALL WACE, LLP | 181,638 | 500,209 | +318,571 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 148,960 | 432,933 | +283,973 | 0.01 | 0.03 | +0.02 | buy |
| MILLENNIUM MANAGEMENT LLC | 254,894 | 514,581 | +259,687 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 212,377 | +212,377 | 0.00 | 0.01 | +0.01 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 455,331 | 655,331 | +200,000 | 0.10 | 0.13 | +0.03 | buy |
| Laurion Capital Management LP | 871,500 | 1,071,500 | +200,000 | 0.13 | 0.19 | +0.06 | buy |
| MORGAN STANLEY | 0 | 190,328 | +190,328 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 17,527 | 181,267 | +163,740 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 1,228,683 | 1,391,561 | +162,878 | 0.08 | 0.08 | -0.01 | buy |
| Swiss National Bank | 0 | 152,400 | +152,400 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,182,602 | 1,312,425 | +129,823 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 514,910 | 626,450 | +111,540 | 0.00 | 0.00 | -0.00 | buy |
| Monashee Investment Management LLC | 0 | 103,300 | +103,300 | 0.00 | 0.09 | +0.09 | buy |
| JANE STREET GROUP, LLC | 0 | 79,438 | +79,438 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 75,800 | +75,800 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 1,194,747 | 1,263,729 | +68,982 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 13,047 | 78,661 | +65,614 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,395,137 | 1,459,764 | +64,627 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 57,026 | +57,026 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 24,883 | 81,584 | +56,701 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 36,352 | 88,970 | +52,618 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 82,319 | 133,406 | +51,087 | 0.00 | 0.00 | +0.00 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 50,000 | +50,000 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 341,794 | 391,132 | +49,338 | 0.00 | 0.00 | -0.00 | buy |
| KRAEMATON INVESTMENT ADVISORS, INC | 0 | 47,000 | +47,000 | 0.00 | 0.26 | +0.26 | buy |
| Legal & General Group Plc | 4,738 | 49,356 | +44,618 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 162,692 | 205,746 | +43,054 | 0.00 | 0.00 | -0.00 | buy |
| Birchview Capital, LP | 0 | 40,000 | +40,000 | 0.00 | 0.16 | +0.16 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 36,580 | +36,580 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 34,432 | +34,432 | 0.00 | 0.01 | +0.01 | buy |
| Trexquant Investment LP | 0 | 32,119 | +32,119 | 0.00 | 0.00 | +0.00 | buy |
| James J. Burns & Company, LLC | 33,049 | 65,049 | +32,000 | 0.05 | 0.08 | +0.03 | buy |
| MetLife Investment Management, LLC | 0 | 31,423 | +31,423 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 10,376 | 41,234 | +30,858 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,000 | 32,250 | +30,250 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 26,820 | +26,820 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 26,543 | +26,543 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 25,999 | +25,999 | 0.00 | 0.00 | +0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 43,617 | 68,807 | +25,190 | 0.01 | 0.01 | +0.00 | buy |
| Cinctive Capital Management LP | 0 | 25,000 | +25,000 | 0.00 | 0.01 | +0.01 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 20,053 | +20,053 | 0.00 | 0.03 | +0.03 | buy |
| Arizona State Retirement System | 0 | 17,943 | +17,943 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 0 | 17,292 | +17,292 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 44,979 | 62,226 | +17,247 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 0 | 17,105 | +17,105 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 14,681 | +14,681 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 12,600 | +12,600 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 11,900 | +11,900 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,019 | 11,335 | +9,316 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 264,885 | 274,093 | +9,208 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 1,259 | 10,353 | +9,094 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 2,536 | 11,456 | +8,920 | 0.00 | 0.01 | +0.01 | buy |
| SG Americas Securities, LLC | 25,868 | 34,562 | +8,694 | 0.00 | 0.00 | -0.00 | buy |
| State of Wyoming | 0 | 7,244 | +7,244 | 0.00 | 0.01 | +0.01 | buy |
| Invesco Ltd. | 32,072 | 37,777 | +5,705 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 14,660 | 18,259 | +3,599 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 111,511 | 114,595 | +3,084 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 177,524 | 180,418 | +2,894 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 460,563 | 462,717 | +2,154 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 14,152 | 16,116 | +1,964 | 0.00 | 0.00 | -0.00 | buy |
| US BANCORP \DE\ | 0 | 732 | +732 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 24,157 | 24,792 | +635 | 0.00 | 0.00 | -0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 6,373 | 6,671 | +298 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 250 | +250 | 0.00 | 0.00 | +0.00 | buy |
| Chicago Partners Investment Group LLC | 11,136 | 11,303 | +167 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 11,073 | 11,168 | +95 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 80 | +80 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 48 | +48 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 4,883 | 4,883 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MACQUARIE GROUP LTD | 81,955 | 81,955 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Daiwa Securities Group Inc. | 349 | 349 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NJ State Employees Deferred Compensation Plan | 11,700 | 11,700 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Newtyn Management, LLC | 510,000 | 510,000 | 0 | 0.72 | 0.51 | -0.22 | hold |
| Matisse Capital | 12,013 | 12,013 | 0 | 0.05 | 0.03 | -0.02 | hold |
| Bellevue Group AG | 4,494,458 | 4,494,458 | 0 | 0.42 | 0.35 | -0.07 | hold |
| Parallel Advisors, LLC | 95 | 95 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 1,200 | 1,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Kynam Capital Management, LP | 3,932,082 | 3,932,082 | 0 | 3.76 | 2.25 | -1.51 | hold |
| SEI INVESTMENTS CO | 29,000 | 29,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| METROPOLITAN LIFE INSURANCE CO/NY | 3,256 | 3,256 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WS MANAGEMENT LLLP | 192,722 | 192,722 | 0 | 0.14 | 0.10 | -0.05 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 169,693 | 169,693 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 16,950 | 16,950 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMERICAN INTERNATIONAL GROUP, INC. | 29,509 | 29,390 | -119 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 7,923 | 7,803 | -120 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 314 | 173 | -141 | 0.00 | 0.00 | -0.00 | sell |
| TD Waterhouse Canada Inc. | 400 | 0 | -400 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 5,751 | 5,158 | -593 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 28,171 | 27,457 | -714 | 0.00 | 0.00 | -0.00 | sell |